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References (148)
-
Michael Lam, Qinghua Liu, S. Elledge, J. Rosen (2004)
Chk1 is haploinsufficient for multiple functions critical to tumor suppression.Cancer cell, 6 1
-
C McMurray (2010)
10.1038/nrg2828Nat. Rev. Genet., 11
-
H. Mankouri, D. Huttner, I. Hickson (2013)
How unfinished business from S‐phase affects mitosis and beyondThe EMBO Journal, 32
-
B. Shiotani, Hai Nguyen, Pelle Håkansson, Alexandre Maréchal, A. Tse, H. Tahara, L. Zou (2013)
Two distinct modes of ATR activation orchestrated by Rad17 and Nbs1.Cell reports, 3 5
-
Jessica Williams, Dana Smith, Lisette Marjavaara, S. Lujan, A. Chabes, T. Kunkel (2013)
Topoisomerase 1-mediated removal of ribonucleotides from nascent leading-strand DNA.Molecular cell, 49 5
-
T. Stracker, J. Petrini (2011)
The MRE11 complex: starting from the endsNature Reviews Molecular Cell Biology, 12
-
Alberto Ciccia, Andrea Bredemeyer, M. Sowa, M. Terret, P. Jallepalli, J. Harper, S. Elledge (2009)
The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restart.Genes & development, 23 20
-
Benoît Tallec, G. Millot, M. Blin, O. Brison, B. Dutrillaux, M. Debatisse (2013)
Common fragile site profiling in epithelial and erythroid cells reveals that most recurrent cancer deletions lie in fragile sites hosting large genes.Cell reports, 4 3
-
Lingchuan Hu, Tae Kim, M. Son, Sung-A Kim, Cory Holland, S. Tateishi, D. Kim, P. Yew, C. Montagna, Lavinia Dumitrache, P. Hasty (2013)
Two Replication Fork Maintenance Pathways Fuse Inverted Repeats to Rearrange ChromosomesNature, 501
-
Frank Couch, Carol Bansbach, R. Driscoll, Jessica Luzwick, Gloria Glick, R. Bétous, Clinton Carroll, S. Jung, J. Qin, Karlene Cimprich, D. Cortez (2013)
ATR phosphorylates SMARCAL1 to prevent replication fork collapse.Genes & development, 27 14
-
Federico Lazzaro, Daniele Novarina, Flavio Amara, Danielle Watt, Jana Stone, V. Costanzo, P. Burgers, T. Kunkel, P. Plevani, M. Muzi-Falconi (2012)
RNase H and Postreplication Repair Protect Cells from Ribonucleotides Incorporated in DNAMolecular Cell, 45
-
A. Carr, S. Lambert (2013)
Replication stress-induced genome instability: the dark side of replication maintenance by homologous recombination.Journal of molecular biology, 425 23
-
Manzar Hossain, B. Stillman (2012)
Meier-Gorlin syndrome mutations disrupt an Orc1 CDK inhibitory domain and cause centrosome reduplication.Genes & development, 26 16
-
C. MacDougall, T. Byun, Christopher Van, M. Yee, Karlene Cimprich (2007)
The structural determinants of checkpoint activation.Genes & development, 21 8
-
Dongqing Huang, B. Piening, A. Paulovich (2013)
The Preference for Error-Free or Error-Prone Postreplication Repair in Saccharomyces cerevisiae Exposed to Low-Dose Methyl Methanesulfonate Is Cell Cycle DependentMolecular and Cellular Biology, 33
-
J. Barlow, R. Faryabi, E. Callen, N. Wong, Amy Malhowski, H. Chen, G. Gutierrez-Cruz, Hong-Wei Sun, P. Mckinnon, George Wright, R. Casellas, D. Robbiani, L. Staudt, O. Fernandez-Capetillo, A. Nussenzweig (2013)
Identification of Early Replicating Fragile Sites that Contribute to Genome InstabilityCell, 152
-
O. Gilad, B. Nabet, Ryan Ragland, David Schoppy, Kevin Smith, A. Durham, E. Brown (2010)
Combining ATR suppression with oncogenic Ras synergistically increases genomic instability, causing synthetic lethality or tumorigenesis in a dosage-dependent manner.Cancer research, 70 23
-
E. Nam, D. Cortez (2011)
ATR signalling: more than meeting at the fork.The Biochemical journal, 436 3
-
P. Stankiewicz, J. Lupski (2010)
Structural variation in the human genome and its role in disease.Annual review of medicine, 61
-
Pauline Chabosseau, Géraldine Buhagiar-Labarchède, Rosine Onclercq-Delic, S. Lambert, M. Debatisse, O. Brison, M. Amor-Guéret (2011)
Pyrimidine pool imbalance induced by BLM helicase deficiency contributes to genetic instability in Bloom syndrome.Nature communications, 2
-
Emmanouil Fokas, Emmanouil Fokas, R. Prevo, E. Hammond, Thomas Brunner, Thomas Brunner, W. Mckenna, R. Muschel (2014)
Targeting ATR in DNA damage response and cancer therapeutics.Cancer treatment reviews, 40 1
-
A. Baradaran-Heravi, K. Cho, B. Tolhuis, M. Sanyal, O. Morozova, M. Morimoto, L. Elizondo, D. Bridgewater, J. Lubieniecka, Kimberly Beirnes, C. Myung, D. Leung, Hok Fam, K. Choi, Y. Huang, K. Dionis, J. Zonana, Kory Keller, P. Stenzel, C. Mayfield, T. Lücke, A. Bokenkamp, M. Marra, M. Lohuizen, D. Lewis, C. Shaw, C. Boerkoel (2012)
Penetrance of biallelic SMARCAL1 mutations is associated with environmental and genetic disturbances of gene expression.Human molecular genetics, 21 11
-
F Hildebrandt, T Benzing, N Katsanis (2011)
CiliopathiesN. Engl. J. Med., 364
-
David Schoppy, Ryan Ragland, O. Gilad, Nishita Shastri, Ashley Peters, M. Murga, O. Fernandez-Capetillo, J. Diehl, Eric Brown (2012)
Oncogenic stress sensitizes murine cancers to hypomorphic suppression of ATR.The Journal of clinical investigation, 122 1
-
(2010)
where, when, and how? Annu -
V. Naim, Therese Wilhelm, M. Debatisse, F. Rosselli (2013)
ERCC1 and MUS81–EME1 promote sister chromatid separation by processing late replication intermediates at common fragile sites during mitosisNature Cell Biology, 15
-
I. Rosado, Frédéric Langevin, Gerry Crossan, M. Takata, K. Patel (2011)
Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathwayNature Structural &Molecular Biology, 18
-
C. Sørensen, R. Syljuåsen (2011)
Safeguarding genome integrity: the checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replicationNucleic Acids Research, 40
-
Nayun Kim, Shar-yin Huang, Jessica Williams, Yue Li, A. Clark, Jang-Eun Cho, T. Kunkel, Y. Pommier, S. Jinks-Robertson (2011)
Mutagenic Processing of Ribonucleotides in DNA by Yeast Topoisomerase IScience, 332
-
F Hildebrandt (2011)
10.1056/NEJMra1010172N. Engl. J. Med., 364
-
T. Hishida, Yoshino Kubota, A. Carr, H. Iwasaki (2009)
RAD6–RAD18–RAD5-pathway-dependent tolerance to chronic low-dose ultraviolet lightNature, 457
-
Weibin Zhou, E. Otto, A. Cluckey, R. Airik, T. Hurd, M. Chaki, Katrina Diaz, Francis Lach, Geoffrey Bennett, H. Gee, A. Ghosh, S. Natarajan, Supawat Thongthip, Uma Veturi, Susan Allen, Sabine Janssen, Gokul Ramaswami, J. Dixon, F. Burkhalter, M. Spoendlin, H. Moch, M. Mihatsch, J. Vérine, R. Reade, H. Soliman, M. Godin, D. Kiss, G. Monga, G. Mazzucco, K. Amann, F. Artunc, R. Newland, T. Wiech, S. Zschiedrich, T. Huber, A. Friedl, G. Slaats, J. Joles, R. Goldschmeding, J. Washburn, R. Giles, S. Levy, A. Smogorzewska, F. Hildebrandt (2012)
FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repairNature genetics, 44
-
M. O’Driscoll, P. Jeggo (2008)
The role of the DNA damage response pathways in brain development and microcephaly: insight from human disorders.DNA repair, 7 7
-
X. Ge, D. Jackson, J. Blow (2007)
Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress.Genes & development, 21 24
-
Hyo Choi, Jia-Ren Lin, Jean-Baptiste Vannier, G. Slaats, Andrew Kile, R. Paulsen, Danielle Manning, D. Beier, R. Giles, S. Boulton, Karlene Cimprich (2013)
NEK8 links the ATR-regulated replication stress response and S phase CDK activity to renal ciliopathies.Molecular cell, 51 4
-
K. Ask, Zuzana Jasencakova, Patrice Ménard, Yunpeng Feng, G. Almouzni, Anja Groth (2012)
Codanin‐1, mutated in the anaemic disease CDAI, regulates Asf1 function in S‐phase histone supplyThe EMBO Journal, 31
-
Joon Lee, W. Dunphy (2013)
The Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forksMolecular Biology of the Cell, 24
-
R. Burrell, S. McClelland, D. Endesfelder, Petra Groth, Marie-Christine Weller, Nadeem Shaikh, E. Domingo, N. Kanu, S. Dewhurst, E. Gronroos, S. Chew, A. Rowan, Arne Schenk, Michal Sheffer, M. Howell, Maik Kschischo, A. Behrens, T. Helleday, J. Bartek, I. Tomlinson, C. Swanton (2013)
Replication stress links structural and numerical cancer chromosomal instabilityNature, 494
-
K Ask (2012)
10.1038/emboj.2012.55EMBO J., 31
-
J. Saldivar, S. Miuma, J. Bene, S. Hosseini, Hidetaka Shibata, Jin Sun, L. Wheeler, C. Mathews, K. Huebner (2012)
Initiation of Genome Instability and Preneoplastic Processes through Loss of Fhit ExpressionPLoS Genetics, 8
-
Anna Woodward, T. Göhler, M. Luciani, M. Oehlmann, X. Ge, A. Gartner, D. Jackson, J. Blow (2006)
Excess Mcm2–7 license dormant origins of replication that can be used under conditions of replicative stressThe Journal of Cell Biology, 173
-
A. López-Contreras, P. Gutierrez-Martinez, Julia Specks, Sara Rodrigo-Perez, O. Fernandez-Capetillo (2012)
An extra allele of Chk1 limits oncogene-induced replicative stress and promotes transformationThe Journal of Experimental Medicine, 209
-
Amaya Alzu, Rodrigo Bermejo, M. Begnis, C. Lucca, D. Piccini, Walter Carotenuto, Marco Saponaro, Alessandra Brambati, A. Cocito, M. Foiani, G. Liberi (2012)
Senataxin Associates with Replication Forks to Protect Fork Integrity across RNA-Polymerase-II-Transcribed GenesCell, 151
-
Justin Sparks, H. Chon, S. Cerritelli, T. Kunkel, E. Johansson, R. Crouch, P. Burgers (2012)
RNase H2-initiated ribonucleotide excision repair.Molecular cell, 47 6
-
K. Hanada, K. Hanada, Magda Budzowska, S. Davies, E. Drunen, Hideo Onizawa, H. Beverloo, A. Maas, J. Essers, I. Hickson, R. Kanaar (2007)
The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaksNature Structural &Molecular Biology, 14
-
S Tuduri (2009)
10.1038/ncb1984Nat. Cell Biol., 11
-
R. Bétous, Frank Couch, A. Mason, B. Eichman, M. Manosas, D. Cortez (2013)
Substrate-selective repair and restart of replication forks by DNA translocases.Cell reports, 3 6
-
K. Labib, Giacomo Piccoli (2011)
Surviving chromosome replication: the many roles of the S-phase checkpoint pathwayPhilosophical Transactions of the Royal Society B: Biological Sciences, 366
-
T. Ogi, Sarah Walker, T. Stiff, E. Hobson, S. Limsirichaikul, G. Carpenter, K. Prescott, M. Suri, Philip Byrd, M. Matsuse, N. Mitsutake, Y. Nakazawa, P. Vasudevan, M. Barrow, Grant Stewart, A. Taylor, M. O’Driscoll, P. Jeggo (2012)
Identification of the First ATRIP–Deficient Patient and Novel Mutations in ATR Define a Clinical Spectrum for ATR–ATRIP Seckel SyndromePLoS Genetics, 8
-
Yanwen Jiang, I. Lucas, David Young, E. Davis, T. Karrison, J. Rest, M. Beau (2009)
Common fragile sites are characterized by histone hypoacetylationHuman Molecular Genetics, 18
-
A. Aguilera, Tatiana García-Muse (2013)
Causes of genome instability.Annual review of genetics, 47
-
S. Lambert, A. Carr (2013)
Impediments to replication fork movement: stabilisation, reactivation and genome instabilityChromosoma, 122
-
N. Shima, A. Alcaraz, Ivan Liachko, Tavanna Buske, C. Andrews, R. Munroe, S. Hartford, B. Tye, J. Schimenti (2007)
A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in miceNature Genetics, 39
-
J. Bianco, Jérôme Poli, Julie Saksouk, J. Bacal, M. Silva, Kazumasa Yoshida, Yea-Lih Lin, H. Tourrière, Armelle Lengronne, P. Pasero (2012)
Analysis of DNA replication profiles in budding yeast and mammalian cells using DNA combing.Methods, 57 2
-
H. Masai, S. Matsumoto, Z. You, N. Yoshizawa-Sugata, M. Oda (2010)
Eukaryotic chromosome DNA replication: where, when, and how?Annual review of biochemistry, 79
-
J Broers (2004)
10.1002/path.1655J. Pathol., 204
-
Frédéric Langevin, Gerry Crossan, I. Rosado, M. Arends, K. Patel (2011)
Fancd2 counteracts the toxic effects of naturally produced aldehydes in miceNature, 475
-
J. Sogo, M. Lopes, M. Foiani (2002)
Fork Reversal and ssDNA Accumulation at Stalled Replication Forks Owing to Checkpoint DefectsScience, 297
-
Cecilia Cotta-Ramusino, D. Fachinetti, C. Lucca, Ylli Doksani, M. Lopes, J. Sogo, M. Foiani (2005)
Exo1 processes stalled replication forks and counteracts fork reversal in checkpoint-defective cells.Molecular cell, 17 1
-
M. Debatisse, Benoît Tallec, A. Letessier, B. Dutrillaux, O. Brison (2012)
Common fragile sites: mechanisms of instability revisited.Trends in genetics : TIG, 28 1
-
T. Byun, Marcin Pacek, M. Yee, J. Walter, Karlene Cimprich (2005)
Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.Genes & development, 19 9
-
M. Lavin, A. Yeo, O. Becherel (2013)
Senataxin protects the genome Implications for neurodegeneration and other abnormalities -
K. Schlacher, Hong Wu, M. Jasin (2012)
A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2.Cancer cell, 22 1
-
Niels Mailand, Ian Gibbs-Seymour, Simon Bekker-Jensen (2013)
Regulation of PCNA–protein interactions for genome stabilityNature Reviews Molecular Cell Biology, 14
-
Carol Bansbach, R. Bétous, Courtney Lovejoy, Gloria Glick, D. Cortez (2009)
The annealing helicase SMARCAL1 maintains genome integrity at stalled replication forks.Genes & development, 23 20
-
Rodrigo Bermejo, T. Capra, V. González-Huici, D. Fachinetti, A. Cocito, G. Natoli, Y. Katou, Hiroshi Mori, K. Kurokawa, K. Shirahige, M. Foiani (2009)
Genome-Organizing Factors Top2 and Hmo1 Prevent Chromosome Fragility at Sites of S phase TranscriptionCell, 138
-
Tsuyoshi Kawabata, Spencer Luebben, S. Yamaguchi, I. Ilves, I. Matīse, Tavanna Buske, M. Botchan, N. Shima (2011)
Stalled fork rescue via dormant replication origins in unchallenged S phase promotes proper chromosome segregation and tumor suppression.Molecular cell, 41 5
-
J. Tercero, J. Diffley (2001)
Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpointNature, 412
-
Matthew Bochman, K. Paeschke, V. Zakian (2012)
DNA secondary structures: stability and function of G-quadruplex structuresNature Reviews Genetics, 13
-
Kara Bernstein, S. Gangloff, R. Rothstein (2010)
The RecQ DNA helicases in DNA repair.Annual review of genetics, 44
-
K. Paeschke, K. Paeschke, Matthew Bochman, P. Garcia, P. Cejka, P. Cejka, K. Friedman, S. Kowalczykowski, V. Zakian (2013)
Pif1 family helicases suppress genome instability at G-quadruplex motifsNature, 497
-
M. Murga, S. Bunting, M. Montaña, Rebeca Soria, F. Mulero, M. Cañamero, Youngsoo Lee, P. Mckinnon, A. Nussenzweig, O. Fernandez-Capetillo (2009)
A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated agingNature Genetics, 41
-
A. Casper, P. Nghiem, M. Arlt, T. Glover (2002)
ATR Regulates Fragile Site StabilityCell, 111
-
R. Paulsen, Deena Soni, Roy Wollman, Angela Hahn, M. Yee, Anna Guan, Jayne Hesley, Steven Miller, E. Cromwell, D. Solow-Cordero, T. Meyer, Karlene Cimprich (2009)
A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability.Molecular cell, 35 2
-
M. Anglana, F. Apiou, A. Bensimon, M. Debatisse (2003)
Dynamics of DNA Replication in Mammalian Somatic Cells Nucleotide Pool Modulates Origin Choice and Interorigin SpacingCell, 114
-
B. Sirbu, Frank Couch, J. Feigerle, Srividya Bhaskara, S. Hiebert, D. Cortez (2011)
Analysis of protein dynamics at active, stalled, and collapsed replication forks.Genes & development, 25 12
-
P. Brooks, J. Theruvathu (2005)
DNA adducts from acetaldehyde: implications for alcohol-related carcinogenesis.Alcohol, 35 3
-
T. Yusufzai, Xiangduo Kong, K. Yokomori, J. Kadonaga (2009)
The annealing helicase HARP is recruited to DNA repair sites via an interaction with RPA.Genes & development, 23 20
-
L. Zou, S. Elledge (2003)
Sensing DNA Damage Through ATRIP Recognition of RPA-ssDNA ComplexesScience, 300
-
M. Lopes, Cecilia Cotta-Ramusino, A. Pellicioli, G. Liberi, P. Plevani, M. Muzi-Falconi, C. Newlon, M. Foiani (2001)
The DNA replication checkpoint response stabilizes stalled replication forksNature, 412
-
Jiazhi Hu, Lei Sun, F. Shen, Yufei Chen, Yu Hua, Yang Liu, Mian Zhang, Yiren Hu, Qingsong Wang, Wei Xu, F. Sun, J. Ji, J. Murray, A. Carr, D. Kong (2012)
The Intra-S Phase Checkpoint Targets Dna2 to Prevent Stalled Replication Forks from ReversingCell, 149
-
Rodrigo Bermejo, T. Capra, Rachel Jossen, A. Colosio, Camilla Frattini, Walter Carotenuto, A. Cocito, Ylli Doksani, H. Klein, Belén Gómez-González, A. Aguilera, Y. Katou, K. Shirahige, M. Foiani (2011)
The Replication Checkpoint Protects Fork Stability by Releasing Transcribed Genes from Nuclear PoresCell, 146
-
Pablo Huertas, A. Aguilera (2003)
Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination.Molecular cell, 12 3
-
Jingsong Yuan, G. Ghosal, Junjie Chen (2009)
The annealing helicase HARP protects stalled replication forks.Genes & development, 23 20
-
Rebecca Chanoux, B. Yin, K. Urtishak, Amma Asare, C. Bassing, E. Brown (2009)
ATR and H2AX Cooperate in Maintaining Genome Stability under Replication Stress*Journal of Biological Chemistry, 284
-
Simona Negrini, V. Gorgoulis, T. Halazonetis (2010)
Genomic instability — an evolving hallmark of cancerNature Reviews Molecular Cell Biology, 11
-
A. Bester, M. Roniger, Y. Oren, M. Im, Dan Sarni, Malka Chaoat, A. Bensimon, G. Zamir, D. Shewach, B. Kerem (2011)
Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer DevelopmentCell, 145
-
Marcin Pacek, J. Walter (2004)
A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replicationThe EMBO Journal, 23
-
J. Dalgaard (2012)
Causes and consequences of ribonucleotide incorporation into nuclear DNA.Trends in genetics : TIG, 28 12
-
Lamia Wahba, J. Amon, D. Koshland, Milena Vuica-Ross (2011)
RNase H and multiple RNA biogenesis factors cooperate to prevent RNA:DNA hybrids from generating genome instability.Molecular cell, 44 6
-
Jane Kim, S. Mirkin (2013)
The balancing act of DNA repeat expansions.Current opinion in genetics & development, 23 3
-
S. Sivasubramaniam, Xuemin Sun, Yen-Ru Pan, Shaohui Wang, E. Lee (2008)
Cep164 is a mediator protein required for the maintenance of genomic stability through modulation of MDC1, RPA, and CHK1.Genes & development, 22 5
-
Rodrigo Bermejo, Mong Lai, M. Foiani (2012)
Preventing replication stress to maintain genome stability: resolving conflicts between replication and transcription.Molecular cell, 45 6
-
S. McElhinny, Dinesh Kumar, A. Clark, Danielle Watt, Brian Watts, Else-Britt Lundström, E. Johansson, A. Chabes, T. Kunkel (2010)
Genome instability due to ribonucleotide incorporation into DNANature chemical biology, 6
-
Xialu Li, J. Manley (2005)
Inactivation of the SR Protein Splicing Factor ASF/SF2 Results in Genomic InstabilityCell, 122
-
A. Chaudhuri, Yoshitami Hashimoto, Raquel Herrador, K. Neelsen, D. Fachinetti, Rodrigo Bermejo, A. Cocito, V. Costanzo, M. Lopes (2012)
Topoisomerase I poisoning results in PARP-mediated replication fork reversalNature Structural &Molecular Biology, 19
-
I. Elvers, F. Johansson, Petra Groth, K. Erixon, T. Helleday (2011)
UV stalled replication forks restart by re-priming in human fibroblastsNucleic Acids Research, 39
-
Martin Reijns, Björn Rabe, R. Rigby, P. Mill, Katy Astell, L. Lettice, S. Boyle, A. Leitch, M. Keighren, F. Kilanowski, Paul Devenney, D. Sexton, G. Grimes, I. Holt, R. Hill, Martin Taylor, K. Lawson, J. Dorin, A. Jackson (2012)
Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and DevelopmentCell, 149
-
Özlem Yüce, S. West (2012)
Senataxin, Defective in the Neurodegenerative Disorder Ataxia with Oculomotor Apraxia 2, Lies at the Interface of Transcription and the DNA Damage ResponseMolecular and Cellular Biology, 33
-
Giacomo Piccoli, Y. Katou, T. Itoh, Ryuichiro Nakato, K. Shirahige, K. Labib (2012)
Replisome stability at defective DNA replication forks is independent of S phase checkpoint kinases.Molecular cell, 45 5
-
Alexandre Maréchal, L. Zou (2013)
DNA damage sensing by the ATM and ATR kinases.Cold Spring Harbor perspectives in biology, 5 9
-
S. Ying, Sheroy Minocherhomji, Kok-Lung Chan, T. Palmai-Pallag, W. Chu, T. Wass, H. Mankouri, Y. Liu, I. Hickson (2013)
MUS81 promotes common fragile site expressionNature Cell Biology, 15
-
M. Murga, S. Campaner, A. López-Contreras, L. Toledo, Rebeca Soria, M. Montaña, L. D’Artista, Thomas Schleker, C. Guerra, Elena García, M. Barbacid, M. Hidalgo, B. Amati, O. Fernandez-Capetillo (2011)
Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumorsNature Structural &Molecular Biology, 18
-
K. Neelsen, Isabella Zanini, Raquel Herrador, M. Lopes (2013)
Oncogenes induce genotoxic stress by mitotic processing of unusual replication intermediatesThe Journal of Cell Biology, 200
-
Peter Stirling, Y. Chan, Sean Minaker, Maria Aristizabal, I. Barrett, Payal Sipahimalani, M. Kobor, P. Hieter (2012)
R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants.Genes & development, 26 2
-
Joao Matos, Miguel Blanco, S. Maslen, J. Skehel, S. West (2011)
Regulatory Control of the Resolution of DNA Recombination Intermediates during Meiosis and MitosisCell, 147
-
A. Aguilera, Tatiana García-Muse (2012)
R loops: from transcription byproducts to threats to genome stability.Molecular cell, 46 2
-
Alberto Ciccia, S. Elledge (2010)
The DNA damage response: making it safe to play with knives.Molecular cell, 40 2
-
Seetha Srinivasan, D. Dominguez-Sola, Lily Wang, O. Hyrien, J. Gautier (2013)
Cdc45 is a critical effector of myc-dependent DNA replication stress.Cell reports, 3 5
-
Debbie McIntosh, J. Blow (2012)
Dormant origins, the licensing checkpoint, and the response to replicative stresses.Cold Spring Harbor perspectives in biology, 4 10
-
Cindy Follonier, Judith Oehler, Raquel Herrador, M. Lopes (2013)
Friedreich's ataxia–associated GAA repeats induce replication-fork reversal and unusual molecular junctionsNature Structural &Molecular Biology, 20
-
K. Schlacher, N. Christ, Nicolas Siaud, A. Egashira, Hong Wu, M. Jasin (2011)
Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11Cell, 145
-
A. Helmrich, M. Ballarino, E. Nudler, L. Tora (2013)
Transcription-replication encounters, consequences and genomic instabilityNature Structural &Molecular Biology, 20
-
I. Gonzalez-Suarez, S. Gonzalo (2010)
Nurturing the genome: A-type lamins preserve genomic stability.Nucleus, 1 2
-
R. Bétous, A. Mason, R. Rambo, Carol Bansbach, Akosua Badu-Nkansah, B. Sirbu, B. Eichman, D. Cortez (2012)
SMARCAL1 catalyzes fork regression and Holliday junction migration to maintain genome stability during DNA replication.Genes & development, 26 2
-
Anja Duursma, R. Driscoll, Josh Elias, Karlene Cimprich (2013)
A role for the MRN complex in ATR activation via TOPBP1 recruitment.Molecular cell, 50 1
-
Hyungjin Kim, A. D’Andrea (2012)
Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway.Genes & development, 26 13
-
Halfdan Beck, Viola Nähse-Kumpf, M. Larsen, K. O’Hanlon, S. Patzke, C. Holmberg, Jakob Mejlvang, Anja Groth, O. Nielsen, R. Syljuåsen, C. Sørensen (2012)
Cyclin-Dependent Kinase Suppression by WEE1 Kinase Protects the Genome through Control of Replication Initiation and Nucleotide ConsumptionMolecular and Cellular Biology, 32
-
K Labib, G De Piccoli (2011)
Surviving chromosome replication: the many roles of the S-phase checkpoint pathwayPhilos. Trans. R. Soc. Lond. B, 366
-
M. Arlt, T. Wilson, T. Glover (2012)
Replication stress and mechanisms of CNV formation.Current opinion in genetics & development, 22 3
-
C. McMurray (2010)
Mechanisms of trinucleotide repeat instability during human developmentNature Reviews Genetics, 11
-
M. Lopes, M. Foiani, J. Sogo (2006)
Multiple mechanisms control chromosome integrity after replication fork uncoupling and restart at irreparable UV lesions.Molecular cell, 21 1
-
Jérôme Poli, O. Tsaponina, Laure Crabbe, A. Keszthelyi, V. Pantesco, A. Chabes, Armelle Lengronne, P. Pasero (2012)
dNTP pools determine fork progression and origin usage under replication stressThe EMBO Journal, 31
-
L. Postow, Eileen Woo, B. Chait, H. Funabiki (2009)
Identification of SMARCAL1 as a Component of the DNA Damage Response*The Journal of Biological Chemistry, 284
-
Claudia Kerzendorfer, F. Hannes, R. Colnaghi, I. Abramowicz, G. Carpenter, J. Vermeesch, M. O’Driscoll (2012)
Characterizing the functional consequences of haploinsufficiency of NELF-A (WHSC2) and SLBP identifies novel cellular phenotypes in Wolf-Hirschhorn syndrome.Human molecular genetics, 21 10
-
E. Petermann, T. Helleday (2010)
Pathways of mammalian replication fork restartNature Reviews Molecular Cell Biology, 11
-
Ildikó Hajdú, Alberto Ciccia, S. Lewis, S. Elledge (2011)
Wolf–Hirschhorn syndrome candidate 1 is involved in the cellular response to DNA damageProceedings of the National Academy of Sciences, 108
-
Yaroslava Ruzankina, David Schoppy, Amma Asare, Carolyn Clark, R. Vonderheide, E. Brown (2009)
Tissue regenerative delays and synthetic lethality in adult mice upon combined deletion of ATR and p53Nature genetics, 41
-
Y. Shi, F. Lan, Caitlin Matson, P. Mulligan, J. Whetstine, P. Cole, R. Casero, Yang Shi (2004)
Histone Demethylation Mediated by the Nuclear Amine Oxidase Homolog LSD1Cell, 119
-
M. Segurado, J. Diffley (2008)
Separate roles for the DNA damage checkpoint protein kinases in stabilizing DNA replication forks.Genes & development, 22 13
-
E. Petermann, M. Orta, N. Issaeva, N. Schultz, T. Helleday (2010)
Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and RepairMolecular Cell, 37
-
Rebecca Jones, O. Mortusewicz, O. Mortusewicz, Islam Afzal, M. Lorvellec, P. García, T. Helleday, E. Petermann (2013)
Increased replication initiation and conflicts with transcription underlie Cyclin E-induced replication stressOncogene, 32
-
J. Bartek, M. Mistrik, J. Bártková (2012)
Thresholds of replication stress signaling in cancer development and treatmentNature Structural &Molecular Biology, 19
-
A. Drusco, Y. Pekarsky, S. Costinean, A. Antenucci, L. Conti, S. Volinia, R. Aqeilan, K. Huebner, N. Zanesi (2010)
Common Fragile Site Tumor Suppressor Genes and Corresponding Mouse Models of CancerJournal of Biomedicine and Biotechnology, 2011
-
M. Chaki, R. Airik, A. Ghosh, R. Giles, Rui Chen, G. Slaats, Hui Wang, T. Hurd, Weibin Zhou, A. Cluckey, H. Gee, Gokul Ramaswami, Chen-Jei Hong, B. Hamilton, I. Červenka, R. Ganji, V. Bryja, H. Arts, J. Reeuwijk, M. Oud, S. Letteboer, R. Roepman, H. Husson, O. Ibraghimov-Beskrovnaya, Takayuki Yasunaga, G. Walz, L. Eley, J. Sayer, B. Schermer, M. Liebau, T. Benzing, S. Corre, I. Drummond, Sabine Janssen, Susan Allen, S. Natarajan, John O'Toole, M. Attanasio, S. Saunier, C. Antignac, R. Koenekoop, H. Ren, I. Lopez, A. Nayır, C. Stoetzel, H. Dollfus, R. Massoudi, J. Gleeson, S. Andreoli, D. Doherty, Anna Lindstrad, C. Golzio, N. Katsanis, L. Pape, E. Abboud, A. Al‐Rajhi, R. Lewis, H. Omran, E. Lee, Shaohui Wang, JoAnn Sekiguchi, Rudel Saunders, Colin Johnson, E. Garner, K. Vanselow, J. Andersen, J. Shlomai, G. Nurnberg, P. Nurnberg, S. Levy, A. Smogorzewska, E. Otto, F. Hildebrandt (2012)
Exome Capture Reveals ZNF423 and CEP164 Mutations, Linking Renal Ciliopathies to DNA Damage Response SignalingCell, 150
-
T. Halazonetis, V. Gorgoulis, J. Bartek (2008)
An Oncogene-Induced DNA Damage Model for Cancer DevelopmentScience, 319
-
S. Koundrioukoff, S. Carignon, H. Técher, A. Letessier, O. Brison, M. Debatisse (2013)
Stepwise Activation of the ATR Signaling Pathway upon Increasing Replication Stress Impacts Fragile Site IntegrityPLoS Genetics, 9
-
S. Jackson, J. Bartek (2009)
The DNA-damage response in human biology and diseaseNature, 461
-
MF Lavin (2013)
10.4161/rdis.25230Rare Diseases, 1
-
Ryan Ragland, Sima Patel, Rebecca Rivard, Kevin Smith, Ashley Peters, A. Bielinsky, E. Brown (2013)
RNF4 and PLK1 are required for replication fork collapse in ATR-deficient cellsGenes & Development, 27
-
I. Gonzalez-Suarez, S. Gonzalo (2010)
A-type lamins preserve genomic stability -
Claudia Kerzendorfer, R. Colnaghi, I. Abramowicz, G. Carpenter, M. O’Driscoll (2013)
Meier-Gorlin syndrome and Wolf-Hirschhorn syndrome: two developmental disorders highlighting the importance of efficient DNA replication for normal development and neurogenesis.DNA repair, 12 8
-
J Broers, C Hutchison, F Ramaekers (2004)
LaminopathiesJ. Pathol., 204
-
E. Griffith, Sarah Walker, Carol-Anne Martin, P. Vagnarelli, T. Stiff, Bertrand Vernay, Nouriya Sanna, A. Saggar, B. Hamel, W. Earnshaw, P. Jeggo, A. Jackson, M. O’Driscoll (2008)
Mutations in pericentrin cause Seckel syndrome with defective ATR-dependent DNA damage signalingNature Genetics, 40
-
J. Cobb, Lotte Bjergbaek, Kenji Shimada, C. Frei, S. Gasser (2003)
DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1The EMBO Journal, 22
-
Sandie Tuduri, Laure Crabbe, C. Conti, H. Tourrière, H. Holtgreve‐Grez, A. Jauch, V. Pantesco, J. Vos, Aubin Thomas, C. Theillet, Y. Pommier, J. Tazi, A. Coquelle, P. Pasero (2010)
Topoisomerase I suppresses genomic instability by preventing interference between replication and transcriptionNature Cell Biology, 12
-
Y. Crow, Y. Crow, A. Leitch, B. Hayward, Anna Garner, R. Parmar, E. Griffith, Manir Ali, C. Semple, J. Aicardi, R. Babul‐Hirji, C. Baumann, P. Baxter, E. Bertini, K. Chandler, D. Chitayat, D. Cau, Catherine Déry, E. Fazzi, C. Goizet, M. King, J. Klepper, D. Lacombe, G. Lanzi, H. Lyall, M. Martínez‐Frías, M. Mathieu, C. Mckeown, A. Monier, Y. Oade, O. Quarrell, C. Rittey, R. Rogers, A. Sanchis, J. Stephenson, U. Tacke, M. Till, J. Tolmie, P. Tomlin, T. Voit, B. Weschke, C. Woods, P. Lebon, D. Bonthron, C. Ponting, A. Jackson (2006)
Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infectionNature Genetics, 38
-
E. Brown, D. Baltimore (2000)
ATR disruption leads to chromosomal fragmentation and early embryonic lethality.Genes & development, 14 4
- Publisher
- Springer Journals
- Copyright
- Copyright © 2014 by Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.
- Subject
- Life Sciences; Life Sciences, general; Cell Biology; Cancer Research; Developmental Biology; Stem Cells
- ISSN
- 1465-7392
- eISSN
- 1476-4679
- DOI
- 10.1038/ncb2897
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- See Article on Publisher Site
Abstract
Defects in DNA replication, or in the pathways evolved to correct DNA replication problems, can cause genomic instability and disease. Zeman and Cimprich discuss recent advances in our understanding of the cellular responses to replication stress.
Journal
Nature Cell Biology – Springer Journals
Published: Dec 24, 2013