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Rizzo Aa, Mergenhagen Se (1965)
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cutaneous injections of 0.2 cc of the antigen solution Allergic Periodontal Disease into the shaved flexor surfaces of each limb and in the nuchal area. This provided a total dose of 5 mg of in Sensitized Squirrel Monkeys* ovalbumin. One and two weeks thereafter 5 mg was administered in a single 0.2 cc injection beneath the skin of the back; and each week for the next three by weeks 1 mg was given in the same manner. Booster R i c h a r d R . R a n n e y , d .d .s ., m .s . doses of 1 mg were given if more than six weeks elapsed H e l m u t A. Z a n d e r , d .d .s ., m .s . between the last injection and initiation of gingival challenge. Four of the monkeys were not sensitized. The H y p e r s e n s i t i v i t y r e a c t i o n s have been suggested as remaining two monkeys were used for passive transfer a possible mechanism for the mediation of tissue injury experimentation, receiving
Journal of Periodontology – Wiley
Published: Jan 1, 1970
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