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Lymphatic Mapping and Sentinel Node Biopsy in Breast Cancer

Lymphatic Mapping and Sentinel Node Biopsy in Breast Cancer To the Editor. —The study by Dr Albertini and colleagues1 confirms our sentinel node hypothesis in breast cancer. Since our group began investigating the sentinel node technique for breast cancer 5 years ago, we have performed nearly 400 mapping procedures using isosulfan blue dye to identify the first axillary lymph node draining a primary breast cancer,2,3 and have abandoned routine axillary lymph node dissection. As reported in a summary of our last 100 cases, dye-based mapping in our hands has reached an accuracy of 100%, with a 93% rate of sentinel node detection.4 Thus, the authors' comment, "Previous studies have used either the vital blue dye or the radiocolloid alone, with lower success rates reported," is not correct. In addition, the use of preoperative lymphoscintigraphy for inner-quadrant lesions has increased our detection rate even further. Although we have started to evaluate the combined use of blue dye http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Lymphatic Mapping and Sentinel Node Biopsy in Breast Cancer

Giuliano, Armando E.
JAMA , Volume 277 (10) – Mar 12, 1997
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Lymphatic Mapping and Sentinel Node Biopsy in Breast Cancer

Abstract



To the Editor.
—The study by Dr Albertini and colleagues1 confirms our sentinel node hypothesis in breast cancer. Since our group began investigating the sentinel node technique for breast cancer 5 years ago, we have performed nearly 400 mapping procedures using isosulfan blue dye to identify the first axillary lymph node draining a primary breast cancer,2,3 and have abandoned routine axillary lymph node dissection. As reported in a summary of our last 100...
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References (3)

Publisher
American Medical Association
Copyright
Copyright © 1997 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1997.03540340025024
Publisher site
See Article on Publisher Site

Abstract

To the Editor. —The study by Dr Albertini and colleagues1 confirms our sentinel node hypothesis in breast cancer. Since our group began investigating the sentinel node technique for breast cancer 5 years ago, we have performed nearly 400 mapping procedures using isosulfan blue dye to identify the first axillary lymph node draining a primary breast cancer,2,3 and have abandoned routine axillary lymph node dissection. As reported in a summary of our last 100 cases, dye-based mapping in our hands has reached an accuracy of 100%, with a 93% rate of sentinel node detection.4 Thus, the authors' comment, "Previous studies have used either the vital blue dye or the radiocolloid alone, with lower success rates reported," is not correct. In addition, the use of preoperative lymphoscintigraphy for inner-quadrant lesions has increased our detection rate even further. Although we have started to evaluate the combined use of blue dye

Journal

JAMA – American Medical Association

Published: Mar 12, 1997

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