M. Lesort, W. Chun, G. Johnson, R. Ferrante (1999)
Tissue Transglutaminase Is Increased in Huntington's Disease BrainJournal of Neurochemistry, 73
A. Wyttenbach, Jenny Carmichael, Jina Swartz, Robert Furlong, Yolanda Narain, Julia Rankin, D. Rubinsztein (2000)
Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington's disease.Proceedings of the National Academy of Sciences of the United States of America, 97 6
M. Perutz (1994)
Polar zippers: Their role in human diseaseProtein Science, 3
H. Green (1993)
Human genetic diseases due to codon reiteration: Relationship to an evolutionary mechanismCell, 74
I. Klement, P. Skinner, M. Kaytor, H. Yi, S. Hersch, H. Clark, H. Zoghbi, H. Orr (1998)
Ataxin-1 Nuclear Localization and Aggregation Role in Polyglutamine-Induced Disease in SCA1 Transgenic MiceCell, 95
Moon-Gone Kim, Hong Lee, G. Laforet, Charmian McIntyre, E. Martin, Patrick Chang, Tae-Wan Kim, Marie Williams, P. Reddy, D. Tagle, F. Boyce, L. Won, A. Heller, N. Aronin, M. Difiglia (1999)
Mutant Huntingtin Expression in Clonal Striatal Cells: Dissociation of Inclusion Formation and Neuronal Survival by Caspase InhibitionThe Journal of Neuroscience, 19
L. Morrison, L. Becker, L. Ang, S. Kish (1995)
Polyamines in Human Brain: Regional Distribution and Influence of AgingJournal of Neurochemistry, 65
S. Igarashi, R. Koide, T. Shimohata, M. Yamada, Y. Hayashi, H. Takano, H. Date, M. Oyake, Toshiya Sato, A. Sato, S. Egawa, T. Ikeuchi, Hajime Tanaka, R. Nakano, Keiko Tanaka, I. Hozumi, T. Inuzuka, H. Takahashi, S. Tsuji (1998)
Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretchNature Genetics, 18
Pascal Kahlem, C. Terré, Howard Green, Philippe Djian (1996)
Peptides containing glutamine repeats as substrates for transglutaminase-catalyzed cross-linking: relevance to diseases of the nervous system.Proceedings of the National Academy of Sciences of the United States of America, 93 25
M. Difiglia, E. Sapp, K. Chase, S. Davies, G. Bates, J. Vonsattel, N. Aronin (1997)
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.Science, 277 5334
C. Miller, B. Anderton (1986)
Transglutaminase and the Neuronal Cytoskeleton in Alzheimer's DiseaseJournal of Neurochemistry, 46
C. Huang, P. Faber, F. Persichetti, V. Mittal, J. Vonsattel, M. MacDonald, J. Gusella (1998)
Amyloid Formation by Mutant Huntingtin: Threshold, Progressivity and Recruitment of Normal Polyglutamine ProteinsSomatic Cell and Molecular Genetics, 24
T. Cristofaro, A. Affaitati, L. Cariello, E. Avvedimento, S. Varrone (1999)
The length of polyglutamine tract, its level of expression, the rate of degradation, and the transglutaminase activity influence the formation of intracellular aggregates.Biochemical and biophysical research communications, 260 1
C. Gutekunst, Shihua Li, Hong Yi, James Mulroy, S. Kuemmerle, Randi Jones, David Rye, R. Ferrante, S. Hersch, Xiao-Jiang Li (1999)
Nuclear and Neuropil Aggregates in Huntington’s Disease: Relationship to NeuropathologyThe Journal of Neuroscience, 19
Peter Preis, Hideyuki Saya, Laszlo Nadasdi, Guenther Hochhaus, Victor Levin, Wolfgang Sadée (1988)
Neuronal cell differentiation of human neuroblastoma cells by retinoic acid plus herbimycin A.Cancer research, 48 22
A. Jalava, J. Heikkilä, M. Lintunen, K. Åkerman, S. Påhlman (1992)
Staurosporine induces a neuronal phenotype in SH‐SY5Y human neuroblastoma cells that resembles that induced by the phorbol ester 12‐O‐tetradecanoyl phorbol‐13 acetate TPA)FEBS Letters, 300
Ai Yamamoto, J. Lucas, R. Hen (2000)
Reversal of Neuropathology and Motor Dysfunction in a Conditional Model of Huntington's DiseaseCell, 101
A. Sawa, G. Wiegand, J. Cooper, R. Margolis, A. Sharp, J. Lawler, J. Greenamyre, S. Snyder, C. Ross (1999)
Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarizationNature Medicine, 5
Li (2000)
The early cellular pathology of Huntington's diseaseMol. Neurobiol, 20
Jianwen Zhang, M. Lesort, R. Guttmann, G. Johnson (1998)
Modulation of the in Situ Activity of Tissue Transglutaminase by Calcium and GTP*The Journal of Biological Chemistry, 273
F. Persichetti, F. Trettel, C.Chris Huang, C. Fraefel, H. Timmers, J. Gusella, M. MacDonald (1999)
Mutant Huntingtin Forms in Vivo Complexes with Distinct Context-Dependent Conformations of the Polyglutamine SegmentNeurobiology of Disease, 6
T. Decker, M. Lohmann‐Matthes (1988)
A quick and simple method for the quantitation of lactate dehydrogenase release in measurements of cellular cytotoxicity and tumor necrosis factor (TNF) activity.Journal of immunological methods, 115 1
J. Cooper, G. Schilling, M. Peters, W. Herring, A. Sharp, Z. Kaminsky, J. Masone, F. Khan, M. Delanoy, D. Borchelt, V. Dawson, T. Dawson, C. Ross (1998)
Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture.Human molecular genetics, 7 5
V. Wheeler, Jacqueline White, C. Gutekunst, V. Vrbanac, Meredith Weaver, Xiao-Jiang Li, Shihua Li, Hong Yi, J. Vonsattel, J. Gusella, S. Hersch, W. Auerbach, A. Joyner, M. MacDonald (2000)
Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice.Human molecular genetics, 9 4
Penny Davis, S. Dudek, G. Johnson (1997)
Select Alterations in Protein Kinases and Phosphatases During Apoptosis of Differentiated PC12 CellsJournal of Neurochemistry, 68
Arthur Cooper, K. Sheu, J. Burke, O. Onodera, W. Strittmatter, A. Roses, J. Blass (1997)
Polyglutamine Domains Are Substrates of Tissue Transglutaminase: Does Transglutaminase Play a Role in Expanded CAG/Poly‐Q Neurodegenerative Diseases?Journal of Neurochemistry, 69
(1984)
Transglutaminases. Mol. Cell. Biochem
Chin Lin, S. Tallaksen-Greene, W. Chien, J. Cearley, W. Jackson, A. Crouse, S. Ren, Xiao-Jiang Li, R. Albin, P. Detloff (2001)
Neurological abnormalities in a knock-in mouse model of Huntington's disease.Human molecular genetics, 10 2
Lorand (1984)
TransglutaminasesMol. Cell. Biochem, 58
M. Melan, G. Sluder (1992)
Redistribution and differential extraction of soluble proteins in permeabilized cultured cells. Implications for immunofluorescence microscopy.Journal of cell science, 101 ( Pt 4)
S. Davies, M. Turmaine, Barbara Cozens, M. Difiglia, A. Sharp, C. Ross, E. Scherzinger, E. Wanker, L. Mangiarini, G. Bates (1997)
Formation of Neuronal Intranuclear Inclusions Underlies the Neurological Dysfunction in Mice Transgenic for the HD MutationCell, 90
C. Greenberg, P. Birckbichler, R. Rice (1991)
Transglutaminases: multifunctional cross‐linking enzymes that stabilize tissuesThe FASEB Journal, 5
J. Tucholski, M. Lesort, G. Johnson (2001)
Tissue transglutaminase is essential for neurite outgrowth in human neuroblastoma SH-SY5Y cellsNeuroscience, 102
M. Karpuj, H. Garren, H. Slunt, Donald Price, James Gusella, M. Becher, Lawrence Steinman (1999)
Transglutaminase aggregates huntingtin into nonamyloidogenic polymers, and its enzymatic activity increases in Huntington's disease brain nuclei.Proceedings of the National Academy of Sciences of the United States of America, 96 13
A. Hackam, R. Singaraja, T. Zhang, L. Gan, M. Hayden (1999)
In vitro evidence for both the nucleus and cytoplasm as subcellular sites of pathogenesis in Huntington's disease.Human molecular genetics, 8 1
Arthur Cooper, K. Sheu, J. Burke, W. Strittmatter, V. Gentile, G. Peluso, J. Blass (1999)
Pathogenesis of Inclusion Bodies in (CAG)n/Qn‐Expansion Diseases with Special Reference to the Role of Tissue Transglutaminase and to Selective VulnerabilityJournal of Neurochemistry, 72
A. Hackam, R. Singaraja, C. Wellington, M. Metzler, K. McCutcheon, Taiqi Zhang, M. Kalchman, M. Hayden (1998)
The Influence of Huntingtin Protein Size on Nuclear Localization and Cellular ToxicityThe Journal of Cell Biology, 141
Pascal Kahlem, Howard Green, P. Djian (1998)
Transglutaminase action imitates Huntington's disease: selective polymerization of Huntingtin containing expanded polyglutamine.Molecular cell, 1 4
Kelvin Stott, Jonathan Blackburn, P.J.G. Butler, Max Perutz (1995)
Incorporation of glutamine repeats makes protein oligomerize: implications for neurodegenerative diseases.Proceedings of the National Academy of Sciences of the United States of America, 92 14
D. Appelt, G. Kopen, L. Boyne, B. Balin (1996)
Localization of transglutaminase in hippocampal neurons: implications for Alzheimer's disease.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 44
Gabriele Schilling, M. Becher, A. Sharp, H. Jinnah, Kui Duan, J. Kotzuk, H. Slunt, T. Ratovitski, J. Cooper, N. Jenkins, N. Copeland, D. Price, C. Ross, D. Borchelt (1999)
Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin.Human molecular genetics, 8 3
M. Perutz, Tony Johnson, Masashi Suzuki, J. Finch (1994)
Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases.Proceedings of the National Academy of Sciences of the United States of America, 91 12
A. Lunkes, J. Mandel (1998)
A cellular model that recapitulates major pathogenic steps of Huntington's disease.Human molecular genetics, 7 9
J. Folk (1983)
Mechanism and basis for specificity of transglutaminase-catalyzed epsilon-(gamma-glutamyl) lysine bond formation.Advances in enzymology and related areas of molecular biology, 54
Sven Påhlman, S. Mamaeva, G. Meyerson, Mattsson Me, C. Bjelfman, E. Ortoft, U. Hammerling (1990)
Human neuroblastoma cells in culture: a model for neuronal cell differentiation and function.Acta physiologica Scandinavica. Supplementum, 592
E. Scherzinger, R. Lurz, M. Turmaine, L. Mangiarini, B. Hollenbach, R. Hasenbank, G. Bates, S. Davies, H. Lehrach, E. Wanker (1997)
Huntingtin-Encoded Polyglutamine Expansions Form Amyloid-like Protein Aggregates In Vitro and In VivoCell, 90
F. Saudou, S. Finkbeiner, D. Devys, M. Greenberg (1998)
Huntingtin Acts in the Nucleus to Induce Apoptosis but Death Does Not Correlate with the Formation of Intranuclear InclusionsCell, 95
M. MacDonald, C. Ambrose, M. Duyao, R. Myers, Carol Lin, L. Srinidhi, G. Barnes, Sherryl Taylor, M. James, Nicolet Groot, Heather MacFarlane, B. Jenkins, M. Anderson, N. Wexler, J. Gusella, G. Bates, S. Baxendale, H. Hummerich, S. Kirby, M. North, S. Youngman, R. Mott, G. Zehetner, Z. Sedlacek, A. Poustka, A. Frischauf, H. Lehrach, A. Buckler, D. Church, L. Doucette-Stamm, M. O’Donovan, Laura Riba-Ramírez, Manish Shah, V. Stanton, S. Strobel, K. Draths, Jennifer Wales, P. Dervan, D. Housman, M. Altherr, R. Shiang, L. Thompson, T. Fielder, J. Wasmuth, D. Tagle, J. Valdes, Lon Elmer, M. Allard, L. Castilla, M. Swaroop, K. Blanchard, F. Collins, R. Snell, T. Holloway, Kathleen Gillespie, N. Datson, D. Shaw, P. Harper (1993)
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomesCell, 72
L. Lorand (1998)
DRPLA aggregation and transglutaminase, revisitedNature Genetics, 20
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