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References (51)
-
D. Latchman, J. Estridge, L. Kemp (1987)
Transcriptional induction of the ubiquitin gene during herpes simplex virus infection is dependent upon the viral immediate-early protein ICP4.Nucleic acids research, 15 18
-
(1988)
Ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of Parkinson’s disease, Pick‘s disease, and Alzheimer’s disease -
M. McKinley, A. Taraboulos, L. Kenaga, Dan Serban, A. Stieber, S. DeArmond, S. Prusiner, N. Gonatas (1991)
Ultrastructural localization of scrapie prion proteins in cytoplasmic vesicles of infected cultured cells.Laboratory investigation; a journal of technical methods and pathology, 65 6
-
B. Caughey, R. Race, D. Ernst, M. Buchmeier, B. Chesebro (1989)
Prion protein biosynthesis in scrapie-infected and uninfected neuroblastoma cellsJournal of Virology, 63
-
990) PCR Protocols. A Guide to Methods and Applications -
L. Laszlo, F. Doherty, N. Osborn, R. Mayer (1990)
Ubiquitinated protein conjugates are specifically enriched in the lysosomal system of fibroblastsFEBS Letters, 261
-
R. Mayer, J. Arnold, L. Laszlo, M. Landon, J. Lowe (1991)
Ubiquitin in health and disease.Biochimica et biophysica acta, 1089 2
-
982) Molecular Cloning: A Laboratory Manual -
Lutz Giebel, Bernd Dworniczak, E. Bautz (1988)
Developmental regulation of a constitutively expressed mouse mRNA encoding a 72-kDa heat shock-like protein.Developmental biology, 125 1
-
C. Borkird, C. Simoens, R. Villarroel, M. Montagu (1991)
Gene expression associated with water-stress adaptation of rice cells and identification of two genes as hsp 70 and ubiquitinPhysiologia Plantarum, 82
-
A. Taraboulos, D. Serban, S. Prusiner (1990)
Scrapie prion proteins accumulate in the cytoplasm of persistently infected cultured cellsThe Journal of Cell Biology, 110
-
H. Büeler, A. Aguzzi, A. Sailer, R. Greiner, P. Autenried, M. Aguet, C. Weissmann (1993)
Mice devoid of PrP are resistant to scrapieCell, 73
-
F. Sanger, S. Nicklen, A. Coulson (1977)
DNA sequencing with chain-terminating inhibitors.Proceedings of the National Academy of Sciences of the United States of America, 74 12
-
D. Borchelt, A. Taraboulos, S. Prusiner (1992)
Evidence for synthesis of scrapie prion proteins in the endocytic pathway.The Journal of biological chemistry, 267 23
-
S. Prusiner (1992)
Chemistry and biology of prions.Biochemistry, 31 49
-
K. Reed, D. Mann (1985)
Rapid transfer of DNA from agarose gels to nylon membranes.Nucleic acids research, 13 20
-
L. Laszlo, F. Doherty, A. Watson, T. Self, M. Landon, J. Lowe, R. Mayer (1991)
Immunogold localisation of ubiquitin‐protein conjugates in primary (azurophilic) granules of polymorphonuclear neutrophilsFEBS Letters, 279
-
Lajos Lázló, J. Tuckwell, T. Self, J. Lowe, M. Landon, Sharon Smith, J. Hawthorne, R. Mayer (1991)
The latent membrane protein‐1 in Epstein‐Barr virus‐transformed lymphoblastoid cells is found with ubiquitin‐protein conjugates and heat‐shock protein 70 in lysosomes oriented around the microtubule organizing centreThe Journal of Pathology, 164
-
U. Bond, M. Schlesinger (1985)
Ubiquitin is a heat shock protein in chicken embryo fibroblastsMolecular and Cellular Biology, 5
-
A. Müller-Taubenberger, J. Hagmann, A. Noegel, G. Gerisch (1988)
Ubiquitin gene expression in Dictyostelium is induced by heat and cold shock, cadmium, and inhibitors of protein synthesis.Journal of cell science, 90 ( Pt 1)
-
L. Singh, K. Jones (1984)
The use of heparin as a simple cost-effective means of controlling background in nucleic acid hybridization procedures.Nucleic acids research, 12 14
-
S. Jentsch, W. Seufert, H. Hauser (1991)
Genetic analysis of the ubiquitin system.Biochimica et biophysica acta, 1089 2
-
S. DeArmond, W. Mobley, D. Demott, R. Barry, J. Beckstead, S. Prusiner (1987)
Changes in the localization of brain prion proteins during scrapie infectionNeurology, 37
-
D. Finley, Engin Özkaynak, A. Varshavsky (1987)
The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation, and other stressesCell, 48
-
S. Prusiner (1991)
Molecular biology of prion diseasesScience, 252
-
P. Heggie, T. Burdon, J. Lowe, M. Landon, G. Lennox, D. Jefferson, R. Mayer (1989)
Ubiquitin gene expression in brain and spinal cord in motor neurone diseaseNeuroscience Letters, 102
-
F. Doherty, N. Osborn, J. Wassell, P. Heggie, L. Laszlo, R. Mayer (1989)
Ubiquitin-protein conjugates accumulate in the lysosomal system of fibroblasts treated with cysteine proteinase inhibitors.The Biochemical journal, 263 1
-
Bond (1985)
Ubiquitin is a heat-shock protein in chicken embryo fibroblastsMol. Cell. Biol., 5
-
(1993)
129 / 01 a mice carrying a null mutation in the PrP gene that abolishes mRNA production are developmentally normal -
P. Löw, F. Doherty, M. Sass, János Kovács, R. Mayer, L. Laszlo (1993)
Immunogold localisation of ubiquitin‐protein conjugates in Sf9 insect cellsFEBS Letters, 316
-
J. Finch, K. Bonham, P. Krieg, G. Bowden (1990)
Murine polyubiquitin mRNA sequence.Nucleic acids research, 18 7
-
Byron Caughey, G. Raymond, D. Ernst, R. Race (1991)
N-terminal truncation of the scrapie-associated form of PrP by lysosomal protease(s): implications regarding the site of conversion of PrP to the protease-resistant stateJournal of Virology, 65
-
P. Chomczyński, N. Sacchi (1987)
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.Analytical biochemistry, 162 1
-
J. Lowe, H. Mcdermott, N. Kenward, M. Landon, R. Mayer, M. Bruce, P. McBride, R. Somerville, J. Hope (1990)
Ubiquitin conjugate immunoreactivity in the brains of scrapie infected miceThe Journal of Pathology, 162
-
J. Hope, Laura Morton, C. Farquhar, Gerd Multhaupt, Konrad Beyreutherl, Richard, H. Kimberlin (1986)
The major polypeptide of scrapie‐associated fibrils (SAF) has the same size, charge distribution and N‐terminal protein sequence as predicted for the normal brain protein (PrP).The EMBO Journal, 5
-
M. Nenoi (1992)
Induced accumulation of polyubiquitin gene transcripts in HeLa cells after UV-irradiation and TPA-treatment.International journal of radiation biology, 61 2
-
H. Büeler, M. Fischer, Yolande Lang, H. Bluethmann, H. Lipp, S. DeArmond, S. Prusiner, M. Aguet, C. Weissmann (1992)
Normal development and behaviour of mice lacking the neuronal cell-surface PrP proteinNature, 356
-
Ove Wiborg, Marianne Pedersen, '. AnetteWind, Lars Berglund, Kjeld Marcker, Jens Vuust (1985)
The human ubiquitin multigene family: some genes contain multiple directly repeated ubiquitin coding sequences.The EMBO Journal, 4
-
James Lowe, R. Mayer, M. Landon (1993)
Ubiquitin in Neurodegenerative DiseasesBrain Pathology, 3
-
H. Fraser (1976)
The pathology of a natural and experimental scrapie.Frontiers of biology, 44
-
H. Fraser, R. H. Kimb (1976)
Slow Virus Diseases of Animals and Man -
A. Feinberg, B. Vogelstein (1983)
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.Analytical biochemistry, 132 1
-
H. Chiang, Terlecky, CP Plant, J. Dice (1989)
A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins.Science, 246 4928
-
F. Lazarini, J. Deslys, D. Dormont (1992)
Variations in prion protein and glial fibrillary acidic protein mRNAs in the brain of scrapie-infected newborn mouse.The Journal of general virology, 73 ( Pt 7)
-
J. Lowe, J. Fergusson, N. Kenward, L. Laszlo, M. Landon, C. Farquhar, John Brown, J. Hope, R. Mayer (1992)
Immunoreactivity to ubiquitin—protein conjugates is present early in the disease process in the brains of scrapie‐infected miceThe Journal of Pathology, 168
-
S. Saunders, J. Burke (1990)
Rapid isolation of miniprep DNA for double strand sequencing.Nucleic acids research, 18 16
-
Martin Jeffrey, C. Goodsir, Moira Bruce, P. McBride, J. Scott, W. Halliday (1992)
Infection specific prion protein (PrP) accumulates on neuronal plasmalemma in scrapie infected miceNeuroscience Letters, 147
-
Jia-Xiu Pan, S. Short, S. Goff, J. Dice (1993)
Ubiquitin pools, ubiquitin mRNA levels, and ubiquitin-mediated proteolysis in aging human fibroblastsExperimental Gerontology, 28
-
L. Laszlo, J. Lowe, T. Self, N. Kenward, M. Landon, Trisha McBride, C. Farquhar, I. Mcconnell, John Brown, J. Hope, R. Mayer (1992)
Lysosomes as key organelles in the pathogenesis of prion encephalopathiesThe Journal of Pathology, 166
-
A. Balmain, R. Krumlauf, J. Vass, G. Birnie (1982)
Cloning and characterisation of the abundant cytoplasmic 7S RNA from mouse cells.Nucleic acids research, 10 14
-
S. Terlecky, H. Chiang, T. Olson, J. Dice (1992)
Protein and peptide binding and stimulation of in vitro lysosomal proteolysis by the 73-kDa heat shock cognate protein.The Journal of biological chemistry, 267 13
- Publisher
- Wiley
- Copyright
- Copyright © 1994 Wiley Subscription Services
- ISSN
- 0022-3042
- eISSN
- 1471-4159
- DOI
- 10.1046/j.1471-4159.1994.62051870.x
- Publisher site
- See Article on Publisher Site
Abstract
Abstract: We have shown by northern analyses that the expression of the mouse polyubiquitin C gene is increased several fold in the brains of mice infected with both the ME7 and 87V strains of scrape. Expression of the polyubiquitin gene does not change significantly, compared with controls, until the later stages of disease progression when there is a 2.5‐fold increase in ME7‐infected brains and a 1.8‐fold increase in 87V‐infected brains. The patterns of changes of expression of the polyubiquitin genes in brains infected with the two strains of scrapie resemble those of accumulation of ubiquitin‐conjugate‐positive structures in the brain that are detected immunohisto chemically. A similar increase in the expression of a heatshock protein 70 gene also occurs.
Journal
Journal of Neurochemistry – Wiley
Published: Jan 1, 1994
Keywords: ; ; ; ;