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Response on the author's reply to the Letter to the Editor: Contradictory data on type 1 diabetes in a recently published article ‘Risks of neurological and immune‐related diseases, including narcolepsy, after vaccination with Pandemrix’

Response on the author's reply to the Letter to the Editor: Contradictory data on type 1 diabetes... Dear Sir, Type 1 diabetes and vaccinations has been a subject for investigations without clear conclusions. The increase in the frequency of type 1 diabetes in recent years has been paralleled by an increase in vaccination frequency. It is therefore of outmost importance that conclusions regarding this association are based on clear and reproducible results. For reader information, the number of type 1 diabetes cases in the unvaccinated groups (0–9 years: 153 cases; 10–19 years: 183 cases) was chosen by the authors not be presented in the published article but are those figures obtained in the study and used for the calculations of hazard ratios according to the same persons. The authors answered in general terms, but their arguments did not explain the significant discrepancy in the critical age group 10–19 years. Using their cut‐off limits for age groups about 11% is still not reported (62 cases in the study) when compared with the SWEDIABKIDS registry. The authors give new information, not clearly presented in the article. The spans of age at diagnosis were in fact 0–12 and 10–22 years, respectively, although the groups were named 0–9 and 10–19 years. They explain the estimated contradictory data with this http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Internal Medicine Wiley

Response on the author's reply to the Letter to the Editor: Contradictory data on type 1 diabetes in a recently published article ‘Risks of neurological and immune‐related diseases, including narcolepsy, after vaccination with Pandemrix’

Andersson, L.
Journal of Internal Medicine , Volume 277 (2) – Feb 1, 2015
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Publisher
Wiley
Copyright
Copyright © 2015 The Association for the Publication of the Journal of Internal Medicine
ISSN
0954-6820
eISSN
1365-2796
DOI
10.1111/joim.12327
pmid
25359510
Publisher site
See Article on Publisher Site

Abstract

Dear Sir, Type 1 diabetes and vaccinations has been a subject for investigations without clear conclusions. The increase in the frequency of type 1 diabetes in recent years has been paralleled by an increase in vaccination frequency. It is therefore of outmost importance that conclusions regarding this association are based on clear and reproducible results. For reader information, the number of type 1 diabetes cases in the unvaccinated groups (0–9 years: 153 cases; 10–19 years: 183 cases) was chosen by the authors not be presented in the published article but are those figures obtained in the study and used for the calculations of hazard ratios according to the same persons. The authors answered in general terms, but their arguments did not explain the significant discrepancy in the critical age group 10–19 years. Using their cut‐off limits for age groups about 11% is still not reported (62 cases in the study) when compared with the SWEDIABKIDS registry. The authors give new information, not clearly presented in the article. The spans of age at diagnosis were in fact 0–12 and 10–22 years, respectively, although the groups were named 0–9 and 10–19 years. They explain the estimated contradictory data with this

Journal

Journal of Internal Medicine – Wiley

Published: Feb 1, 2015

There are no references for this article.