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The pharmacology of mTOR inhibition.

The pharmacology of mTOR inhibition. A flurry of reports indicates that we are entering a new phase in the development of mammalian target of rapamycin (mTOR)-based therapies for oncology. Here, we summarize exciting findings regarding mTOR signaling and the outlook for mTOR inhibitors as tools to study the mTOR pathway and as drugs in the clinic. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Science Signaling Pubmed

The pharmacology of mTOR inhibition.

Science Signaling , Volume 2 (67): 1 – Sep 18, 2009

The pharmacology of mTOR inhibition.


Abstract

A flurry of reports indicates that we are entering a new phase in the development of mammalian target of rapamycin (mTOR)-based therapies for oncology. Here, we summarize exciting findings regarding mTOR signaling and the outlook for mTOR inhibitors as tools to study the mTOR pathway and as drugs in the clinic.

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ISSN
1937-9145
eISSN
1937-9145
DOI
10.1126/scisignal.267pe24
pmid
19383975
Publisher site
See Article on Publisher Site

Abstract

A flurry of reports indicates that we are entering a new phase in the development of mammalian target of rapamycin (mTOR)-based therapies for oncology. Here, we summarize exciting findings regarding mTOR signaling and the outlook for mTOR inhibitors as tools to study the mTOR pathway and as drugs in the clinic.

Journal

Science SignalingPubmed

Published: Sep 18, 2009

There are no references for this article.