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- Publisher
- Oxford University Press
- Copyright
- © Published by Oxford University Press.
- Subject
- DEBATE-CONTINUED
- ISSN
- 0268-1161
- eISSN
- 1460-2350
- DOI
- 10.1093/humrep/den376
- pmid
- 18948310
- Publisher site
- See Article on Publisher Site
Abstract
The recent debate on preimplantation genetic screening (PGS) has raised questions about its routine use in clinical practice. It has been suggested that the most effective way to resolve the debate about the usefulness of PGS is to perform more well-designed and well-executed randomized controlled trials (RCTs). However, in view of the lack of evidence for the effectiveness of PGS and the accumulating evidence for its harmfulness, it is our opinion that it is unethical to perform additional RCTs for the indication advanced maternal age using cleavage stage biopsy.
Journal
Human Reproduction – Oxford University Press
Published: Dec 23, 2008
Keywords: Keywords PGS ethics clinical practice