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O. Frank
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Zhenwei Lu, R. Mukkamala (2006)
Continuous cardiac output monitoring in humans by invasive and noninvasive peripheral blood pressure waveform analysis.Journal of applied physiology, 101 2
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Continuous blood pressure-derived cardiac output monitoring—should we be thinking long term? Thomas Heldt Laboratory for Electromagnetic and Electronic Systems Massachusetts Institute of Technology Cambridge, Massachusetts e-mail: [email protected] Cardiac output, along with cardiac filling pressure, arterial blood pressure, and heart rate, is one of the most important hemodynamic variables to monitor continuously in patients with compromised cardiovascular performance. This point is illustrated strikingly in Fig. 1 , which shows an example of severe, acute hemorrhage ( 1 ). During blood loss, the commonly monitored systolic arterial blood pressure fell by a nonspecific amount, whereas cardiac output and right atrial pressure dropped precipitously (by 30–40%), providing clear warning of the impending hemodynamic crisis. Similarly, cardiac output and cardiac filling pressure measurements are invaluable for the early diagnosis, monitoring of disease progression, and titration of therapy in heart failure, shock of any type, sepsis, and during cardiac surgery to mention just a few conditions. View larger version (34K): In this window In a new window Fig. 1. Example of severe, acute hemorrhage. [Reprinted from ( 1 ), with permission from Elsevier.] TPR, total peripheral resistance; HR, heart rate; BP, blood pressure; RAP, right atrial pressure; CO, cardiac output; RT, right. Current
Journal of Applied Physiology – The American Physiological Society
Published: Aug 1, 2006
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