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BREAST Capsular Contractures: A Systematic Review Antonino Araco, M.D. Background: The aim of this article was to review the current literature on Riccardo Caruso, M.D. capsular contractures, focusing in particular on the epidemiology, risk factors, Francesco Araco, M.D. cause, and treatment modalities, to provide the plastic surgeon with an up-to- John Overton date review of the current available evidence. Gianpiero Gravante, M.D. Methods: A literature search was undertaken of the MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials databases. The search strategy Bromsgrove, London, and Leicester, United Kingdom; and Rome, Italy was conducted using three groups of key words, with the first relating to the organ involved (breast), the second relating to the surgical procedure per- formed and related technical issues, and the third relating to the surgical complications. Potentially relevant articles were identified by means of the title and the abstract, and full articles were obtained and assessed in detail. Results: Only a few studies have included large enough sample sizes, were conducted in a prospective manner, were adequately randomized, and achieved adequate follow-up periods to obtain a true measure of rates of capsular con- traction occurrence. Recent advances in molecular biology, microbiology, im- munology, and basic
Plastic & Reconstructive Surgery – Wolters Kluwer Health
Published: Dec 1, 2009
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