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New approaches to population stratification in genome-wide association studies

New approaches to population stratification in genome-wide association studies This article compares the different approaches that have been developed for detecting confounding due to population stratification, family structure and cryptic relatedness, with an emphasis on the potential of mixed models for addressing these problems simultaneously. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nature Reviews Genetics Springer Journals

New approaches to population stratification in genome-wide association studies

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References (47)

Publisher
Springer Journals
Copyright
Copyright © 2010 by Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.
Subject
Biomedicine; Biomedicine, general; Human Genetics; Cancer Research; Agriculture; Gene Function; Animal Genetics and Genomics
ISSN
1471-0056
eISSN
1471-0064
DOI
10.1038/nrg2813
Publisher site
See Article on Publisher Site

Abstract

This article compares the different approaches that have been developed for detecting confounding due to population stratification, family structure and cryptic relatedness, with an emphasis on the potential of mixed models for addressing these problems simultaneously.

Journal

Nature Reviews GeneticsSpringer Journals

Published: Jun 15, 2010

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