Access the full text.
Sign up today, get DeepDyve free for 14 days.
K. Mukai, K. Matsuoka, C. Taya, Hidenori Suzuki, H. Yokozeki, K. Nishioka, K. Hirokawa, Maki Etori, M. Yamashita, Toshiyuki Kubota, Y. Minegishi, H. Yonekawa, H. Karasuyama (2005)
Basophils play a critical role in the development of IgE-mediated chronic allergic inflammation independently of T cells and mast cells.Immunity, 23 2
Y. Tsujimura, K. Obata, K. Mukai, H. Shindou, M. Yoshida, H. Nishikado, Y. Kawano, Y. Minegishi, Takao Shimizu, H. Karasuyama (2008)
Basophils play a pivotal role in immunoglobulin-G-mediated but not immunoglobulin-E-mediated systemic anaphylaxis.Immunity, 28 4
T. Ohteki, K. Suzue, C. Maki, T. Ota, S. Koyasu (2001)
Critical role of IL-15–IL-15R for antigen-presenting cell functions in the innate immune responseNature Immunology, 2
T. Yoshimoto (1999)
Interleukin-18 (IL-18), although anti-allergic when administered with IL-12, stimulates IL-4 and histamine release by basophils, 96
C. Sokol, G. Barton, A. Farr, R. Medzhitov (2008)
A mechanism for the initiation of allergen-induced T helper type 2 responsesNature Immunology, 9
M. Yamaguchi, C. Lantz, H. Oettgen, I. Katona, Tony Fleming, I. Miyajima, J. Kinet, S. Galli (1997)
IgE Enhances Mouse Mast Cell FcεRI Expression In Vitro and In Vivo: Evidence for a Novel Amplification Mechanism in IgE-dependent ReactionsThe Journal of Experimental Medicine, 185
B. Min (2008)
Basophils: what they 'can do' versus what they 'actually do'Nature Immunology, 9
Keunhee Oh, Tao Shen, G. Gros, B. Min (2007)
Induction of Th2 type immunity in a mouse system reveals a novel immunoregulatory role of basophils.Blood, 109 7
K. Nakanishi, T. Yoshimoto, H. Tsutsui, H. Okamura (2001)
Interleukin-18 regulates both Th1 and Th2 responses.Annual review of immunology, 19
J. Hu‐Li, C. Pannetier, L. Guo, M. Löhning, H. Gu, C. Watson, M. Assenmacher, Andreas Radbruch, W. Paul (2001)
Regulation of expression of IL-4 alleles: analysis using a chimeric GFP/IL-4 gene.Immunity, 14 1
T. Yoshimoto, W. Paul (1994)
CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3The Journal of Experimental Medicine, 179
T. Yoshimoto, T. Yoshimoto, K. Yasuda, J. Mizuguchi, K. Nakanishi (2007)
IL-27 Suppresses Th2 Cell Development and Th2 Cytokines Production from Polarized Th2 Cells: A Novel Therapeutic Way for Th2-Mediated Allergic Inflammation1The Journal of Immunology, 179
M. Mack, Martin Schneider, Cordula Moll, J. Cihak, H. Brühl, J. Ellwart, M. Hogarth, M. Stangassinger, D. Schlöndorff (2005)
Identification of Antigen-Capturing Cells as Basophils1The Journal of Immunology, 174
B. Min, G. Gros, W. Paul (2006)
Basophils: A Potential Liaison between Innate and Adaptive Immunity.Allergology international : official journal of the Japanese Society of Allergology, 55 2
Y. Kondo, T. Yoshimoto, K. Yasuda, S. Futatsugi-Yumikura, M. Morimoto, N. Hayashi, T. Hoshino, J. Fujimoto, K. Nakanishi (2008)
Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system.International immunology, 20 6
T. Koshino, Y. Arai, Y. Miyamoto, Y. Sano, M. Itami, S. Teshima, K. Hirai, T. Takaishi, K. Ito, Y. Morita (1996)
Airway basophil and mast cell density in patients with bronchial asthma: relationship to bronchial hyperresponsiveness.The Journal of asthma : official journal of the Association for the Care of Asthma, 33 2
B. Min, W. Paul (2008)
Basophils and type 2 immunityCurrent Opinion in Hematology, 15
I. Caramalho, Thiago Lopes-Carvalho, D. Ostler, S. Zelenay, M. Haury, J. Demengeot (2003)
Regulatory T Cells Selectively Express Toll-like Receptors and Are Activated by LipopolysaccharideThe Journal of Experimental Medicine, 197
C. Lantz, M. Yamaguchi, H. Oettgen, Ildy Katona, Ichiro Miyajima, J. Kinet, Stephen Galli (1997)
IgE regulates mouse basophil Fc epsilon RI expression in vivo.Journal of immunology, 158 6
CS Lantz (1997)
IgE regulates mouse basophil FcεRI expression in vivoJ. Immunol., 158
S. Galli, J. Kalesnikoff, M. Grimbaldeston, A. Piliponsky, Cara Williams, M. Tsai (2005)
Mast cells as "tunable" effector and immunoregulatory cells: recent advances.Annual review of immunology, 23
R. Seder, W. Paul (1994)
Acquisition of lymphokine-producing phenotype by CD4+ T cells.Annual review of immunology, 12
B. Sullivan, R. Locksley (2009)
Basophils: a nonredundant contributor to host immunity.Immunity, 30 1
I. Adcock, G. Caramori, K. Chung (2008)
New targets for drug development in asthmaThe Lancet, 372
J. Gauchat, S. Henchoz, G. Mazzei, J. Aubry, T. Brunner, H. Blasey, P. Life, D. Talabot, L. Flores-Romo, Jeff Thompson, K. Kishi, J. Butterfield, C. Dahinden, J. Bonnefoy (1993)
Induction of human IgE synthesis in B cells by mast cells and basophilsNature, 365
K. Okubo, T. Nagakura (2008)
Anti-IgE antibody therapy for Japanese cedar pollinosis: omalizumab update.Allergology international : official journal of the Japanese Society of Allergology, 57 3
B. Min, M. Prout, J. Hu‐Li, Jinfang Zhu, Dragana Jankovic, E. Morgan, J. Urban, A. Dvorak, F. Finkelman, G. Legros, W. Paul (2004)
Basophils Produce IL-4 and Accumulate in Tissues after Infection with a Th2-inducing ParasiteThe Journal of Experimental Medicine, 200
M. Löhning, A. Stroehmann, A. Coyle, J. Grogan, S. Lin, J. Gutiérrez-Ramos, D. Levinson, Andreas Radbruch, T. Kamradt (1998)
T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function.Proceedings of the National Academy of Sciences of the United States of America, 95 12
T. Yoshimoto, H. Tsutsui, K. Tominaga, K. Hoshino, H. Okamura, Shizuo Akira, W. Paul, Kenji Nakanishi (1999)
IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils.Proceedings of the National Academy of Sciences of the United States of America, 96 24
K. Nakanishi, T. Yoshimoto, H. Tsutsui, H. Okamura (2001)
Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu.Cytokine & growth factor reviews, 12 1
S. Nakae, M. Iikura, H. Suto, H. Akiba, D. Umetsu, R. DeKruyff, H. Saito, S. Galli (2007)
TIM-1 and TIM-3 enhancement of Th2 cytokine production by mast cells.Blood, 110 7
D. Voehringer, K. Shinkai, R. Locksley (2004)
Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production.Immunity, 20 3
S. Saini, A. Klion, S. Holland, R. Hamilton, B. Bochner, D. MacGlashan (2000)
The relationship between serum IgE and surface levels of FcϵR on human leukocytes in various diseases: Correlation of expression with FcϵRI on basophils but not on monocytes or eosinophilsThe Journal of Allergy and Clinical Immunology, 106
T. Kawakami, S. Galli (2002)
Regulation of mast-cell and basophil function and survival by IgENature Reviews Immunology, 2
Y. Arinobu, Hiromi Iwasaki, Hiromi Iwasaki, M. Gurish, S. Mizuno, H. Shigematsu, Hidetoshi Ozawa, D. Tenen, K. Austen, K. Akashi (2005)
Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis.Proceedings of the National Academy of Sciences of the United States of America, 102 50
H. Kosaka, T. Yoshimoto, T. Yoshimoto, J. Fujimoto, K. Nakanishi (2008)
Interferon-γ is a therapeutic target molecule for prevention of postoperative adhesion formationNature Medicine, 14
K. Verbruggen, P. Cauwenberge, C. Bachert (2008)
Anti-IgE for the Treatment of Allergic Rhinitis – and Eventually Nasal Polyps?International Archives of Allergy and Immunology, 148
L. Bradley, S. Watson, S. Swain (1994)
Entry of naive CD4 T cells into peripheral lymph nodes requires L- selectinThe Journal of Experimental Medicine, 180
Y. Sasaki, T. Yoshimoto, H. Maruyama, T. Tegoshi, N. Ohta, N. Arizono, K. Nakanishi (2005)
IL-18 with IL-2 protects against Strongyloides venezuelensis infection by activating mucosal mast cell–dependent type 2 innate immunityThe Journal of Experimental Medicine, 202
C. Ohnmacht, D. Voehringer (2009)
Basophil effector function and homeostasis during helminth infection.Blood, 113 12
H. Eisen, M. Carsten, S. Belman (1954)
Studies of hypersensitivity to low molecular weight substances. III. The 2,4-dinitrophenyl group as a determinant in the preciptin reaction.Journal of immunology, 73 5
Anne-Marie Irani, Candice Huang, H. Xia, C. Kepley, Ala' Nafie, El Fouda, Shirley Craig, B. Zweiman, L. Schwartz (1998)
Immunohistochemical detection of human basophils in late-phase skin reactions.The Journal of allergy and clinical immunology, 101 3
Andrea Denzel, U. Maus, M. Gomez, Cordula Moll, M. Niedermeier, C. Winter, R. Maus, S. Hollingshead, D. Briles, L. Kunz-Schughart, Yvonne Talke, M. Mack (2008)
Basophils enhance immunological memory responsesNature Immunology, 9
J. Reimer, S. Magnusson, M. Juremalm, G. Nilsson, G. Nilsson, L. Hellman, S. Wernersson (2006)
Isolation of transcriptionally active umbilical cord blood‐derived basophils expressing FcɛRI, HLA‐DR and CD203cAllergy, 61
G. Trinchieri (2003)
Interleukin-12 and the regulation of innate resistance and adaptive immunityNature Reviews Immunology, 3
K. Takeda, T. Kaisho, S. Akira (2003)
Toll-like receptors.Annual review of immunology, 21
S. Galli (2000)
Mast cells and basophilsCurrent Opinion in Hematology, 7
S. Ben-Sasson, G. Gros, D. Conrad, F. Finkelman, W. Paul (1990)
Cross-linking Fc receptors stimulate splenic non-B, non-T cells to secrete interleukin 4 and other lymphokines.Proceedings of the National Academy of Sciences of the United States of America, 87
H. Karasuyama, K. Mukai, Y. Tsujimura, K. Obata (2009)
Newly discovered roles for basophils: a neglected minority gains new respectNature Reviews Immunology, 9
Alison Macfarlane, O. Kon, Susan Smith, K. Zeibecoglou, L.Nasreen Khan, L. Barata, A. Mceuen, M. Buckley, Andrew Walls, Q. Meng, Marc Humbert, Neil Barnes, Douglas Robinson, S. Ying, A. Kay (2000)
Basophils, eosinophils, and mast cells in atopic and nonatopic asthma and in late-phase allergic reactions in the lung and skin.The Journal of allergy and clinical immunology, 105 1 Pt 1
G. Gauvreau, Jong Lee, R. Watson, Anne-Marie Irani, Lawrence Schwartz, P O'Byrne (2000)
Increased numbers of both airway basophils and mast cells in sputum after allergen inhalation challenge of atopic asthmatics.American journal of respiratory and critical care medicine, 161 5
Basophils act as effector cells in immunoglobulin E–mediated hypersensitivity responses. Artis, Nakanishi and Medzhitov and their colleagues report that basophils present antigen and induce T helper type 2 responses to helminths, allergens and immunoglobulin E immune complexes.
Nature Immunology – Springer Journals
Published: May 24, 2009
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.