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CHAINSAW : a program for mutating pdb files used as templates in molecular replacement

CHAINSAW : a program for mutating pdb files used as templates in molecular replacement CHAINSAW is a model editing program for use in molecular replacement. Given a sequence alignment between template and target, it modifies the template structure on a residue‐by‐residue basis by pruning nonconserved residues while leaving conserved residues unchanged. Three degrees of pruning are possible. An internal alignment algorithm is used to cope with any residues that may be missing from the X‐ray structure. CHAINSAW has been successfully used as a tool to assist in solving a number of protein structures. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Applied Crystallography Wiley

CHAINSAW : a program for mutating pdb files used as templates in molecular replacement

Journal of Applied Crystallography , Volume 41 (3) – Jun 1, 2008

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References (8)

Publisher
Wiley
Copyright
International Union of Crystallography, 2008
ISSN
1600-5767
eISSN
1600-5767
DOI
10.1107/S0021889808006985
Publisher site
See Article on Publisher Site

Abstract

CHAINSAW is a model editing program for use in molecular replacement. Given a sequence alignment between template and target, it modifies the template structure on a residue‐by‐residue basis by pruning nonconserved residues while leaving conserved residues unchanged. Three degrees of pruning are possible. An internal alignment algorithm is used to cope with any residues that may be missing from the X‐ray structure. CHAINSAW has been successfully used as a tool to assist in solving a number of protein structures.

Journal

Journal of Applied CrystallographyWiley

Published: Jun 1, 2008

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