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SUBACUTE SCLEROSING PANENCEPHALITIS WITH SPECIAL REFERENCE TO THE ULTRASTRUCTURE OF INCLUSIONS IN THE BRAIN AND LUNG

SUBACUTE SCLEROSING PANENCEPHALITIS WITH SPECIAL REFERENCE TO THE ULTRASTRUCTURE OF INCLUSIONS IN... A 7‐year‐old boy, who was diagnosed as typical SSPE by clinical data and laboratory findings, was autopsied and observed by immunofluorescent techniques, light and electron microscope. The morphological characteristics in the brain were perivascular cuffings with plasma cells, lymphocytes and mononuclear cells, gliosis and a large number of intranuclear and intracytoplasmk inclusions in the neuroglias and nerve cells. Various kinds of intranuclear inclusions were elucidated by electron microscopy and the fine structures of these inclusions were described in detail. At least five types of intranuclear inclusions were regarded as specific in SSPE. The presence of intranuclear inclusions of mononuclear cells in the lungs resembling the inclusions in the neuroglias suggested that the disease was not localized in the brain but could be disseminated throughout the body. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Pathology International Wiley

SUBACUTE SCLEROSING PANENCEPHALITIS WITH SPECIAL REFERENCE TO THE ULTRASTRUCTURE OF INCLUSIONS IN THE BRAIN AND LUNG

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References (36)

Publisher
Wiley
Copyright
Copyright © 1978 Wiley Subscription Services, Inc., A Wiley Company
ISSN
1320-5463
eISSN
1440-1827
DOI
10.1111/j.1440-1827.1978.tb01255.x
Publisher site
See Article on Publisher Site

Abstract

A 7‐year‐old boy, who was diagnosed as typical SSPE by clinical data and laboratory findings, was autopsied and observed by immunofluorescent techniques, light and electron microscope. The morphological characteristics in the brain were perivascular cuffings with plasma cells, lymphocytes and mononuclear cells, gliosis and a large number of intranuclear and intracytoplasmk inclusions in the neuroglias and nerve cells. Various kinds of intranuclear inclusions were elucidated by electron microscopy and the fine structures of these inclusions were described in detail. At least five types of intranuclear inclusions were regarded as specific in SSPE. The presence of intranuclear inclusions of mononuclear cells in the lungs resembling the inclusions in the neuroglias suggested that the disease was not localized in the brain but could be disseminated throughout the body.

Journal

Pathology International – Wiley

Published: Jan 1, 1978

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