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MOSAIC ORGANIZATION AND EXPRESSION OF THE MITOCHONDRIAL DNA REGION CONTROLLING CYTOCHROME c REDUCTASE AND OXIDASE: III - A MODEL OF STRUCTURE AND FUNCTION
- Publisher
- Springer Journals
- Copyright
- Copyright © 1981 by Springer-Verlag
- Subject
- Life Sciences; Microbial Genetics and Genomics; Microbiology; Biochemistry, general; Cell Biology; Plant Sciences; Proteomics
- ISSN
- 0172-8083
- eISSN
- 1432-0983
- DOI
- 10.1007/BF00419582
- Publisher site
- See Article on Publisher Site
Abstract
A physical map of the COB region in mtDNA of yeast has been established. This region harbours a split gene coding for apocytochrome b. It includes restriction sites of seven endonucleases (EcoRI, HindII, HindIII, HaeIII, HpaII, AluI and BamHI). Various mtDNA sequences of this region, retained in a series of genetically characterized rho− clones have been allocated to this map. The combination of this physical map with a genetic map of the rho− clones revealed that 1) cob− mutational sites spread over 8,400 bp, 2) mutations in sequences coding for apocytochrome b map in five distinct segments which are separated by intervening sequences with minimum lengths from 350 to 1,900 bp.
Journal
Current Genetics – Springer Journals
Published: Sep 21, 2004