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- Publisher
- Springer Journals
- Copyright
- Copyright © 2005 by Nature Publishing Group
- Subject
- Life Sciences; Life Sciences, general; Biochemistry, general; Protein Structure; Membrane Biology; Biological Microscopy
- ISSN
- 1545-9993
- eISSN
- 1545-9985
- DOI
- 10.1038/nsmb945
- Publisher site
- See Article on Publisher Site
Abstract
Production of mature mRNAs that encode functional proteins consists of a highly complex pathway of synthesis, processing and export. Along this pathway, the mRNA transcript is scrutinized by quality control machinery at numerous steps. Such extensive RNA surveillance ensures that only correctly processed mature mRNAs are translated and precludes production of aberrant transcripts that could encode mutant or possibly deleterious proteins.
Journal
Nature Structural & Molecular Biology – Springer Journals
Published: Jun 2, 2005