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- Publisher
- Springer Journals
- Copyright
- Copyright © 2010 by Springer-Verlag
- Subject
- Biomedicine; Psychiatry; Pharmacology/Toxicology ; Neurosciences
- ISSN
- 0033-3158
- eISSN
- 1432-2072
- DOI
- 10.1007/s00213-010-1995-4
- pmid
- 20824270
- Publisher site
- See Article on Publisher Site
Abstract
In HIV-positive marijuana smokers, high dronabinol doses safely and effectively increased caloric intake. However, repeated high-dose dronabinol appeared to result in selective tolerance to these effects. These findings indicate that HIV-positive individuals who smoke marijuana may require higher dronabinol doses than are recommended by the FDA. Future research to establish optimal dosing regimens, and reduce the development of tolerance, is required.
Journal
Psychopharmacology – Springer Journals
Published: Dec 1, 2010