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References (80)
-
T. Holyoake, Xiaoyan Jiang, M. Drummond, A. Eaves, C. Eaves (2002)
Elucidating critical mechanisms of deregulated stem cell turnover in the chronic phase of chronic myeloid leukemiaLeukemia, 16
-
W. Terpstra, Ploemacher, Arie Prins, K. Lom, K. Pouwels, A. Wognum, G. Wagemaker, B. Lowenberg, J. Wielenga (1996)
Fluorouracil selectively spares acute myeloid leukemia cells with long-term growth abilities in immunodeficient mice and in culture.Blood, 88 6
-
V. Donnenberg, A. Donnenberg (2005)
Multiple Drug Resistance in Cancer Revisited: The Cancer Stem Cell HypothesisThe Journal of Clinical Pharmacology, 45
-
M. Guzman, C. Jordan (2004)
Considerations for targeting malignant stem cells in leukemia.Cancer control : journal of the Moffitt Cancer Center, 11 2
-
R. Pardal, M. Clarke, S. Morrison (2003)
Applying the principles of stem-cell biology to cancerNature Reviews Cancer, 3
-
J. Cairns (2002)
Somatic stem cells and the kinetics of mutagenesis and carcinogenesisProceedings of the National Academy of Sciences of the United States of America, 99
-
M. Al-Hajj, M. Wicha, Adalberto Benito-Hernández, S. Morrison, M. Clarke (2003)
Prospective identification of tumorigenic breast cancer cellsProceedings of the National Academy of Sciences of the United States of America, 100
-
D. Bonnet, E. Warren, P. Greenberg, J. Dick, S. Riddell (1999)
CD8(+) minor histocompatibility antigen-specific cytotoxic T lymphocyte clones eliminate human acute myeloid leukemia stem cells.Proceedings of the National Academy of Sciences of the United States of America, 96 15
-
S. Barnett, L. Robertson, D. Graham, D. Allan, R. Rampling (1998)
Oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells transformed with c-myc and H-ras form high-grade glioma after stereotactic injection into the rat brain.Carcinogenesis, 19 9
-
Y. Guan, B. Gerhard, D. Hogge (2003)
Detection, isolation, and stimulation of quiescent primitive leukemic progenitor cells from patients with acute myeloid leukemia (AML).Blood, 101 8
-
C. Jamieson, L. Ailles, S. Dylla, M. Muijtjens, Carol Jones, J. Zehnder, J. Gotlib, Kevin Li, M. Manz, A. Keating, C. Sawyers, I. Weissman (2004)
Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML.The New England journal of medicine, 351 7
-
M. Tallman, D. Gilliland, J. Rowe, R. Lurie (2005)
Drug therapy for acute myeloid leukemia.Blood, 106 4
-
M. Noble, K. Murray (1984)
Purified astrocytes promote the in vitro division of a bipotential glial progenitor cell.The EMBO Journal, 3
-
R. Clarke (2005)
Isolation and characterization of human mammary stem cellsCell Proliferation, 38
-
M. Al-Hajj, M. Clarke (2004)
Self-renewal and solid tumor stem cellsOncogene, 23
-
(2005)
The development of imatinib as a therapeutic agent for chronic myeloid leukemia -
M. Feuring‐Buske, A. Frankel, Richard Alexander, B. Gerhard, D. Hogge (2002)
A diphtheria toxin-interleukin 3 fusion protein is cytotoxic to primitive acute myeloid leukemia progenitors but spares normal progenitors.Cancer research, 62 6
-
B. Huntly, Hirokazu Shigematzu, K. Deguchi, Benjamin Lee, S. Mizuno, Nicky Duclos, R. Rowan, Sonia Amaral, D. Curley, I. Williams, K. Akashi, Gary Gilliland (2004)
MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors.Cancer cell, 6 6
-
Suling Liu, G. Dontu, M. Wicha (2005)
Mammary stem cells, self-renewal pathways, and carcinogenesisBreast Cancer Research, 7
-
B. Reynolds, S. Weiss (1992)
Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system.Science, 255 5052
-
S. Shmelkov, Ryan Clair, D. Lyden, S. Rafii (2005)
AC133/CD133/Prominin-1.The international journal of biochemistry & cell biology, 37 4
-
M. Gottesman, T. Fojo, S. Bates (2002)
Multidrug resistance in cancer: role of ATP–dependent transportersNature Reviews Cancer, 2
-
M. Narita, S. Lowe (2005)
Senescence comes of ageNature Medicine, 11
-
B. Chiasson, V. Tropepe, C. Morshead, D. Kooy (1999)
Adult Mammalian Forebrain Ependymal and Subependymal Cells Demonstrate Proliferative Potential, but only Subependymal Cells Have Neural Stem Cell CharacteristicsThe Journal of Neuroscience, 19
-
J. Shizuru, R. Negrin, I. Weissman (2005)
Hematopoietic stem and progenitor cells: clinical and preclinical regeneration of the hematolymphoid system.Annual review of medicine, 56
-
C. Cobaleda, N. Gutiérrez-Cianca, J. Pérez-Losada, Teresa Flores, Ramón García-Sanz, Marcos González, I. Sánchez-García (2000)
A primitive hematopoietic cell is the target for the leukemic transformation in human philadelphia-positive acute lymphoblastic leukemia.Blood, 95 3
-
M. Guzman, R. Rossi, Lilliana Karnischky, Xiaojie Li, Derick Peterson, D. Howard, C. Jordan (2005)
The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells.Blood, 105 11
-
T. Lapidot, C. Sirard, J. Vormoor, B. Murdoch, T. Hoang, J. Cáceres-Cortés, M. Minden, B. Paterson, M. Caligiuri, J. Dick (1994)
A cell initiating human acute myeloid leukaemia after transplantation into SCID miceNature, 367
-
Ömer Yilmaz, R. Valdez, Brian Theisen, Wei Guo, D. Ferguson, Hong Wu, S. Morrison (2006)
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cellsNature, 441
-
A. Rhenen, N. Feller, A. Kelder, A. Westra, E. Rombouts, S. Zweegman, M. Pol, Q. Waisfisz, G. Ossenkoppele, G. Schuurhuis (2005)
High Stem Cell Frequency in Acute Myeloid Leukemia at Diagnosis Predicts High Minimal Residual Disease and Poor SurvivalClinical Cancer Research, 11
-
Sheila Singh, C. Hawkins, I. Clarke, J. Squire, J. Bayani, T. Hide, R. Henkelman, M. Cusimano, M. Cusimano, P. Dirks (2004)
Identification of human brain tumour initiating cellsNature, 432
-
C. Jordan (2005)
Targeting the most critical cells: approaching leukemia therapy as a problem in stem cell biologyNature Clinical Practice Oncology, 2
-
C. Jordan, M. Guzman (2004)
Mechanisms controlling pathogenesis and survival of leukemic stem cellsOncogene, 23
-
J. Cortes, S. O'brien, H. Kantarjian (2004)
Discontinuation of imatinib therapy after achieving a molecular response.Blood, 104 7
-
R. Seaberg, D. Kooy (2003)
Stem and progenitor cells: the premature desertion of rigorous definitionsTrends in Neurosciences, 26
-
M. Shackleton, F. Vaillant, K. Simpson, J. Stingl, G. Smyth, M. Asselin-Labat, Li Wu, G. Lindeman, J. Visvader (2006)
Generation of a functional mammary gland from a single stem cellNature, 439
-
A. Cozzio, E. Passegué, P. Ayton, H. Karsunky, M. Cleary, I. Weissman (2003)
Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors.Genes & development, 17 24
-
M. Al-Hajj, M. Becker, M. Wicha, I. Weissman, M. Clarke (2004)
Therapeutic implications of cancer stem cells.Current opinion in genetics & development, 14 1
-
T. Reya, S. Morrison, M. Clarke, I. Weissman (2001)
Stem cells, cancer, and cancer stem cellsNature, 414
-
A. Groves, A. Groves, S. Barnett, R. Franklin, A. Crang, Margot Mayer, W. Blakemore, M. Noble (1993)
Repair of demyelinated lesions by transplantation of purified 0-2A progenitor cellsNature, 362
-
M. Rao, M. Mayer-Proschel (1997)
Glial-restricted precursors are derived from multipotent neuroepithelial stem cells.Developmental biology, 188 1
-
P. Fialkow, S. Gartler, A. Yoshida (1967)
Clonal origin of chronic myelocytic leukemia in man.Proceedings of the National Academy of Sciences of the United States of America, 58 4
-
J. Stingl, P. Eirew, Ian Ricketson, M. Shackleton, F. Vaillant, D. Choi, H. Li, C. Eaves (2006)
Purification and unique properties of mammary epithelial stem cellsNature, 439
-
B. Reynolds, W. Tetzlaff, S. Weiss (1992)
A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes, 12
-
F. Behbod, J. Rosen (2005)
Will cancer stem cells provide new therapeutic targets?Carcinogenesis, 26 4
-
Sheila Singh, I. Clarke, T. Hide, P. Dirks (2004)
Cancer stem cells in nervous system tumorsOncogene, 23
-
C. Jordan (2002)
Unique molecular and cellular features of acute myelogenous leukemia stem cellsLeukemia, 16
-
N. Uchida, D. Buck, D. He, Michael Reitsma, M. Masek, Thinh Phan, A. Tsukamoto, F. Gage, I. Weissman (2000)
Direct isolation of human central nervous system stem cells.Proceedings of the National Academy of Sciences of the United States of America, 97 26
-
M. Copland, A. Hamilton, Lucy Elrick, J. Baird, E. Allan, N. Jordanides, M. Barow, J. Mountford, T. Holyoake (2006)
Dasatinib (BMS-354825) targets an earlier progenitor population than imatinib in primary CML but does not eliminate the quiescent fraction.Blood, 107 11
-
A. Castor, L. Nilsson, Ingbritt Åstrand‐Grundström, M. Buitenhuis, Carole Ramirez, K. Anderson, B. Strömbeck, S. Garwicz, A. Békássy, K. Schmiegelow, B. Lausen, P. Hokland, S. Lehmann, G. Juliusson, B. Johansson, S. Jacobsen (2005)
Distinct patterns of hematopoietic stem cell involvement in acute lymphoblastic leukemiaNature Medicine, 11
-
J. Cortes, H. Kantarjian (2005)
New targeted approaches in chronic myeloid leukemia.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 23 26
-
S. Graham, H. Jørgensen, E. Allan, C. Pearson, M. Alcorn, L. Richmond, T. Holyoake (2002)
Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro.Blood, 99 1
-
Jean Wang, J. Dick (2005)
Cancer stem cells: lessons from leukemia.Trends in cell biology, 15 9
-
J. Dick (2005)
Acute Myeloid Leukemia Stem CellsAnnals of the New York Academy of Sciences, 1044
-
M. Guzman, S. Neering, D. Upchurch, B. Grimes, D. Howard, D. Rizzieri, S. Luger, C. Jordan (2001)
Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells.Blood, 98 8
-
N. Feller, M. Pol, A. Stijn, G. Weijers, A. Westra, B. Evertse, G. Ossenkoppele, G. Schuurhuis (2004)
MRD parameters using immunophenotypic detection methods are highly reliable in predicting survival in acute myeloid leukaemiaLeukemia, 18
-
R. Larson, E. Sievers, E. Stadtmauer, B. Löwenberg, E. Estey, H. Dombret, M. Theobald, D. Voliotis, J. Bennett, M. Richie, L. Leopold, M. Berger, M. Sherman, M. Loken, J. Dongen, I. Bernstein, F. Appelbaum (2005)
Final report of the efficacy and safety of gemtuzumab ozogamicin (Mylotarg) in patients with CD33‐positive acute myeloid leukemia in first recurrenceCancer, 104
-
W. Woodward, Mercy Chen, F. Behbod, J. Rosen (2005)
On mammary stem cellsJournal of Cell Science, 118
-
Yong Wang, B. Schulte, A. LaRue, M. Ogawa, Daohong Zhou (2006)
Total body irradiation selectively induces murine hematopoietic stem cell senescence.Blood, 107 1
-
T. Holyoake, Xiaoyan Jiang, C. Eaves, A. Eaves (1999)
Isolation of a highly quiescent subpopulation of primitive leukemic cells in chronic myeloid leukemia.Blood, 94 6
-
S. Lowe, E. Cepero, G. Evan (2004)
Intrinsic tumour suppressionNature, 432
-
J. Green (2003)
Mouse models of human breast cancer: evolution or convolution?Breast Cancer Research : BCR, 5
-
M. Kondo, A. Wagers, M. Manz, Susan Prohaska, D. Scherer, G. Beilhack, J. Shizuru, I. Weissman (2003)
Biology of hematopoietic stem cells and progenitors: implications for clinical application.Annual review of immunology, 21
-
C. Cox, R. Evely, A. Oakhill, D. Pamphilon, N. Goulden, A. Blair (2004)
Characterization of acute lymphoblastic leukemia progenitor cells.Blood, 104 9
-
C. Jordan, D. Upchurch, S. Szilvassy, M. Guzman, D. Howard, AL Pettigrew, T. Meyerrose, R. Rossi, B. Grimes, D. Rizzieri, S. Luger, G. Phillips (2000)
The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cellsLeukemia, 14
-
Qing Xu, S. Simpson, T. Scialla, A. Bagg, M. Carroll (2003)
Survival of acute myeloid leukemia cells requires PI3 kinase activation.Blood, 102 3
-
M. Guzman, C. Swiderski, D. Howard, B. Grimes, R. Rossi, S. Szilvassy, C. Jordan (2002)
Preferential induction of apoptosis for primary human leukemic stem cellsProceedings of the National Academy of Sciences of the United States of America, 99
-
D. Taussig, D. Pearce, C. Simpson, A. Rohatiner, T. Lister, G. Kelly, Jennifer Luongo, G. Danet-Desnoyers, D. Bonnet (2005)
Hematopoietic stem cells express multiple myeloid markers: implications for the origin and targeted therapy of acute myeloid leukemia.Blood, 106 13
-
P. Hamann, L. Hinman, I. Hollander, C. Beyer, Delores Lindh, Ryan Holcomb, W. Hallett, H. Tsou, J. Upeslacis, D. Shochat, A. Mountain, D. Flowers, I. Bernstein (2002)
Gemtuzumab ozogamicin, a potent and selective anti-CD33 antibody-calicheamicin conjugate for treatment of acute myeloid leukemia.Bioconjugate chemistry, 13 1
-
A. Krivtsov, David Twomey, Zhaohui Feng, M. Stubbs, Yingzi Wang, Joerg Faber, J. Levine, Jing Wang, W. Hahn, D. Gilliland, T. Golub, S. Armstrong (2006)
Transformation from committed progenitor to leukaemia stem cell initiated by MLL–AF9Nature, 442
-
M. Dean, T. Fojo, S. Bates (2005)
Tumour stem cells and drug resistanceNature Reviews Cancer, 5
-
R. Galli, Elena Binda, U. Orfanelli, B. Cipelletti, A. Gritti, Simona Vitis, R. Fiocco, C. Foroni, F. DiMeco, A. Vescovi (2004)
Isolation and Characterization of Tumorigenic, Stem-like Neural Precursors from Human GlioblastomaCancer Research, 64
-
B. Löwenberg, P. Sonneveld (1998)
Resistance to chemotherapy in acute leukemiaCurrent Opinion in Oncology, 10
-
M. Rao, M. Noble, M. Mayer-Pröschel (1998)
A tripotential glial precursor cell is present in the developing spinal cord.Proceedings of the National Academy of Sciences of the United States of America, 95 7
-
I. Weissman (2000)
Stem Cells Units of Development, Units of Regeneration, and Units in EvolutionCell, 100
-
D. Bonnet, J. Dick (1997)
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cellNature Medicine, 3
-
A. Meng, Yong Wang, G. Zant, Daohong Zhou (2003)
Ionizing radiation and busulfan induce premature senescence in murine bone marrow hematopoietic cells.Cancer research, 63 17
-
Sheila Singh, I. Clarke, Mizuhiko Terasaki, Victoria Bonn, C. Hawkins, J. Squire, P. Dirks (2003)
Identification of a cancer stem cell in human brain tumors.Cancer research, 63 18
-
Qing Xu, James Thompson, M. Carroll (2005)
mTOR regulates cell survival after etoposide treatment in primary AML cells.Blood, 106 13
-
Yi Li, J. Rosen (2005)
Stem/Progenitor Cells in Mouse Mammary Gland Development and Breast CancerJournal of Mammary Gland Biology and Neoplasia, 10
- Publisher
- The New England Journal of Medicine
- Copyright
- Copyright © 2006 Massachusetts Medical Society. All rights reserved.
- ISSN
- 0028-4793
- eISSN
- 1533-4406
- DOI
- 10.1056/NEJMra061808
- pmid
- 16990388
- Publisher site
- See Article on Publisher Site
Abstract
This review describes cancer stem cells, a topic of considerable biologic and clinical interest in oncology.
Journal
The New England Journal of Medicine – The New England Journal of Medicine
Published: Sep 21, 2006