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SUPPL. 000 From the Department of Psychiatry (Head: Prof. C. Perris, M.D.), University of Umel, Umel, and Department o f Pharmacology (Head: Prof. A. Carlsson, M.D.), University of Gothenburg, Gothenburg, Sweden. VISUAL AVERAGED EVOKED RESPONSES (AER) AND MONOAMINE METABOLITES I N CEREBROSPINAL FLUID (CSF) C.G. Gottfries, C. Perris & B.E. Roos Observations by Goodwin et al. (1963) seem t o lend support to the hypothesis that a positive relationship may exist between the level of homovanillic acid (HVA) in CSF and the amplitude of visual AER. Perris (1974)) in a Results from our own laboratory (Muttsson 6â psychotic patient suffering from Addisonâs disease, who has been studied longitudinally, point in the same direction. Moreover a shortening of latencies, especially as concerns the first three peaks, has also been observed. No investigations have been published so far concerning the relationship between AER and 5 -hydroxyindoleacetic acid (5-HIAA). We here present some preliminary findings concerning a possible relationship between HVA and 5-HIAA levels in CSF and scme characteristics of visual AER in man. PATIENTS AND METHODS Twelve in-patients, four males and eight females aged 22-69 years, suffering from various psychiatric syndromes were included in the study. Since the aim of
Acta Psychiatrica Scandinavica – Wiley
Published: Nov 1, 1974
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