Fan Yuan, Yi Chen, M. Dellian, N. Safabakhsh, N. Ferrara, R. Jain (1996)
Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody.Proceedings of the National Academy of Sciences of the United States of America, 93 25
William Ince, A. Jubb, S. Holden, E. Holmgren, P. Tobin, Meera Sridhar, H. Hurwitz, F. Kabbinavar, W. Novotny, K. Hillan, H. Koeppen (2005)
Association of k-ras, b-raf, and p53 status with the treatment effect of bevacizumab.Journal of the National Cancer Institute, 97 13
C. Willett, Y. Boucher, D. Duda, E. Tomaso, L. Munn, Ricky Tong, S. Kozin, L. Petit, R. Jain, D. Chung, D. Sahani, S. Kalva, K. Cohen, D. Scadden, A. Fischman, Jeffrey Clark, D. Ryan, A. Zhu, L. Blaszkowsky, P. Shellito, M. Mino‐Kenudson, G. Lauwers (2005)
Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 23 31
Manuel Macedo (1983)
Theory and Application
S. Grossman, J. Batara (2004)
Current management of glioblastoma multiforme.Seminars in oncology, 31 5
C. Willett, Y. Boucher, E. Tomaso, D. Duda, L. Munn, Ricky Tong, D. Chung, D. Sahani, S. Kalva, S. Kozin, M. Mino, K. Cohen, D. Scadden, A. Hartford, A. Fischman, Jeffrey Clark, D. Ryan, A. Zhu, L. Blaszkowsky, Helen Chen, P. Shellito, G. Lauwers, R. Jain (2004)
Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancerNature Medicine, 10
(1973)
Nonparametrical Statistical Inference
Réginald Ansiaux, C. Baudelet, B. Jordan, N. Beghein, P. Sonveaux, J. Wever, P. Martinive, V. Grégoire, O. Féron, B. Gallez (2005)
Thalidomide radiosensitizes tumors through early changes in the tumor microenvironment.Clinical cancer research : an official journal of the American Association for Cancer Research, 11 2 Pt 1
Ricky Tong, Y. Boucher, S. Kozin, F. Winkler, D. Hicklin, R. Jain (2004)
Vascular Normalization by Vascular Endothelial Growth Factor Receptor 2 Blockade Induces a Pressure Gradient Across the Vasculature and Improves Drug Penetration in TumorsCancer Research, 64
D. Senger, Galli Sj, A. Dvorak, C. Perruzzi, Harvey Vs, H. Dvorak (1983)
Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid.Science, 219 4587
Arabinda Das, N. Banik, Sunil Patel, S. Ray (2004)
Dexamethasone protected human glioblastoma U87MG cells from temozolomide induced apoptosis by maintaining Bax:Bcl-2 ratio and preventing proteolytic activitiesMolecular Cancer, 3
B. Stoll, Cristiano Migliorini, A. Kadambi, L. Munn, R. Jain (2003)
A mathematical model of the contribution of endothelial progenitor cells to angiogenesis in tumors: implications for antiangiogenic therapy.Blood, 102 7
O. Casanovas, D. Hicklin, G. Bergers, D. Hanahan (2005)
Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors.Cancer cell, 8 4
Don Gilden, Maria Nagel (2006)
MRI in patients with high-grade gliomas treated with bevacizumab and chemotherapyNeurology, 67
S. Weis, D. Cheresh (2005)
Pathophysiological consequences of VEGF-induced vascular permeabilityNature, 437
R. Jain, D. Duda, Jeffrey Clark, J. Loeffler (2006)
Lessons from phase III clinical trials on anti-VEGF therapy for cancerNature Clinical Practice Oncology, 3
M. Lichy, B. Wietek, J. Mugler, W. Horger, M. Menzel, A. Anastasiadis, K. Siegmann, T. Niemeyer, Arnulf Königsrainer, B. Kiefer, F. Schick, C. Claussen, H. Schlemmer (2005)
Magnetic Resonance Imaging of the Body Trunk Using a Single-Slab, 3-Dimensional, T2-weighted Turbo-Spin-Echo Sequence With High Sampling Efficiency (SPACE) for High Spatial Resolution Imaging: Initial Clinical ExperiencesInvestigative Radiology, 40
A. Kouwe, T. Benner, B. Fischl, F. Schmitt, D. Salat, M. Harder, A. Sorensen, A. Dale (2005)
On-line automatic slice positioning for brain MR imagingNeuroImage, 27
P. Tofts, G. Brix, D. Buckley, J. Evelhoch, E. Henderson, M. Knopp, H. Larsson, Ting-Yim Lee, N. Mayr, G. Parker, R. Port, June Taylor, R. Weisskoff (1999)
Estimating kinetic parameters from dynamic contrast‐enhanced t1‐weighted MRI of a diffusable tracer: Standardized quantities and symbolsJournal of Magnetic Resonance Imaging, 10
A. Pathak, K. Schmainda, B. Ward, J. Linderman, Kelly Rebro, A. Greene (2001)
MR‐derived cerebral blood volume maps: Issues regarding histological validation and assessment of tumor angiogenesisMagnetic Resonance in Medicine, 46
H. Dvorak (2002)
Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 20 21
M. Law, S. Cha, E. Knopp, G. Johnson, J. Arnett, A. Litt (2002)
High-grade gliomas and solitary metastases: differentiation by using perfusion and proton spectroscopic MR imaging.Radiology, 222 3
C. Brown, N. Khodarev, Jianqing Yu, T. Moo-Young, E. Labay, T. Darga, M. Posner, R. Weichselbaum, H. Mauceri (2004)
Glioblastoma cells block radiation‐induced programmed cell death of endothelial cellsFEBS Letters, 565
J. Dennie, J. Mandeville, J. Boxerman, Scott Packard, B. Rosen, R. Weisskoff (1998)
NMR imaging of changes in vascular morphology due to tumor angiogenesisMagnetic Resonance in Medicine, 40
Hitoshi Yoshiji, S. Harris, U. Thorgeirsson (1997)
Vascular endothelial growth factor is essential for initial but not continued in vivo growth of human breast carcinoma cells.Cancer research, 57 18
J. Boxerman, K. Schmainda, R. Weisskoff (2006)
Relative cerebral blood volume maps corrected for contrast agent extravasation significantly correlate with glioma tumor grade, whereas uncorrected maps do not.AJNR. American journal of neuroradiology, 27 4
F. Winkler, S. Kozin, Ricky Tong, Sung-suk Chae, M. Booth, I. Garkavtsev, Lei Xu, D. Hicklin, D. Fukumura, E. Tomaso, L. Munn, R. Jain (2004)
Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases.Cancer cell, 6 6
A. Jackson, G. Jayson, K. Li, X. Zhu, D. Checkley, J. Tessier, J. Waterton (2003)
Reproducibility of quantitative dynamic contrast-enhanced MRI in newly presenting glioma.The British journal of radiology, 76 903
R. Jain (2001)
Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapyNature Medicine, 7
I. Tremont-Lukats, M. Gilbert (2003)
Advances in molecular therapies in patients with brain tumors.Cancer control : journal of the Moffitt Cancer Center, 10 2
K. Schmainda, S. Rand, A. Joseph, R. Lund, B. Ward, A. Pathak, J. Ulmer, M. Badruddoja, H. Krouwer (2004)
Characterization of a first-pass gradient-echo spin-echo method to predict brain tumor grade and angiogenesis.AJNR. American journal of neuroradiology, 25 9
J. Segers, V. Fazio, Réginald Ansiaux, P. Martinive, O. Féron, P. Wallemacq, B. Gallez (2006)
Potentiation of cyclophosphamide chemotherapy using the anti-angiogenic drug thalidomide: importance of optimal scheduling to exploit the 'normalization' window of the tumor vasculature.Cancer letters, 244 1
A. Sorensen, Shveta Patel, C. Harmath, Sarah Bridges, Jennifer Synnott, Amy Sievers, Young-Ho Yoon, E. Lee, Michael Yang, Robert Lewis, G. Harris, M. Lev, P. Schaefer, B. Buchbinder, G. Barest, Kei Yamada, J. Ponzo, H. Kwon, J. Gemmete, J. Farkas, A. Tievsky, Richard Ziegler, Megan Salhus, R. Weisskoff (2001)
Comparison of diameter and perimeter methods for tumor volume calculation.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 19 2
F. Bertolini, Y. Shaked, P. Mancuso, R. Kerbel (2006)
The multifaceted circulating endothelial cell in cancer: towards marker and target identificationNature Reviews Cancer, 6
D. Duda, K. Cohen, E. Tomaso, P. Au, Rachael Klein, D. Scadden, C. Willett, R. Jain (2006)
Differential CD146 expression on circulating versus tissue endothelial cells in rectal cancer patients: implications for circulating endothelial and progenitor cells as biomarkers for antiangiogenic therapy.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 24 9
S. Rafii, D. Lyden, R. Benezra, K. Hattori, B. Heissig (2002)
Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy?Nature Reviews Cancer, 2
M. Chamberlain, M. Glantz, L. Chalmers, A. Horn, A. Sloan (2006)
Early necrosis following concurrent temozolomide and radiotherapy in adult patients with glioblastoma.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 24 18_suppl
Joonmi Oh, S. Cha, Ashley Aiken, E. Han, J. Crane, J. Stainsby, G. Wright, W. Dillon, S. Nelson (2005)
Quantitative apparent diffusion coefficients and T2 relaxation times in characterizing contrast enhancing brain tumors and regions of peritumoral edemaJournal of Magnetic Resonance Imaging, 21
Rakesh Jain, N. Safabakhsh, Axel Sckell, Yi Chen, Ping Jiang, Laura Benjamin, Fan Yuan, Eli Keshet (1998)
Endothelial cell death, angiogenesis, and microvascular function after castration in an androgen-dependent tumor: role of vascular endothelial growth factor.Proceedings of the National Academy of Sciences of the United States of America, 95 18
Eric Wong, K. Hess, M. Gleason, K. Jaeckle, A. Kyritsis, M. Prados, V. Levin, W. Yung (1999)
Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 17 8
R. Jain (2005)
Normalization of Tumor Vasculature: An Emerging Concept in Antiangiogenic TherapyScience, 307
R. Motzer, M. Michaelson, B. Redman, G. Hudes, G. Wilding, R. Figlin, M. Ginsberg, Sindy Kim, C. Baum, S. Deprimo, Jim Li, C. Bello, C. Theuer, D. George, B. Rini (2006)
Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 24 1
F. Dignat-George, F. Sabatier, A. Blann, A. Woywodt (2007)
Detection of circulating endothelial cells: CD146-based magnetic separation enrichment or flow cytometric assay?Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 25 5
(2004)
Mixed Effects Models. Theory and Application (New York: John Wiley & Sons)
Elena Fomchenko, E. Holland (2006)
Origins of brain tumors—a disease of stem cells?Nature Clinical Practice Neurology, 2
D. Reardon, J. Quinn, J. Rich, A. Desjardins, J. Vredenburgh, S. Gururangan, S. Sathornsumetee, M. Badruddoja, R. McLendon, J. Provenzale, J. Herndon, J. Dowell, Jill Burkart, H. Newton, A. Friedman, H. Friedman (2005)
Phase I trial of irinotecan plus temozolomide in adults with recurrent malignant gliomaCancer, 104
M. Aghi, K. Cohen, Rachael Klein, D. Scadden, E. Chiocca (2006)
Tumor stromal-derived factor-1 recruits vascular progenitors to mitotic neovasculature, where microenvironment influences their differentiated phenotypes.Cancer research, 66 18
A. Kadambi, C. Carreira, C. Yun, T. Padera, D. Dolmans, P. Carmeliet, D. Fukumura, R. Jain (2001)
Vascular endothelial growth factor (VEGF)-C differentially affects tumor vascular function and leukocyte recruitment: role of VEGF-receptor 2 and host VEGF-A.Cancer research, 61 6
L. Østergaard, A. Sorensen, K. Kwong, R. Weisskoff, C. Gyldensted, B. Rosen (1996)
High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part II: Experimental comparison and preliminary resultsMagnetic Resonance in Medicine, 36
A. Jubb, H. Hurwitz, W. Bai, E. Holmgren, P. Tobin, A. Guerrero, F. Kabbinavar, S. Holden, W. Novotny, G. Frantz, K. Hillan, H. Koeppen (2006)
Impact of vascular endothelial growth factor-A expression, thrombospondin-2 expression, and microvessel density on the treatment effect of bevacizumab in metastatic colorectal cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 24 2
T. Benner, J. Wisco, A. Kouwe, B. Fischl, M. Vangel, Fred Hochberg, A. Sorensen (2006)
Comparison of manual and automatic section positioning of brain MR images.Radiology, 239 1
S. Rempel, S. Dudas, S. Ge, J. Gutierrez (2000)
Identification and localization of the cytokine SDF1 and its receptor, CXC chemokine receptor 4, to regions of necrosis and angiogenesis in human glioblastoma.Clinical cancer research : an official journal of the American Association for Cancer Research, 6 1
M. Prados, K. Lamborn, W. Yung, K. Jaeckle, H. Robins, M. Mehta, H. Fine, P. Wen, T. Cloughesy, Susan Chang, M. Nicholas, D. Schiff, H. Greenberg, L. Junck, K. Fink, K. Hess, J. Kuhn (2006)
A phase 2 trial of irinotecan (CPT-11) in patients with recurrent malignant glioma: a North American Brain Tumor Consortium study.Neuro-oncology, 8 2
S. Wedge, J. Kendrew, L. Hennequin, P. Valentine, S. Barry, S. Brave, N. Smith, N. James, M. Dukes, J. Curwen, R. Chester, J. Jackson, S. Boffey, Lyndsey Kilburn, S. Barnett, Graham Richmond, P. Wadsworth, Mike Walker, Alison Bigley, S. Taylor, L. Cooper, Sarah Beck, J. Jürgensmeier, D. Ogilvie (2005)
AZD2171: a highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer.Cancer research, 65 10
P. Carmeliet (2005)
Angiogenesis in life, disease and medicineNature, 438
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