Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 7-Day Trial for You or Your Team.

Learn More →

Differences in the uptake of modified low density lipoproteins by tissue cultured endothelial cells.

Differences in the uptake of modified low density lipoproteins by tissue cultured endothelial cells. Acetylated low density lipoprotein (Ac-LDL) is taken up by bovine aortic and adrenal capillary cells but not by brain capillary cells. This indicates that the uptake of Ac-LDL is not a feature of all types of endothelial cell. A quantitative examination of lipoprotein uptake by flow cytometry showed cells in G2M took up 45% more Ac-LDL than those in G1S. Compared with confluent cultures, sub-confluent bovine aortic cells took up three times as much LDL but Ac-LDL uptake was increased by only 34%. This indicates that the Ac-LDL receptor is not down-regulated to the same extent as that for LDL. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Cell Science Pubmed

Differences in the uptake of modified low density lipoproteins by tissue cultured endothelial cells.

Gaffney, J; West, D; Arnold, F; Sattar, A; Kumar, S
Journal of Cell Science , Volume 79: 9 – Jun 9, 1986
Download PDF

Differences in the uptake of modified low density lipoproteins by tissue cultured endothelial cells.


Abstract

Acetylated low density lipoprotein (Ac-LDL) is taken up by bovine aortic and adrenal capillary cells but not by brain capillary cells. This indicates that the uptake of Ac-LDL is not a feature of all types of endothelial cell. A quantitative examination of lipoprotein uptake by flow cytometry showed cells in G2M took up 45% more Ac-LDL than those in G1S. Compared with confluent cultures, sub-confluent bovine aortic cells took up three times as much LDL but Ac-LDL uptake was increased by only 34%. This indicates that the Ac-LDL receptor is not down-regulated to the same extent as that for LDL.

Loading next page...
 
/lp/pubmed/differences-in-the-uptake-of-modified-low-density-lipoproteins-by-kOeTSarhyV

References

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

ISSN
0021-9533
DOI
10.1242/jcs.79.1.317
pmid
3833867

Abstract

Acetylated low density lipoprotein (Ac-LDL) is taken up by bovine aortic and adrenal capillary cells but not by brain capillary cells. This indicates that the uptake of Ac-LDL is not a feature of all types of endothelial cell. A quantitative examination of lipoprotein uptake by flow cytometry showed cells in G2M took up 45% more Ac-LDL than those in G1S. Compared with confluent cultures, sub-confluent bovine aortic cells took up three times as much LDL but Ac-LDL uptake was increased by only 34%. This indicates that the Ac-LDL receptor is not down-regulated to the same extent as that for LDL.

Journal

Journal of Cell Science – Pubmed

Published: Jun 9, 1986

There are no references for this article.