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Extended in vitro maturation of immature oocytes from stimulated cycles: an analysis of fertilization potential, embryo development, and reproductive outcomes

Extended in vitro maturation of immature oocytes from stimulated cycles: an analysis of... J Assist Reprod Genet (2010) 27:347–356 DOI 10.1007/s10815-010-9416-5 ASSISTED REPRODUCTION Extended in vitro maturation of immature oocytes from stimulated cycles: an analysis of fertilization potential, embryo development, and reproductive outcomes David E. Reichman & Joseph Politch & Elizabeth S. Ginsburg & Catherine Racowsky Received: 20 January 2010 /Accepted: 6 April 2010 /Published online: 28 April 2010 Springer Science+Business Media, LLC 2010 Abstract Conclusion Efficacy of 24 h IVM for cumulus-stripped GV Purpose To investigate 24 h in vitro maturation (IVM) of and MI oocytes for either clinical use or study of normal cumulus-stripped immature oocytes from stimulated cycles. meiotic maturation is questionable. Methods 263 oocytes identified as immature after cumulus . . . stripping for ICSI were subjected to in vitro maturation Keywords ICSI Immature oocytes In-vitro maturation (IVM). Fertilization rates and reproductive outcomes of Ovarian stimulation matured oocytes were compared against 234 in vivo matured sibling oocytes (IVO-MII-Sib) from the same cycles (n=41). Day 2 embryo development was compared Introduction against 116 embryos from ICSI cycles having no IVM (IVO-Ext controls). Following ovarian stimulation, oocytes are retrieved at Results While fertilization rates were similar between IVM varying stages of meiotic maturity, with an overall average and IVO-MII-Sib oocytes http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Assisted Reproduction and Genetics Springer Journals

Extended in vitro maturation of immature oocytes from stimulated cycles: an analysis of fertilization potential, embryo development, and reproductive outcomes

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References (39)

Publisher
Springer Journals
Copyright
Copyright © 2010 by Springer Science+Business Media, LLC
Subject
Medicine & Public Health; Human Genetics ; Developmental Biology; Gynecology
ISSN
1058-0468
eISSN
1573-7330
DOI
10.1007/s10815-010-9416-5
pmid
20425141
Publisher site
See Article on Publisher Site

Abstract

J Assist Reprod Genet (2010) 27:347–356 DOI 10.1007/s10815-010-9416-5 ASSISTED REPRODUCTION Extended in vitro maturation of immature oocytes from stimulated cycles: an analysis of fertilization potential, embryo development, and reproductive outcomes David E. Reichman & Joseph Politch & Elizabeth S. Ginsburg & Catherine Racowsky Received: 20 January 2010 /Accepted: 6 April 2010 /Published online: 28 April 2010 Springer Science+Business Media, LLC 2010 Abstract Conclusion Efficacy of 24 h IVM for cumulus-stripped GV Purpose To investigate 24 h in vitro maturation (IVM) of and MI oocytes for either clinical use or study of normal cumulus-stripped immature oocytes from stimulated cycles. meiotic maturation is questionable. Methods 263 oocytes identified as immature after cumulus . . . stripping for ICSI were subjected to in vitro maturation Keywords ICSI Immature oocytes In-vitro maturation (IVM). Fertilization rates and reproductive outcomes of Ovarian stimulation matured oocytes were compared against 234 in vivo matured sibling oocytes (IVO-MII-Sib) from the same cycles (n=41). Day 2 embryo development was compared Introduction against 116 embryos from ICSI cycles having no IVM (IVO-Ext controls). Following ovarian stimulation, oocytes are retrieved at Results While fertilization rates were similar between IVM varying stages of meiotic maturity, with an overall average and IVO-MII-Sib oocytes

Journal

Journal of Assisted Reproduction and GeneticsSpringer Journals

Published: Apr 28, 2010

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