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More on Interferon-Induced Cutaneous Necrosis

More on Interferon-Induced Cutaneous Necrosis To the Editor: Sheremata et al. (June 8 issue)1 reported severe necrotizing cutaneous lesions complicating treatment with interferon beta-1b in a patient with multiple sclerosis. They indicated that it was a new complication of treatment with interferon beta-1b, which had not been observed with natural or recombinant interferon alfa. However, we described a case of cutaneous necrosis caused by the injection of interferon alfa in a patient with chronic myelogenous leukemia.2 Cutaneous necrosis due to interferon alfa was also reported by Cnudde et al.3 and subsequently by Orlow and Friedman-Kien4 in patients with Kaposi's sarcoma related to the acquired immunodeficiency . . . http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The New England Journal of Medicine The New England Journal of Medicine

More on Interferon-Induced Cutaneous Necrosis

The New England Journal of Medicine , Volume 333 (18): 3 – Nov 2, 1995

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References (4)

Publisher
The New England Journal of Medicine
Copyright
Copyright © 1995 Massachusetts Medical Society. All rights reserved.
ISSN
0028-4793
eISSN
1533-4406
DOI
10.1056/NEJM199511023331815
pmid
7565991
Publisher site
See Article on Publisher Site

Abstract

To the Editor: Sheremata et al. (June 8 issue)1 reported severe necrotizing cutaneous lesions complicating treatment with interferon beta-1b in a patient with multiple sclerosis. They indicated that it was a new complication of treatment with interferon beta-1b, which had not been observed with natural or recombinant interferon alfa. However, we described a case of cutaneous necrosis caused by the injection of interferon alfa in a patient with chronic myelogenous leukemia.2 Cutaneous necrosis due to interferon alfa was also reported by Cnudde et al.3 and subsequently by Orlow and Friedman-Kien4 in patients with Kaposi's sarcoma related to the acquired immunodeficiency . . .

Journal

The New England Journal of MedicineThe New England Journal of Medicine

Published: Nov 2, 1995

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