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Letter to the Editor From Virú-Loza and Chávez-Nomberto: “Safety and Efficacy of Pediatric Growth Hormone Therapy: Results From the Full KIGS Cohort”

Letter to the Editor From Virú-Loza and Chávez-Nomberto: “Safety and Efficacy of Pediatric Growth... The Journal of Clinical Endocrinology & Metabolism, 2023, 108, e354–e355 https://doi.org/10.1210/clinem/dgad054 Advance access publication 31 January 2023 Letter to the Editor Letter to the Editor From Virú-Loza and Chávez-Nomberto: “Safety and Efficacy of Pediatric Growth Hormone Therapy: Results From the Full KIGS Cohort” 1 2 Manuel André Virú-Loza and Ruth Elizabeth Chávez-Nomberto Department of Pediatrics, Hospital Nacional Dos de Mayo, Lima, Peru Postgraduate School, Universidad Nacional Federico Villarreal, Lima, Peru Correspondence: Manuel André Virú-Loza, MD, MSc, Department of Pediatrics, Hospital Nacional Dos de Mayo, 2790 Brasil Ave, Pueblo Libre, Lima, Peru. Email: [email protected]. Key Words: human growth hormone, dwarfism, bone neoplasms, urinary bladder neoplasms, lymphoma, child Abbreviations: AE, adverse effect; GeNeSIS, Genetics and Neuroendocrinology of Short Stature International Study; KIGS, Kabi/Pfizer International Growth Database; rhGH, recombinant human growth hormone; SAE, serious adverse effect; SIR, standardized incidence ratio. We read with great interest the study by Maghnie et al (1) Hormone Treatments in Europe (SAGhE) study showed a sig- about the safety and efficacy of recombinant human growth nificantly increased risk of bone (SIR 5.2; 95% CI, 2.7-10.1) hormone (rhGH) in children from the full Kabi/Pfizer and bladder (SIR 14.0; 95% CI, 4.5-43.4) cancer in patients International Growth Database (KIGS) http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The Journal of Clinical Endocrinology & Metabolism Oxford University Press

Letter to the Editor From Virú-Loza and Chávez-Nomberto: “Safety and Efficacy of Pediatric Growth Hormone Therapy: Results From the Full KIGS Cohort”

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References (5)

Publisher
Oxford University Press
Copyright
© The Author(s) 2023. Published by Oxford University Press on behalf of the Endocrine Society. All rights reserved. For permissions, please e-mail: [email protected]
ISSN
0021-972X
eISSN
1945-7197
DOI
10.1210/clinem/dgad054
Publisher site
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Abstract

The Journal of Clinical Endocrinology & Metabolism, 2023, 108, e354–e355 https://doi.org/10.1210/clinem/dgad054 Advance access publication 31 January 2023 Letter to the Editor Letter to the Editor From Virú-Loza and Chávez-Nomberto: “Safety and Efficacy of Pediatric Growth Hormone Therapy: Results From the Full KIGS Cohort” 1 2 Manuel André Virú-Loza and Ruth Elizabeth Chávez-Nomberto Department of Pediatrics, Hospital Nacional Dos de Mayo, Lima, Peru Postgraduate School, Universidad Nacional Federico Villarreal, Lima, Peru Correspondence: Manuel André Virú-Loza, MD, MSc, Department of Pediatrics, Hospital Nacional Dos de Mayo, 2790 Brasil Ave, Pueblo Libre, Lima, Peru. Email: [email protected]. Key Words: human growth hormone, dwarfism, bone neoplasms, urinary bladder neoplasms, lymphoma, child Abbreviations: AE, adverse effect; GeNeSIS, Genetics and Neuroendocrinology of Short Stature International Study; KIGS, Kabi/Pfizer International Growth Database; rhGH, recombinant human growth hormone; SAE, serious adverse effect; SIR, standardized incidence ratio. We read with great interest the study by Maghnie et al (1) Hormone Treatments in Europe (SAGhE) study showed a sig- about the safety and efficacy of recombinant human growth nificantly increased risk of bone (SIR 5.2; 95% CI, 2.7-10.1) hormone (rhGH) in children from the full Kabi/Pfizer and bladder (SIR 14.0; 95% CI, 4.5-43.4) cancer in patients International Growth Database (KIGS)

Journal

The Journal of Clinical Endocrinology & Metabolism – Oxford University Press

Published: Jan 31, 2023

Keywords: human growth hormone; dwarfism; bone neoplasms; urinary bladder neoplasms; lymphoma; child

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