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Crook Clinical Chemistry 5 th Floor Tower Guy ' s Hospital London SEI 9 RT England , U
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Crook et al.: Serum total sialic acid and acute phase proteins Eur, J. Clin. Chem. Clin. Biochem. Vol. 32, 1994, pp. 745-747 © 1994 Walter de Gruyter & Co. Berlin · New York By M. A. Crook\ A. Treloar2, M Haq1 and P. Tutt Department ofClinical Chemistry, Guy's Hospital, London, England, U. K. Section of Psychogeriatrics, Division of Psychiatiy, United Medical and Dental Schools, Guy's Hospital London, England, U. K. (Received June 29/July 26, 1994) Summary: Serum total sialic acid has gained recent interest äs a cardiovascular risk factor. We measured serum total sialic acid and three acute phase proteins; C-reactive protein, arantichymotrypsin and <xracid glycoprotein in 37 geriatric patients (age 80.1 ± 7.0 years) and 50 younger subjects (age 40.3 ±11.4 years). Serum total sialic acid was higher in the geriatric subjects 2.41 ± 0.39 mmol/1 versus 2.04 ± 0.35 mmol/1, P < 0.04. Serum {-acid glycoprotein, cti-antichymotrypsin and C-reactive protein were also elevated in the geriatric patients; serum a!-acid glycoprotein being 1.16 ± 0.32 g/l versus 0.41 ± 0.28 g/l, P < 0.0001, serum arantichymotrypsin being 0.80 ± 0.20 g/l versus 0.52 ± 0.10 g/l, P < 0.0001 and serum C-reactive protein being 9.71 ± 21.0
Clinical Chemistry and Laboratory Medicine – de Gruyter
Published: Jan 1, 1994
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