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- Publisher
- SPIE
- Copyright
- Copyright © 2005 COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
- ISSN
- 0277-786X
- eISSN
- 1996-756X
- DOI
- 10.1117/12.606832
- Publisher site
- See Article on Publisher Site
Abstract
A microfluidic device, with a temperature control unit to study the behaviour of temperature sensitive hydrogel, has been designed, simulated and fabricated. The system consists of a PDMS (polydimethylsiloxane) microchannel sealed on a Pyrex substrate with microfabricated titanium electrodes for heating and sensing elements. A thermal insulating layer in-between the electrodes and the substrate was found to increase the heat transfer to the fluid and decrease the lateral heat propagation. The temperature profile and the heat distribution in the system were investigated using the commercial software package CFD-ACE+. The device was electrically and thermally characterised. Such a system, biocompatible and re-usable, could be a potential candidate for biomedical applications such as DNA amplification and protein synthesis.
Journal
Proceedings of SPIE – SPIE
Published: Feb 16, 2005