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References (30)
-
Xia Yang, E. Schadt, Susanna Wang, Hui Wang, A. Arnold, L. Ingram-drake, T. Drake, A. Lusis (2006)
Tissue-specific expression and regulation of sexually dimorphic genes in mice.Genome research, 16 8
-
Y. Kanfi, Victoria Peshti, Reuven Gil, Shoshana Naiman, Liat Nahum, E. Levin, N. Kronfeld-Schor, H. Cohen (2010)
SIRT6 protects against pathological damage caused by diet‐induced obesityAging Cell, 9
-
Phillip Lee, L. Giudice, C. Conover, D. Powell (1997)
Insulin-like Growth Factor Binding Protein-1: Recent Findings and New DirectionsProceedings of the Society for Experimental Biology and Medicine, 216
-
R. Scott, J. Hahn, S. Doniach, H. Freeman, K. Hodgson, A. Flank, M. Weininger, L. Mortenson, S. Cramer, R. Debus, M. Strickler, Lee Walker, W. Hillier, Y. Kimura, N. Mizusawa, T. Yamanari, A. Ishii, T. Ono (2006)
Transgenic Mice with a Reduced Core Body Temperature Have an Increased Life Span -
(2001)
Significance analysis of microarrays applied to the ionizing radiation response -
Matthias Bauer, A. Hamm, Melanie Bonaus, Andrea Jacob, J. Jaekel, H. Schorle, M. Pankratz, Joerg Katzenberger (2004)
Starvation response in mouse liver shows strong correlation with life-span-prolonging processes.Physiological genomics, 17 2
-
Camilla Burnett, S. Valentini, F. Cabreiro, M. Goss, Milán Somogyvári, M. Piper, Matthew Hoddinott, G. Sutphin, Vid Leko, J. McElwee, Rafael Vázquez, Anne-Marie Orfila, D. Ackerman, Catherine Au, G. Vinti, Michèle Riesen, K. Howard, C. Néri, A. Bedalov, M. Kaeberlein, C. Söti, L. Partridge, D. Gems (2011)
Absence of effects of Sir2 over-expression on lifespan in C. elegans and DrosophilaNature, 477
-
Shaday Michán, D. Sinclair (2007)
Sirtuins in mammals: insights into their biological function.The Biochemical journal, 404 1
-
J. Baur, Danica Chen, E. Chini, Katrin Chua, H. Cohen, R. Cabo, C. Deng, S. Dimmeler, D. Gius, L. Guarente, S. Helfand, S. Imai, H. Itoh, T. Kadowaki, D. Koya, C. Leeuwenburgh, M. McBurney, Y. Nabeshima, C. Néri, Philipp Oberdoerffer, R. Pestell, B. Rogina, J. Sadoshima, V. Sartorelli, M. Serrano, D. Sinclair, C. Steegborn, M. Tatar, H. Tissenbaum, Q. Tong, K. Tsubota, A. Vaquero, E. Verdin (2010)
Dietary restriction: standing up for sirtuins.Science, 329 5995
-
Tiara Kawahara, E. Michishita, A. Adler, M. Damian, Elisabeth Berber, Meihong Lin, R. McCord, K. Ongaigui, Lisa Boxer, Howard Chang, Katrin Chua (2009)
SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life SpanCell, 136
-
C. Selman, N. Kerrison, A. Cooray, M. Piper, Steven Lingard, R. Barton, E. Schuster, E. Blanc, D. Gems, J. Nicholson, J. Thornton, L. Partridge, D. Withers (2006)
Coordinated multitissue transcriptional and plasma metabonomic profiles following acute caloric restriction in mice.Physiological genomics, 27 3
-
Bu Yeap, S. Chubb, Ken Ho, Johnson Setoh, Kieran McCaul, Paul Norman, K. Jamrozik, L. Flicker (2010)
IGF1 and its binding proteins 3 and 1 are differentially associated with metabolic syndrome in older men.European journal of endocrinology, 162 2
-
C Burnett (2011)
Absence of effects of Sir2 overexpression on lifespan in C. elegans and DrosophilaNature, 477
-
Gizem Rizki, Terri Iwata, Ji Li, C. Riedel, Colette Picard, Max Jan, C. Murphy, Siu Lee (2011)
The Evolutionarily Conserved Longevity Determinants HCF-1 and SIR-2.1/SIRT1 Collaborate to Regulate DAF-16/FOXOPLoS Genetics, 7
-
Rong Yuan, Shirng-Wern Tsaih, Stefka Petkova, Caralina Evsikova, Shuqin Xing, M. Marion, M. Bogue, K. Mills, L. Peters, C. Bult, C. Rosen, J. Sundberg, D. Harrison, G. Churchill, B. Paigen (2009)
Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levelsAging Cell, 8
-
D. Herranz, Maribel Muñoz-Martín, M. Cañamero, F. Mulero, Bárbara Martínez-Pastor, O. Fernandez-Capetillo, M. Serrano (2010)
Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer.Nature communications, 1
-
Y. Kanfi, Victoria Peshti, Yosi Gozlan, Moran Rathaus, Reuven Gil, H. Cohen (2008)
Regulation of SIRT1 protein levels by nutrient availabilityFEBS Letters, 582
-
M Viswanathan, L Guarente (2011)
Regulation of Caenorhabditis elegans lifespan by sir-2. 1 transgenesNature, 477
-
W. Swindell (2009)
Genes and gene expression modules associated with caloric restriction and aging in the laboratory mouseBMC Genomics, 10
-
(2007)
Recent Findings and New Directions -
V. Katuri, A. Dillner, Bibhuti Mishra, Chu-Xia Deng, Lopa Mishra (2003)
Extended Longevity in Mice Lacking the Insulin Receptor in Adipose TissueScience, 299
-
Y. Kanfi, Ronnie Shalman, Victoria Peshti, Shmuel Pilosof, Y. Gozlan, K. Pearson, B. Lerrer, D. Moazed, J. Marine, R. Cabo, H. Cohen (2008)
Regulation of SIRT6 protein levels by nutrient availabilityFEBS Letters, 582
-
M. Viswanathan, L. Guarente (2011)
Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenesNature, 477
-
Preston Estep, J. Warner, M. Bulyk (2009)
Short-Term Calorie Restriction in Male Mice Feminizes Gene Expression and Alters Key Regulators of Conserved Aging Regulatory PathwaysPLoS ONE, 4
-
M. Holzenberger, J. Dupont, B. Ducos, P. Leneuve, A. Géloën, P. Even, P. Cervera, Y. Bouc (2003)
IGF-1 receptor regulates lifespan and resistance to oxidative stress in miceNature, 421
-
D. Harrison, R. Strong, Z. Sharp, James Nelson, C. Astle, K. Flurkey, N. Nadon, J. Wilkinson, K. Frenkel, C. Carter, C. Carter, M. Pahor, M. Pahor, M. Javors, Elizabeth Fernandez, Richard Miller (2009)
Rapamycin fed late in life extends lifespan in genetically heterogeneous miceNature, 460
-
C. Selman, Jennifer Tullet, Daniela Wieser, E. Irvine, Steven Lingard, A. Choudhury, M. Claret, Hind Al-Qassab, D. Carmignac, F. Ramadani, A. Woods, I. Robinson, E. Schuster, R. Batterham, S. Kozma, G. Thomas, D. Carling, K. Okkenhaug, J. Thornton, L. Partridge, D. Gems, D. Withers (2009)
Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life SpanScience, 326
-
Chenxi Wang, Qing Li, D. Redden, R. Weindruch, D. Allison (2004)
Statistical methods for testing effects on “maximum lifespan”Mechanisms of Ageing and Development, 125
-
R. Mostoslavsky, Katrin Chua, D. Lombard, Wendy Pang, Miriam Fischer, L. Gellon, Pingfang Liu, G. Mostoslavsky, S. Franco, Michael Murphy, Kevin Mills, Parin Patel, Joyce Hsu, Andrew Hong, E. Ford, Hwei-Ling Cheng, Caitlin Kennedy, Nomeli Nunez, R. Bronson, D. Frendewey, W. Auerbach, D. Valenzuela, M. Karow, M. Hottiger, S. Hursting, J. Barrett, L. Guarente, R. Mulligan, B. Demple, G. Yancopoulos, Frederick Alt (2006)
Genomic Instability and Aging-like Phenotype in the Absence of Mammalian SIRT6Cell, 124
-
C. Kenyon (2010)
The genetics of ageingNature, 464
- Publisher
- Springer Journals
- Copyright
- Copyright © 2012 by Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.
- Subject
- Science, Humanities and Social Sciences, multidisciplinary; Science, Humanities and Social Sciences, multidisciplinary; Science, multidisciplinary
- ISSN
- 0028-0836
- eISSN
- 1476-4687
- DOI
- 10.1038/nature10815
- Publisher site
- See Article on Publisher Site
Abstract
The role of sirtuins in longevity is controversial, and little is known about mammalian sirtuins; now, male mice that overexpress SIRT6 are shown to have a longer lifespan than wild-type mice, unlike their female counterparts.
Journal
Nature – Springer Journals
Published: Feb 22, 2012