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Ann. clin. Biochem. 12 (1975) 33 TECHNICAL BULLETIN No. 34 Prepared for the Scientific and Technical Committee of the AssDciation of Clinical Biochemists LINDA SLATER, P. M. CARTER, AND J. R. HOBBS Department of Chemical Pathology, Westminster Hospital and Medical School, 17 Page Street, London SWIP 2AR Albumin is the serum protein most often measured tionate serum proteins was introduced by Howe in clinical chemistry. Estimations of serum levels (1921 and 1923) to replace ammonium sulphate can be of value in patients with various protein (Hammarsten, 1873; Pinkus, 1901-1902), and has losing states, cirrhosis, and myelomatosis. This the advantage that it does not need to be removed bulletin comprises an evaluation and comparison prior to estimation of total protein by nitrogen analysis. Later, Campbell and Hanna (1937) of methods. Many methods are available for the determination suggested the use of sodium sulphite which they of albumin levels in body fluids, depending on a wide thought had a number of advantages over the variety of the physical and chemical properties of sulphate salt and required less time for globulin albumin. Although it is in patients with the diseases precipitation. In practical terms sodium sulphite is already mentioned that accurate albumin
Annals of Clinical Biochemistry: An International Journal of Biochemistry and Laboratory Medicine – SAGE
Published: Jan 1, 1975
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