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Abstract Regulatory T (Treg) cells are a specialized CD4 + T cell subpopulation that are essential for immune homeostasis, immune tolerance, and protection against autoimmunity. There is evidence that sex-steroid hormones estrogen and progesterone modulate Treg cell abundance and phenotype in...
Abstract Preeclampsia is a common pregnancy-specific disorder that is a major cause of both maternal and fetal morbidity and mortality. Central to the pathogenesis of preeclampsia is the production of antiangiogenic and inflammatory factors by the hypoxic placenta, leading to the downstream...
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