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THE HALF-LIFE OF MELATONIN ELIMINATION FROM RAT PLASMA

THE HALF-LIFE OF MELATONIN ELIMINATION FROM RAT PLASMA Tritiated or unlabeled melatonin was infused intra-arterially into unanesthetized male Sprague-Dawley rats. Blood samples were collected from the jugular vein over the next two hours and the melatonin concentrations determined in the plasma by liquid scintillation counting or by RIA. Data from the tritiated melatonin experiments gave a half-life of 23 min, and data from the RIA experiments gave a half-life of 17 min. This content is only available as a PDF. Copyright © 1981 by The Endocrine Society http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Endocrinology Oxford University Press

THE HALF-LIFE OF MELATONIN ELIMINATION FROM RAT PLASMA

GIBBS, FINLEY, P.; VRIEND,, JERRY
Endocrinology , Volume 109 (5) – Nov 1, 1981
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References (11)

Publisher
Oxford University Press
Copyright
Copyright © 1981 by The Endocrine Society
ISSN
0013-7227
eISSN
1945-7170
DOI
10.1210/endo-109-5-1796
Publisher site
See Article on Publisher Site

Abstract

Tritiated or unlabeled melatonin was infused intra-arterially into unanesthetized male Sprague-Dawley rats. Blood samples were collected from the jugular vein over the next two hours and the melatonin concentrations determined in the plasma by liquid scintillation counting or by RIA. Data from the tritiated melatonin experiments gave a half-life of 23 min, and data from the RIA experiments gave a half-life of 17 min. This content is only available as a PDF. Copyright © 1981 by The Endocrine Society

Journal

Endocrinology – Oxford University Press

Published: Nov 1, 1981

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