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- Publisher
- Springer Journals
- Copyright
- Copyright © 2005 by Nature Publishing Group
- Subject
- Medicine & Public Health; Medicine/Public Health, general; Endocrinology
- ISSN
- 1759-5029
- eISSN
- 1745-8374
- DOI
- 10.1038/ncpendmet0023
- Publisher site
- See Article on Publisher Site
Abstract
Isoenzymes of 11[beta]-hydroxysteroid dehydrogenase affect the tissue-specific interconversion of cortisone and cortisol. In rodents, selective inhibitors of these enzymes improve insulin sensitivity, and we await clinical trials to test whether such drugs can be “magic bullets” to treat type 2 diabetes and the metabolic syndrome.
Journal
Nature Reviews Endocrinology – Springer Journals
Published: Dec 1, 2005