S. Jamal, R. Schneider (2002)
UV-induction of keratinocyte endothelin-1 downregulates E-cadherin in melanocytes and melanoma cells.The Journal of clinical investigation, 110 4
(1973)
SEER (1998) SEER Cancer Statistics Review
Barbara Gilchrest, M. Eller, Alan Geller, M. Yaar (1999)
The pathogenesis of melanoma induced by ultraviolet radiation.The New England journal of medicine, 340 17
R. Zanetti, S. Franceschi, S. Rosso, S. Colonna, E. Bidoli (1992)
Cutaneous melanoma and sunburns in childhood in a southern European population.European journal of cancer, 28A 6-7
P. Pollock, J. Pearson, N. Hayward (1996)
Compilation of somatic mutations of the CDKN2 gene in human cancers: Non‐random distribution of base substitutionsGenes, 15
E. Atillasoy, J. Seykora, P. Soballe, R. Elenitsas, M. Nesbit, D. Elder, K. Montone, E. Sauter, M. Herlyn (1998)
UVB induces atypical melanocytic lesions and melanoma in human skin.The American journal of pathology, 152 5
N. Sharpless, N. Bardeesy, Kee‐Ho Lee, D. Carrasco, D. Castrillon, A. Aguirre, Emily Wu, J. Horner, R. DePinho (2001)
Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesisNature, 413
B. Williams, L. Remington, D. Albert, S. Mukai, R. Bronson, T. Jacks (1994)
Cooperative tumorigenic effects of germline mutations in Rb and p53Nature Genetics, 7
Simone Harrison, Richard Speare, I. Wronski, Robert MacLennan (1994)
Sun exposure and melanocytic naevi in young Australian childrenThe Lancet, 344
J. Flores, Graeme Walker, J. Glendening, F. Haluska, J. Castresana, Rubio Mp, Pastorfide Gc, Boyer La, W. Kao, M. Bulyk, Raymond Barnhill, Nicholas Hayward, David Housman, J. Fountain (1996)
Loss of the p16INK4a and p15INK4b genes, as well as neighboring 9p21 markers, in sporadic melanoma.Cancer research, 56 21
F. Noonan, J. Recio, H. Takayama, P. Duray, M. Anver, W. Rush, E. Fabo, G. Merlino (2001)
Neonatal sunburn and melanoma in miceNature, 413
S. Pavey, S. Conroy, Terry Russell, B. Gabrielli (1999)
Ultraviolet radiation induces p16CDKN2A expression in human skin.Cancer research, 59 17
B. Bastian, P. Leboit, Henning Hamm, E. Bröcker, D. Pinkel (1998)
Chromosomal gains and losses in primary cutaneous melanomas detected by comparative genomic hybridization.Cancer research, 58 10
C. Berking, Richelle Takemoto, R. Binder, S. Hartman, D. Ruiter, P. Gallagher, S. Lessin, M. Herlyn (2002)
Photocarcinogenesis in human adult skin grafts.Carcinogenesis, 23 1
H. Davies, G. Bignell, Charles Cox, P. Stephens, S. Edkins, S. Clegg, J. Teague, H. Woffendin, Mathew Garnett, W. Bottomley, Neil Davis, E. Dicks, Rebecca Ewing, Yvonne Floyd, K. Gray, S. Hall, R. Hawes, Jaime Hughes, Vivian Kosmidou, A. Menzies, Catherine Mould, A. Parker, C. Stevens, S. Watt, S. Hooper, Rebecca Wilson, H. Jayatilake, B. Gusterson, C. Cooper, J. Shipley, D. Hargrave, K. Pritchard-Jones, N. Maitland, G. Chenevix-Trench, G. Riggins, D. Bigner, G. Palmieri, A. Cossu, A. Flanagan, A. Nicholson, Judy Ho, Suet Leung, S. Yuen, Barbara Weber, H. Seigler, T. Darrow, H. Paterson, R. Marais, Christopher Marshall, R. Wooster, Michael Stratton, P. Futreal (2002)
Mutations of the BRAF gene in human cancerNature, 417
F. Stott, S. Bates, M. James, B. McConnell, M. Starborg, S. Brookes, I. Palmero, K. Ryan, E. Hara, K. Vousden, G. Peters (1998)
The alternative product from the human CDKN2A locus, p14ARF, participates in a regulatory feedback loop with p53 and MDM2The EMBO Journal, 17
H. Rizos, S. Puig, C. Badenas, J. Malvehy, A. Darmanian, L. Jiménez, M. Milá, R. Kefford (2001)
A melanoma-associated germline mutation in exon 1β inactivates p14ARFOncogene, 20
N. Bardeesy, B. Bastian, A. Hezel, D. Pinkel, R. DePinho, L. Chin (2001)
Dual Inactivation of RB and p53 Pathways in RAS-Induced MelanomasMolecular and Cellular Biology, 21
Shireen Khan, Janet Moritsugu, G. Wahl (2000)
Differential requirement for p19ARF in the p53-dependent arrest induced by DNA damage, microtubule disruption, and ribonucleotide depletionProceedings of the National Academy of Sciences of the United States of America, 97
Michael Fitzgerald, D. Harkin, Sandra Arrieta, Deborah Macdonald, Leslie LUCCHINAt, Hilal Unsal, Erin O'NEILL, Jim Koh, Dianne FINKELSTEINt, K. Isselbacher, Arthur SOBERt, Daniel Haber (1996)
Prevalence of germ-line mutations in p16, p19ARF, and CDK4 in familial melanoma: analysis of a clinic-based population.Proceedings of the National Academy of Sciences of the United States of America, 93 16
L. Chin, J. Pomerantz, D. Polsky, D. Polsky, M. Jacobson, Carlos Cohen, C. Cordon-Cardo, J. Horner, R. DePinho (1997)
Cooperative effects of INK4a and ras in melanoma susceptibility in vivo.Genes & development, 11 21
N. Sharpless, Scott Alson, Suzanne Chan, D. Silver, D. Castrillon, R. DePinho (2002)
p16(INK4a) and p53 deficiency cooperate in tumorigenesis.Cancer research, 62 10
N. Sharpless, R. DePinho (1999)
The INK4A/ARF locus and its two gene products.Current opinion in genetics & development, 9 1
M. Herlyn, K. Satyamoorthy (1996)
Activated ras. Yet another player in melanoma?The American journal of pathology, 149 3
N. Sharpless, D. Ferguson, R. O'Hagan, D. Castrillon, Charles Lee, P. Farazi, Scott Alson, James Fleming, C. Morton, Karen Frank, Karen Frank, L. Chin, F. Alt, R. DePinho (2001)
Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions.Molecular cell, 8 6
T. Kamijo, F. Zindy, M. Roussel, D. Quelle, J. Downing, R. Ashmun, G. Grosveld, C. Sherr (1997)
Tumor Suppression at the Mouse INK4a Locus Mediated by the Alternative Reading Frame Product p19 ARFCell, 91
R. Fåhraeus, D. Lane (1999)
The p16INK4a tumour suppressor protein inhibits αvβ3 integrin‐mediated cell spreading on vitronectin by blocking PKC‐dependent localization of αvβ3 to focal contactsThe EMBO Journal, 18
L. Tang, G. Li, V. Tron, M. Trotter, V. Ho (1999)
Expression of cell cycle regulators in human cutaneous malignant melanoma.Melanoma research, 9 2
P. Markel, P. Shu, C. Ebeling, G. Carlson, D. Nagle, J. Smutko, K. Moore (1997)
Theoretical and empirical issues for marker-assisted breeding of congenic mouse strainsNature Genetics, 17
F. Gruijl, H. Kranen, L. Mullenders (2001)
UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancer.Journal of photochemistry and photobiology. B, Biology, 63 1-3
M. Ruas, G. Peters (1998)
The p16INK4a/CDKN2A tumor suppressor and its relatives.Biochimica et biophysica acta, 1378 2
P. Krimpenfort, K. Quon, W. Mooi, Ate Loonstra, A. Berns (2001)
Loss of p16Ink4a confers susceptibility to metastatic melanoma in miceNature, 413
G. Walker, J. Flores, J. Glendening, A. Lin, I. Markl, J. Fountain (1998)
Virtually 100% of melanoma cell lines harbor alterations at the DNA level within CDKN2A, CDKN2B, or one of their downstream targetsGenes, 22
C. Donawho, M. Kripke (1991)
Evidence that the local effect of ultraviolet radiation on the growth of murine melanomas is immunologically mediated.Cancer research, 51 16
M. Piepkorn (2000)
The expression of p16(INK4a), the product of a tumor suppressor gene for melanoma, is upregulated in human melanocytes by UVB irradiation.Journal of the American Academy of Dermatology, 42 5 Pt 1
J. Randerson-Moor, M. Harland, Sarah Williams, D. Cuthbert-Heavens, E. Sheridan, J. Aveyard, Kathryn Sibley, L. Whitaker, M. Knowles, J. Bishop, D. Bishop (2001)
A germline deletion of p14(ARF) but not CDKN2A in a melanoma-neural system tumour syndrome family.Human molecular genetics, 10 1
A. Kamb, N. Gruis, J. Weaver-Feldhaus, Qingyun Liu, K. Harshman, S. Tavtigian, E. Stockert, R. Day, B. Johnson, M. Skolnick, M. Skolnick (1994)
A cell cycle regulator potentially involved in genesis of many tumor types.Science, 264 5157
K. Peris, S. Chimenti, M. Fargnoli, P. Valeri, H. Kerl, P. Wolf (1999)
UV fingerprint CDKN2a but no p14ARF mutations in sporadic melanomas.The Journal of investigative dermatology, 112 5
M. Horiguchi, K. Masumura, H. Ikehata, Tetsuya Ono, Yusuke Kanke, Takehiko Nohmi (2001)
Molecular nature of ultraviolet B light-induced deletions in the murine epidermis.Cancer research, 61 10
T. Kamijo, S. Bodner, E. Kamp, D. Randle, C. Sherr (1999)
Tumor spectrum in ARF-deficient mice.Cancer research, 59 9
L. Chin, G. Merlino, R. DePinho (1998)
Malignant melanoma: modern black plague and genetic black box.Genes & development, 12 22
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