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Characterization of Memory Profile in Subjects with Amnestic Mild Cognitive Impairment

Characterization of Memory Profile in Subjects with Amnestic Mild Cognitive Impairment Different aspects of episodic long-term, short-term and implicit long-term memory were investigated in subjects who strictly fulfilled the criteria for the amnestic form of Mild Cognitive Impairment (a-MCI). Results showed normal short-term memory abilities in these subjects, while each of the episodic long-term memory indices explored showed poorer results in a-MCI subjects with respect to normal controls. Although some episodic memory functions were relatively well preserved, others appeared to have deteriorated to a level comparable to that of mild AD patients. The finding of an extensive impairment of all memory functions depending on hippocampal structures in a population with a high risk of developing dementia is strongly supportive of the hypothesis that a pure amnesic syndrome characterizes the preclinical phase of AD. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Clinical and Experimental Neuropsychology Taylor & Francis

Characterization of Memory Profile in Subjects with Amnestic Mild Cognitive Impairment

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References (53)

Publisher
Taylor & Francis
Copyright
Copyright Taylor & Francis Group, LLC
ISSN
1744-411x
eISSN
1380-3395
DOI
10.1080/13803390490919317
pmid
16273685
Publisher site
See Article on Publisher Site

Abstract

Different aspects of episodic long-term, short-term and implicit long-term memory were investigated in subjects who strictly fulfilled the criteria for the amnestic form of Mild Cognitive Impairment (a-MCI). Results showed normal short-term memory abilities in these subjects, while each of the episodic long-term memory indices explored showed poorer results in a-MCI subjects with respect to normal controls. Although some episodic memory functions were relatively well preserved, others appeared to have deteriorated to a level comparable to that of mild AD patients. The finding of an extensive impairment of all memory functions depending on hippocampal structures in a population with a high risk of developing dementia is strongly supportive of the hypothesis that a pure amnesic syndrome characterizes the preclinical phase of AD.

Journal

Journal of Clinical and Experimental NeuropsychologyTaylor & Francis

Published: Nov 1, 2005

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