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5-Hydroxyindoleacetic Acid and Homovanillic Acid in Cerebrospinal Fluid of Patients with Neurological Diseases

5-Hydroxyindoleacetic Acid and Homovanillic Acid in Cerebrospinal Fluid of Patients with... The patients with Parkinson’s syndrome and multiple sclerosis show lower levels of HVA in CSF than most other patients. The latter group also has low levels of 5-HIAA. Hydrocephalus is generally supposed to have high 5-HIAA. Our study with normotensive hydrocephalus shows that these patients have normal levels. Decrease in HVA is found in spinal cord lesions with restricted flow, as has been pointed out by Curzon et al. Low values of 5-HIAA are seen in patients with transverse lesions presumably due to disappearance of the spinal portion of 5-HIAA. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Neurology Karger

5-Hydroxyindoleacetic Acid and Homovanillic Acid in Cerebrospinal Fluid of Patients with Neurological Diseases

Johansson, Barbro; Roos, Björn-Erik
European Neurology , Volume 11 (1): 9 – Jan 1, 1974
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Publisher
Karger
Copyright
© 1974 S. Karger AG, Basel
ISSN
0014-3022
eISSN
1421-9913
DOI
10.1159/000114304
Publisher site
See Article on Publisher Site

Abstract

The patients with Parkinson’s syndrome and multiple sclerosis show lower levels of HVA in CSF than most other patients. The latter group also has low levels of 5-HIAA. Hydrocephalus is generally supposed to have high 5-HIAA. Our study with normotensive hydrocephalus shows that these patients have normal levels. Decrease in HVA is found in spinal cord lesions with restricted flow, as has been pointed out by Curzon et al. Low values of 5-HIAA are seen in patients with transverse lesions presumably due to disappearance of the spinal portion of 5-HIAA.

Journal

European Neurology – Karger

Published: Jan 1, 1974

Keywords: 5-HIAA; HVA; CSF; Multiple sclerosis; Parkinsonism; Hydrocephalus

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