M. Anglana, F. Apiou, A. Bensimon, M. Debatisse (2003)
Dynamics of DNA Replication in Mammalian Somatic Cells Nucleotide Pool Modulates Origin Choice and Interorigin SpacingCell, 114
B. Sirbu, Frank Couch, J. Feigerle, Srividya Bhaskara, S. Hiebert, D. Cortez (2011)
Analysis of protein dynamics at active, stalled, and collapsed replication forks.Genes & development, 25 12
Michael Lam, Qinghua Liu, S. Elledge, J. Rosen (2004)
Chk1 is haploinsufficient for multiple functions critical to tumor suppression.Cancer cell, 6 1
Taija Hällström, Sari Jäämaa, Mia Mönkkönen, K. Peltonen, L. Andersson, R. Medema, D. Peehl, M. Laiho (2007)
Human prostate epithelium lacks Wee1A-mediated DNA damage-induced checkpoint enforcementProceedings of the National Academy of Sciences, 104
Laura Parker, H. Piwnica-Worms (1992)
Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase.Science, 257 5078
Samira Fekairi, S. Scaglione, Charly Chahwan, E. Taylor, A. Tissier, S. Coulon, M. Dong, C. Ruse, J. Yates, P. Russell, R. Fuchs, C. Mcgowan, P. Gaillard (2009)
Human SLX4 Is a Holliday Junction Resolvase Subunit that Binds Multiple DNA Repair/Recombination EndonucleasesCell, 138
Anne Carpenter, T. Jones, M. Lamprecht, C. Clarke, In Kang, O. Friman, D. Guertin, Joo Chang, Robert Lindquist, J. Moffat, P. Golland, D. Sabatini (2006)
CellProfiler: image analysis software for identifying and quantifying cell phenotypesGenome Biology, 7
H. Hirai, Y. Iwasawa, Megumu Okada, T. Arai, T. Nishibata, Makiko Kobayashi, Toshifumi Kimura, N. Kaneko, Junko Ohtani, Kazunori Yamanaka, H. Itadani, Ikuko Takahashi-Suzuki, K. Fukasawa, H. Oki, Tadahiro Nambu, Jian Jiang, T. Sakai, H. Arakawa, Toshihiro Sakamoto, T. Sagara, T. Yoshizumi, S. Mizuarai, H. Kotani (2009)
Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agentsMolecular Cancer Therapeutics, 8
P. Krutzik, G. Nolan (2006)
Fluorescent cell barcoding in flow cytometry allows high-throughput drug screening and signaling profilingNature Methods, 3
S. Lambert, Benoît Froget, A. Carr (2007)
Arrested replication fork processing: interplay between checkpoints and recombination.DNA repair, 6 7
A. López-Contreras, P. Gutierrez-Martinez, Julia Specks, Sara Rodrigo-Perez, O. Fernandez-Capetillo (2012)
An extra allele of Chk1 limits oncogene-induced replicative stress and promotes transformationThe Journal of Experimental Medicine, 209
Halfdan Beck, Viola Nähse, M. Larsen, Petra Groth, T. Clancy, M. Lees, Mette Jørgensen, T. Helleday, R. Syljuåsen, C. Sørensen (2010)
Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phaseThe Journal of Cell Biology, 188
A. Lloyd, F. Obermuller, S. Staddon, C. Barth, M. McMahon, H. Land (1997)
Cooperating oncogenes converge to regulate cyclin/cdk complexes.Genes & development, 11 5
Jérôme Poli, O. Tsaponina, Laure Crabbe, A. Keszthelyi, V. Pantesco, A. Chabes, Armelle Lengronne, P. Pasero (2012)
dNTP pools determine fork progression and origin usage under replication stressThe EMBO Journal, 31
K. Hanada, K. Hanada, Magda Budzowska, S. Davies, E. Drunen, Hideo Onizawa, H. Beverloo, A. Maas, J. Essers, I. Hickson, R. Kanaar (2007)
The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaksNature Structural &Molecular Biology, 14
Simona Negrini, V. Gorgoulis, T. Halazonetis (2010)
Genomic instability — an evolving hallmark of cancerNature Reviews Molecular Cell Biology, 11
A. Bester, M. Roniger, Y. Oren, M. Im, Dan Sarni, Malka Chaoat, A. Bensimon, G. Zamir, D. Shewach, B. Kerem (2011)
Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer DevelopmentCell, 145
Dana Branzei, M. Foiani (2010)
Maintaining genome stability at the replication forkNature Reviews Molecular Cell Biology, 11
K. Labib, Giacomo Piccoli (2011)
Surviving chromosome replication: the many roles of the S-phase checkpoint pathwayPhilosophical Transactions of the Royal Society B: Biological Sciences, 366
Jennifer Svendsen, Agata Smogorzewska, Agata Smogorzewska, M. Sowa, B. O'Connell, S. Gygi, Stephen Elledge, Stephen Elledge, J. Harper (2009)
Mammalian BTBD12/SLX4 Assembles A Holliday Junction Resolvase and Is Required for DNA RepairCell, 138
C. Sørensen, L. Hansen, J. Dziegielewski, R. Syljuåsen, Cecilia Lundin, J. Bartek, T. Helleday (2005)
The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repairNature Cell Biology, 7
Raquel Domínguez-Kelly, Yusé Martín, S. Koundrioukoff, M. Tanenbaum, V. Smits, R. Medema, M. Debatisse, R. Freire (2011)
Wee1 controls genomic stability during replication by regulating the Mus81-Eme1 endonucleaseThe Journal of Cell Biology, 194
Karlene Cimprich, D. Cortez (2008)
ATR: an essential regulator of genome integrityNature Reviews Molecular Cell Biology, 9
Davide Mantiero, A. Mackenzie, A. Donaldson, P. Zegerman (2011)
Limiting replication initiation factors execute the temporal programme of origin firing in budding yeastThe EMBO Journal, 30
D. Dimitrova, D. Gilbert (2000)
Temporally coordinated assembly and disassembly of replication factories in the absence of DNA synthesisNature Cell Biology, 2
Ivan Muñoz, Karolina Hain, A. Déclais, M. Gardiner, G. Toh, L. Sánchez-Pulido, J. Heuckmann, R. Toth, Thomas Macartney, Berina Eppink, R. Kanaar, C. Ponting, D. Lilley, J. Rouse (2009)
Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair.Molecular cell, 35 1
J. Bártková, Z. Hořejší, K. Koed, A. Krämer, F. Tort, K. Zieger, P. Guldberg, M. Sehested, J. Nesland, C. Lukas, T. Ørntoft, J. Lukas, J. Bartek (2005)
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesisNature, 434
Béatrice Roy, Claire Beuneu, Pascal Roux, Henri Buc, Geneviève Lemaire, Michel Lepoivre (1999)
Simultaneous determination of pyrimidine or purine deoxyribonucleoside triphosphates using a polymerase assay.Analytical biochemistry, 269 2
C. Lukas, Velibor Savic, Simon Bekker-Jensen, C. Doil, B. Neumann, Ronni Pedersen, Merete Grøfte, Kok-Lung Chan, I. Hickson, J. Bartek, J. Lukas (2011)
53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stressNature Cell Biology, 13
Yuko Katsuno, A. Suzuki, Kazuto Sugimura, K. Okumura, D. Zineldeen, M. Shimada, Hiroyuki Niida, T. Mizuno, F. Hanaoka, M. Nakanishi (2009)
Cyclin A–Cdk1 regulates the origin firing program in mammalian cellsProceedings of the National Academy of Sciences, 106
S. Courbet, Sophie Gay, N. Arnoult, G. Wronka, M. Anglana, O. Brison, M. Debatisse (2008)
Replication fork movement sets chromatin loop size and origin choice in mammalian cellsNature, 455
R. Syljuåsen, C. Sørensen, L. Hansen, Kasper Fugger, Cecilia Lundin, F. Johansson, T. Helleday, M. Sehested, J. Lukas, J. Bartek (2005)
Inhibition of Human Chk1 Causes Increased Initiation of DNA Replication, Phosphorylation of ATR Targets, and DNA BreakageMolecular and Cellular Biology, 25
Stine Jørgensen, I. Elvers, M. Trelle, T. Menzel, M. Eskildsen, O. Jensen, T. Helleday, K. Helin, C. Sørensen (2007)
The histone methyltransferase SET8 is required for S-phase progressionThe Journal of Cell Biology, 179
L. Vassilev, C. Tovar, Shaoqing Chen, D. Knezevic, Xiao-Wei Zhao, Hongmao Sun, D. Heimbrook, Li Chen (2006)
Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1.Proceedings of the National Academy of Sciences of the United States of America, 103 28
E. Petermann, M. Woodcock, T. Helleday (2010)
Chk1 promotes replication fork progression by controlling replication initiationProceedings of the National Academy of Sciences, 107
C. Sørensen, R. Syljuåsen (2011)
Safeguarding genome integrity: the checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replicationNucleic Acids Research, 40
J. Bártková, Nousin Rezaei, M. Liontos, Panagiotis Karakaidos, D. Kletsas, N. Issaeva, Leandros-Vassilios Vassiliou, E. Kolettas, K. Niforou, V. Zoumpourlis, M. Takaoka, H. Nakagawa, F. Tort, Kasper Fugger, F. Johansson, M. Sehested, C. Andersen, L. Dyrskjøt, T. Ørntoft, J. Lukas, C. Kittas, T. Helleday, T. Halazonetis, J. Bartek, V. Gorgoulis (2006)
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpointsNature, 444
J. Harrigan, R. Belotserkovskaya, J. Coates, D. Dimitrova, Sophie Polo, C. Bradshaw, P. Fraser, S. Jackson (2011)
Replication stress induces 53BP1-containing OPT domains in G1 cellsThe Journal of Cell Biology, 193
D. Remus, J. Diffley (2009)
Eukaryotic DNA replication control: lock and load, then fire.Current opinion in cell biology, 21 6
J. Forment, Melanie Blasius, Ilaria Guerini, S. Jackson (2011)
Structure-Specific DNA Endonuclease Mus81/Eme1 Generates DNA Damage Caused by Chk1 InactivationPLoS ONE, 6
A. López-Contreras, O. Fernandez-Capetillo (2010)
The ATR barrier to replication-born DNA damage.DNA repair, 9 12
Joao Matos, Miguel Blanco, S. Maslen, J. Skehel, S. West (2011)
Regulatory Control of the Resolution of DNA Recombination Intermediates during Meiosis and MitosisCell, 147
Chin-Lee Wu, Sandra Kirley, Hua Xiao, Yen-Shu Chuang, D. Chung, L. Zukerberg (2001)
Cables enhances cdk2 tyrosine 15 phosphorylation by Wee1, inhibits cell growth, and is lost in many human colon and squamous cancers.Cancer research, 61 19
H. Tourrière, P. Pasero (2007)
Maintenance of fork integrity at damaged DNA and natural pause sites.DNA repair, 6 7
R. Micco, M. Fumagalli, Angelo Cicalese, S. Piccinin, P. Gasparini, C. Luise, C. Schurra, M. Garrè, P. Nuciforo, A. Bensimon, R. Maestro, P. Pelicci, F. Fagagna (2006)
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replicationNature, 444
Sandie Tuduri, Laure Crabbe, C. Conti, H. Tourrière, H. Holtgreve‐Grez, A. Jauch, V. Pantesco, J. Vos, Aubin Thomas, C. Theillet, Y. Pommier, J. Tazi, A. Coquelle, P. Pasero (2010)
Topoisomerase I suppresses genomic instability by preventing interference between replication and transcriptionNature Cell Biology, 12
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Published: Aug 21, 2012
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