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C. Feng, Carmen Collazo-Custodio, M. Eckhaus, S. Hieny, Y. Belkaid, K. Elkins, Dragana Jankovic, G. Taylor, A. Sher (2004)
Mice Deficient in LRG-47 Display Increased Susceptibility to Mycobacterial Infection Associated with the Induction of LymphopeniaThe Journal of Immunology, 172
Gerrit Praefcke, H. McMahon (2004)
The dynamin superfamily: universal membrane tubulation and fission molecules?Nature Reviews Molecular Cell Biology, 5
Revathy Uthaiah, Gerrit Praefcke, J. Howard, C. Herrmann (2003)
IIGP1, an Interferon-γ-inducible 47-kDa GTPase of the Mouse, Showing Cooperative Enzymatic Activity and GTP-dependent Multimerization*Journal of Biological Chemistry, 278
Maria Traver, S. Henry, V. Cantillana, T. Oliver, Julia Hunn, J. Howard, S. Beer, K. Pfeffer, J. Coers, G. Taylor (2011)
Immunity-related GTPase M (IRGM) Proteins Influence the Localization of Guanylate-binding Protein 2 (GBP2) by Modulating MacroautophagyThe Journal of Biological Chemistry, 286
Michael Schnoor, Abigail Betanzos, Dominique Weber, C. Parkos (2009)
Guanylate-binding protein-1 is expressed at tight junctions of intestinal epithelial cells in response to interferon-γ and regulates barrier function through effects on apoptosisMucosal Immunology, 2
Sarah Fentress, Michael Behnke, I. Dunay, M. Mashayekhi, Leah Rommereim, B. Fox, D. Bzik, G. Taylor, G. Taylor, B. Turk, Cheryl Lichti, R. Townsend, W. Qiu, R. Hui, W. Beatty, L. Sibley (2010)
Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence.Cell host & microbe, 8 6
J. Coers, I. Bernstein-Hanley, David Grotsky, I. Parvanova, J. Howard, G. Taylor, W. Dietrich, M. Starnbach (2008)
Chlamydia muridarum Evades Growth Restriction by the IFN-γ-Inducible Host Resistance Factor Irgb101The Journal of Immunology, 180
L. Bougnères, J. Helft, S. Tiwari, Pablo Vargas, B. Chang, L. Chan, L. Campisi, G. Lauvau, S. Hugues, Pradeep Kumar, Alice Kamphorst, Ana-Maria Dumenil, M. Nussenzweig, J. MacMicking, S. Amigorena, P. Guermonprez (2009)
A role for lipid bodies in the cross-presentation of phagocytosed antigens by MHC class I in dendritic cells.Immunity, 31 2
B. Beutler, Zhengfan Jiang, P. Georgel, K. Crozat, B. Croker, S. Rutschmann, Xin Du, K. Hoebe (2006)
Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large.Annual review of immunology, 24
J. Marquis, Oxana Kapoustina, D. Langlais, R. Ruddy, C. Dufour, B. Kim, J. MacMicking, V. Giguère, P. Gros (2011)
Interferon Regulatory Factor 8 Regulates Pathways for Antigen Presentation in Myeloid Cells and during TuberculosisPLoS Genetics, 7
Craddock (2010)
713Nature, 464
Christopher Dupont, C. Hunter (2012)
Guanylate-binding proteins: niche recruiters for antimicrobial effectors.Immunity, 37 2
Yasuhiro Itsui, N. Sakamoto, S. Kakinuma, M. Nakagawa, Yuko Sekine‐Osajima, Megumi Tasaka-Fujita, Yuki Nishimura‐Sakurai, G. Suda, Yuko Karakama, Kako Mishima, Machi Yamamoto, Takako Watanabe, Mayumi Ueyama, Yusuke Funaoka, Seishin Azuma, Mamoru Watanabe (2009)
Antiviral effects of the interferon‐induced protein guanylate binding protein 1 and its interaction with the hepatitis C virus NS5B proteinHepatology, 50
M. Gutierrez, Sharon Master, Sudha Singh, G. Taylor, M. Colombo, V. Deretic (2004)
Autophagy Is a Defense Mechanism Inhibiting BCG and Mycobacterium tuberculosis Survival in Infected MacrophagesCell, 119
Kouji Matsumoto, Jin Kusaka, A. Nishibori, H. Hara (2006)
Lipid domains in bacterial membranesMolecular Microbiology, 61
Masahiro Yamamoto, M. Okuyama, Ji Ma, Taishi Kimura, Naganori Kamiyama, H. Saiga, J. Ohshima, Miwa Sasai, H. Kayama, T. Okamoto, D. Huang, Dominique Soldati-Favre, K. Horie, J. Takeda, K. Takeda (2012)
A cluster of interferon-γ-inducible p65 GTPases plays a critical role in host defense against Toxoplasma gondii.Immunity, 37 2
Daniel Caffrey, K. Fitzgerald (2012)
Select Inflammasome AssemblyScience, 336
S. Mccarroll, A. Huett, Petric Kuballa, S. Chilewski, Aimee Landry, P. Goyette, M. Zody, Jennifer Hall, S. Brant, Judy Cho, R. Duerr, M. Silverberg, K. Taylor, J. Rioux, D. Altshuler, M. Daly, R. Xavier (2008)
Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's diseaseNature Genetics, 40
Nir Modiano, Yanping Lu, P. Cresswell (2005)
Golgi targeting of human guanylate-binding protein-1 requires nucleotide binding, isoprenylation, and an IFN-gamma-inducible cofactor.Proceedings of the National Academy of Sciences of the United States of America, 102 24
B. Prakash, Gerrit Praefcke, L. Renault, A. Wittinghofer, C. Herrmann (2000)
Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteinsNature, 403
Yun Ling, Michael Shaw, Carol Ayala, I. Coppens, G. Taylor, D. Ferguson, G. Yap (2006)
Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophagesThe Journal of Experimental Medicine, 203
Cemalettin Bekpen, Tomàs Marquès-Bonet, C. Alkan, F. Antonacci, Maria Leogrande, M. Ventura, J. Kidd, P. Siswara, J. Howard, E. Eichler (2009)
Death and Resurrection of the Human IRGM GenePLoS Genetics, 5
T. Klamp, U. Boehm, D. Schenk, K. Pfeffer, J. Howard (2003)
A Giant GTPase, Very Large Inducible GTPase-1, Is Inducible by IFNs 1The Journal of Immunology, 171
P. Burton, D. Clayton, L. Cardon, N. Craddock, P. Deloukas, A. Duncanson, D. Kwiatkowski, M. McCarthy, W. Ouwehand, N. Samani, J. Todd, P. Donnelly, J. Barrett, D. Davison, D. Easton, David Evans, H. Leung, J. Marchini, A. Morris, C. Spencer, M. Tobin, A. Attwood, J. Boorman, B. Cant, Ursula Everson, Judith Hussey, J. Jolley, A. Knight, K. Koch, Elizabeth Meech, S. Nutland, C. Prowse, H. Stevens, N. Taylor, G. Walters, N. Walker, N. Watkins, T. Winzer, Richard Jones, W. McArdle, S. Ring, D. Strachan, M. Pembrey, G. Breen, D. Clair, S. Caesar, K. Gordon-Smith, L. Jones, C. Fraser, E. Green, D. Grozeva, M. Hamshere, P. Holmans, I. Jones, G. Kirov, V. Moskvina, I. Nikolov, M. O’Donovan, M. Owen, D. Collier, A. Elkin, A. Farmer, R. Williamson, P. McGuffin, A. Young, I. Ferrier, S. Ball, A. Balmforth, J. Barrett, D. Bishop, M. Iles, A. Maqbool, N. Yuldasheva, A. Hall, P. Braund, R. Dixon, M. Mangino, Suzanne Stevens, J. Thompson, F. Bredin, M. Tremelling, M. Parkes, H. Drummond, C. Lees, E. Nimmo, J. Satsangi, S. Fisher, A. Forbes, C. Lewis, Clive Onnie, N. Prescott, J. Sanderson, C. Mathew, J. Barbour, M. Mohiuddin, C. Todhunter, J. Mansfield, T. Ahmad, Fraser Cummings, D. Jewell, J. Webster, Morris Brown, G. Lathrop, J. Connell, A. Dominiczak, C. Marcano, B. Burke, R. Dobson, J. Gungadoo, Kate Lee, P. Munroe, S. Newhouse, Abiodun Onipinla, C. Wallace, M. Xue, M. Caulfield, M. Farrall, A. Barton, I. Bruce, Hannah Donovan, S. Eyre, Paul Gilbert, S. Hider, A. Hinks, S. John, C. Potter, A. Silman, D. Symmons, W. Thomson, Jane Worthington, D. Dunger, B. Widmer, T. Frayling, R. Freathy, H. Lango, J. Perry, B. Shields, M. Weedon, A. Hattersley, G. Hitman, M. Walker, K. Elliott, C. Groves, C. Lindgren, N. Rayner, N. Timpson, E. Zeggini, M. Newport, G. Sirugo, Emily Lyons, F. Vannberg, A. Hill, L. Bradbury, C. Farrar, J. Pointon, Paul Wordsworth, M. Brown, J. Franklyn, J. Heward, M. Simmonds, S. Gough, S. Seal, M. Stratton, N. Rahman, M. Ban, A. Goris, S. Sawcer, Alastair Compston, D. Conway, M. Jallow, K. Rockett, S. Bumpstead, Amy Chaney, K. Downes, Mohammed Ghori, R. Gwilliam, S. Hunt, M. Inouye, Andrew Keniry, E. King, R. McGinnis, Simon Potter, R. Ravindrarajah, P. Whittaker, Claire Widden, D. Withers, Niall Cardin, T. Ferreira, Joanne Pereira-Gale, Ingileif Hallgrímsdóttir, Bryan Howie, Z. Su, Y. Teo, Damjan Vukcevic, D. Bentley, A. Compston (2007)
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controlsNature, 447
Aliaksandr Khaminets, Julia Hunn, S. Könen-Waisman, Yang Zhao, D. Preukschat, J. Coers, J. Boyle, Y. Ong, J. Boothroyd, Gabriela Reichmann, J. Howard (2010)
Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuoleCellular Microbiology, 12
H. Saka, R. Valdivia (2012)
Emerging roles for lipid droplets in immunity and host-pathogen interactions.Annual review of cell and developmental biology, 28
Sebastian Winter, W. Niedelman, K. Jensen, E. Rosowski, Lindsay Julien, E. Spooner, Kacey Caradonna, B. Burleigh, J. Saeij, H. Ploegh, Eva-Maria Frickel (2011)
Determinants of GBP Recruitment to Toxoplasma gondii Vacuoles and the Parasitic Factors That Control ItPLoS ONE, 6
J. Mirpuri, J. Brazil, Andrew Berardinelli, T. Nasr, Kiesha Cooper, M. Schnoor, P. Lin, C. Parkos, N. Louis (2010)
Commensal Escherichia coli Reduces Epithelial Apoptosis through IFN-αA–Mediated Induction of Guanylate Binding Protein-1 in Human and Murine Models of Developing IntestineThe Journal of Immunology, 184
W. Heo, Takanari Inoue, W. Park, Man Kim, Byung Park, T. Wandless, T. Meyer (2006)
PI(3,4,5)P3 and PI(4,5)P2 Lipids Target Proteins with Polybasic Clusters to the Plasma MembraneScience, 314
Sudha Singh, Wojciech Ornatowski, I. Vergne, J. Naylor, Mônica Delgado, Esteban Roberts, Marisa Ponpuak, Sharon Master, Manohar Pilli, E. White, M. Komatsu, V. Deretic (2010)
Human IRGM Regulates Autophagy and Its Cell-Autonomous Immunity Functions Through MitochondriaNature cell biology, 12
Nan Yan, Zhijian Chen (2012)
Intrinsic antiviral immunityNature Immunology, 13
C. Nathan (2012)
Fresh Approaches to Anti-Infective TherapiesScience Translational Medicine, 4
R. Gasper, S. Meyer, K. Gotthardt, M. Sirajuddin, A. Wittinghofer (2009)
It takes two to tango: regulation of G proteins by dimerizationNature Reviews Molecular Cell Biology, 10
A. Rupper, J. Cardelli (2008)
Induction of Guanylate Binding Protein 5 by Gamma Interferon Increases Susceptibility to Salmonella enterica Serovar Typhimurium-Induced Pyroptosis in RAW 264.7 CellsInfection and Immunity, 76
Sascha Martens, J. Howard (2006)
The interferon-inducible GTPases.Annual review of cell and developmental biology, 22
J. MacMicking, G. Taylor, J. Mckinney (2003)
Immune Control of Tuberculosis by IFN-γ-Inducible LRG-47Science, 302
Cemalettin Bekpen, Julia Hunn, C. Rohde, I. Parvanova, L. Guethlein, D. Dunn, E. Glowalla, M. Leptin, J. Howard (2005)
The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineageGenome Biology, 6
M. Wehner, C. Herrmann (2010)
Biochemical properties of the human guanylate binding protein 5 and a tumor‐specific truncated splice variantThe FEBS Journal, 277
M. Parkes, J. Barrett, N. Prescott, M. Tremelling, C. Anderson, S. Fisher, R. Roberts, E. Nimmo, Fraser Cummings, D. Soars, H. Drummond, C. Lees, S. Khawaja, R. Bagnall, D. Burke, Catherine Todhunter, Tariq Ahmad, Clive Onnie, W. McArdle, D. Strachan, G. Bethel, C. Bryan, C. Lewis, P. Deloukas, A. Forbes, J. Sanderson, D. Jewell, J. Satsangi, J. Mansfield, L. Cardon, C. Mathew (2007)
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibilityNature Genetics, 39
J. Colicelli (2004)
Human RAS Superfamily Proteins and Related GTPasesScience's STKE, 2004
E. Kravets, D. Degrandi, S. Weidtkamp‐Peters, Britta Ries, Carolin Konermann, S. Felekyan, Julia Dargazanli, Gerrit Praefcke, C. Seidel, L. Schmitt, S. Smits, K. Pfeffer (2012)
The GTPase Activity of Murine Guanylate-binding Protein 2 (mGBP2) Controls the Intracellular Localization and Recruitment to the Parasitophorous Vacuole of Toxoplasma gondii*The Journal of Biological Chemistry, 287
J. MacMicking (2004)
IFN-inducible GTPases and immunity to intracellular pathogens.Trends in immunology, 25 11
A. Shenoy, David Wellington, Pradeep Kumar, Hilina Kassa, C. Booth, P. Cresswell, J. MacMicking (2012)
GBP5 Promotes NLRP3 Inflammasome Assembly and Immunity in MammalsScience, 336
Sascha Martens, K. Sabel, R. Lange, Revathy Uthaiah, E. Wolf, J. Howard (2004)
Mechanisms Regulating the Positioning of Mouse p47 Resistance GTPases LRG-47 and IIGP1 on Cellular Membranes: Retargeting to Plasma Membrane Induced by Phagocytosis1The Journal of Immunology, 173
Alexandra Nordmann, L. Wixler, Yvonne Boergeling, V. Wixler, S. Ludwig (2012)
A new splice variant of the human guanylate‐binding protein 3 mediates anti‐influenza activity through inhibition of viral transcription and replicationThe FASEB Journal, 26
I. Grégoire, C. Richetta, L. Meyniel-Schicklin, Sophie Borel, F. Pradezynski, Olivier Diaz, Alexandre Deloire, O. Azocar, J. Baguet, M. Breton, P. Mangeot, V. Navratil, Pierre-Emmanuel Joubert, M. Flacher, P. Vidalain, P. André, V. Lotteau, M. Biard-Piechaczyk, C. Rabourdin-Combe, M. Faure (2011)
IRGM Is a Common Target of RNA Viruses that Subvert the Autophagy NetworkPLoS Pathogens, 7
Christopher Capaldo, N. Beeman, R. Hilgarth, Porfirio Nava, N. Louis, E. Naschberger, M. Stürzl, C. Parkos, A. Nusrat (2012)
IFN-γ and TNF-α induced GBP-1 inhibits epithelial cell proliferation through suppression of β-catenin/TCF signalingMucosal immunology, 5
A. Kresse, Carolin Konermann, D. Degrandi, Cornelia Beuter-Gunia, J. Wuerthner, K. Pfeffer, S. Beer (2008)
Analyses of murine GBP homology clusters based on in silico, in vitro and in vivo studiesBMC Genomics, 9
L. Hernandez, K. Hueffer, M. Wenk, J. Galán (2004)
Salmonella Modulates Vesicular Traffic by Altering Phosphoinositide MetabolismScience, 304
A. Shenoy, B. Kim, Han-Pil Choi, Takeshi Matsuzawa, S. Tiwari, J. MacMicking (2008)
Emerging themes in IFN-γ-induced macrophage immunity by the p47 and p65 GTPase FamiliesImmunobiology, 212
Yang Zhao, Aliaksandr Khaminets, Julia Hunn, J. Howard (2009)
Disruption of the Toxoplasma gondii Parasitophorous Vacuole by IFNγ-Inducible Immunity-Related GTPases (IRG Proteins) Triggers Necrotic Cell DeathPLoS Pathogens, 5
J. MacMicking (2012)
Interferon-inducible effector mechanisms in cell-autonomous immunityNature Reviews. Immunology, 12
K. King, Justin Lew, Ngan Ha, Jeffery Lin, Xin Ma, E. Graviss, M. Goodell (2011)
Polymorphic Allele of Human IRGM1 Is Associated with Susceptibility to Tuberculosis in African AmericansPLoS ONE, 6
Natasa Papic, Julia Hunn, N. Pawlowski, J. Zerrahn, J. Howard (2008)
Inactive and Active States of the Interferon-inducible Resistance GTPase, Irga6, in VivoThe Journal of Biological Chemistry, 283
N. Britzen-Laurent, M. Bauer, Valeria Berton, N. Fischer, A. Syguda, Simone Reipschläger, E. Naschberger, C. Herrmann, M. Stürzl (2010)
Intracellular Trafficking of Guanylate-Binding Proteins Is Regulated by Heterodimerization in a Hierarchical MannerPLoS ONE, 5
Maureen Olszewski, J. Gray, D. Vestal (2006)
In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters.Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 26 5
P. Ronald, B. Beutler (2010)
Plant and Animal Sensors of Conserved Microbial SignaturesScience, 330
M. Berry, C. Graham, Finlay Mcnab, Zhaohui Xu, S. Bloch, T. Oni, K. Wilkinson, R. Banchereau, Jason Skinner, R. Wilkinson, Charlie Quinn, D. Blankenship, R. Dhawan, J. Cush, A. Mejías, O. Ramilo, O. Kon, V. Pascual, J. Banchereau, D. Chaussabel, A. O’Garra (2010)
An Interferon-Inducible Neutrophil-Driven Blood Transcriptional Signature in Human TuberculosisNature, 466
D. Nelson, D. Virok, H. Wood, C. Roshick, Raymond Johnson, W. Whitmire, D. Crane, O. Steele‐Mortimer, L. Kari, G. Mcclarty, H. Caldwell (2005)
Chlamydial IFN-γ immune evasion is linked to host infection tropismProceedings of the National Academy of Sciences of the United States of America, 102
D. Degrandi, Carolin Konermann, Cornelia Beuter-Gunia, A. Kresse, J. Würthner, Stefanie Kurig, S. Beer, K. Pfeffer (2007)
Extensive Characterization of IFN-Induced GTPases mGBP1 to mGBP10 Involved in Host Defense1The Journal of Immunology, 179
Song Gao, Alexander Malsburg, Alexej Dick, K. Faelber, G. Schröder, O. Haller, G. Kochs, O. Daumke (2011)
Structure of myxovirus resistance protein a reveals intra- and intermolecular domain interactions required for the antiviral function.Immunity, 35 4
N. Che, Song Li, T. Gao, Zhiguo Zhang, Yu-Li Han, Xu-xia Zhang, Yong Sun, Yi Liu, Zhaogang Sun, Jian-yuan Zhang, Wei-cong Ren, M. Tian, Yan Li, Wensheng Li, Jun Cheng, Chuanyou Li (2010)
Identification of a novel IRGM promoter single nucleotide polymorphism associated with tuberculosis.Clinica chimica acta; international journal of clinical chemistry, 411 21-22
Pierre Lapaquette, A. Glasser, A. Huett, R. Xavier, A. Darfeuille‐Michaud (2010)
Crohn's disease‐associated adherent‐invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularlyCellular Microbiology, 12
G. Taylor, C. Feng, A. Sher (2004)
p47 GTPases: regulators of immunity to intracellular pathogensNature Reviews Immunology, 4
Athanasios Theologis, Joseph Ecker, C. Palm, N. Federspiel, S. Kaul, O. White, Jose Alonso, Hootan Alta, R. Araujo, Cheryl Bowman, Shelise Brooks, Eugen Buehler, April Chan, Qimin Chao, Huaming Chen, Rosa Cheuk, Christina Chin, Mike Chung, Lane Conn, Aaron Conway, Andrew Conway, Todd Creasy, Ken Dewar, P. Dunn, Pelin Etgu, T. Feldblyum, J. Feng, B. Fong, C. Fujii, John Gill, Andrew Goldsmith, Brian Haas, Nancy Hansen, Beth Hughes, L. Huizar, J. Hunter, J. Jenkins, Chanda Johnson-Hopson, Shehnaz Khan, E. Khaykin, Christopher Kim, H. Koo, Irina Kremenetskaia, D. Kurtz, A. Kwan, Bao Lam, Stephanie Langin-Hooper, A. Lee, J. Lee, Catherine Lenz, Joycelyn. Li, YaPing Li, Xiaoying Lin, Shirley Liu, Zhaoying Liu, Jason Luros, R. Maiti, Andre Marziali, J. Militscher, Molly Miranda, Michelle Nguyen, W. Nierman, Brian Osborne, G. Pai, J. Peterson, Paul Pham, M. Rizzo, T. Rooney, D. Rowley, H. Sakano, Steven Salzberg, J. Schwartz, Paul Shinn, Audrey Southwick, Hui Sun, Luke Tallon, G. Tambunga, Mitsue Toriumi, Christopher Town, T. Utterback, S. Aken, M. Vaysberg, V. Vysotskaia, M. Walker, Dongying Wu, Guixia Yu, Claire Fraser, J. Venter, Ronald Davis (1999)
Sequence and analysis of chromosome 2 of the plant Arabidopsis thalianaNature, 402
Esmeralda Juárez, C. Carranza, F. Hernández-Sánchez, J. León-Contreras, R. Hernández-Pando, D. Escobedo, M. Torres, E. Sada (2012)
NOD2 enhances the innate response of alveolar macrophages to Mycobacterium tuberculosis in humansEuropean Journal of Immunology, 42
W. Niedelman, Daniel Gold, E. Rosowski, J. Sprokholt, D. Lim, Ailan Arenas, M. Melo, E. Spooner, M. Yaffe, J. Saeij (2012)
The Rhoptry Proteins ROP18 and ROP5 Mediate Toxoplasma gondii Evasion of the Murine, But Not the Human, Interferon-Gamma ResponsePLoS Pathogens, 8
P. Tripal, M. Bauer, E. Naschberger, Thomas Mörtinger, C. Hohenadl, Emmanuelle Cornali, M. Thurau, M. Stürzl (2007)
Unique features of different members of the human guanylate-binding protein family.Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 27 1
C. Intemann, T. Thye, S. Niemann, E. Browne, Margaret Chinbuah, A. Enimil, J. Gyapong, I. Osei, E. Owusu-Dabo, S. Helm, S. Rüsch-Gerdes, R. Horstmann, C. Meyer (2009)
Autophagy Gene Variant IRGM −261T Contributes to Protection from Tuberculosis Caused by Mycobacterium tuberculosis but Not by M. africanum StrainsPLoS Pathogens, 5
Guang Li, Juyong Zhang, Yi Sun, Hua Wang, Yiquan Wang (2009)
The evolutionarily dynamic IFN-inducible GTPase proteins play conserved immune functions in vertebrates and cephalochordates.Molecular biology and evolution, 26 7
F. Kaiser, S. Kaufmann, J. Zerrahn (2004)
IIGP, a member of the IFN inducible and microbial defense mediating 47 kDa GTPase family, interacts with the microtubule binding protein hook3Journal of Cell Science, 117
Munir Al‐Zeer, H. Al-Younes, Peter Braun, J. Zerrahn, T. Meyer (2009)
IFN-γ-Inducible Irga6 Mediates Host Resistance against Chlamydia trachomatis via AutophagyPLoS ONE, 4
S. Ferguson, P. Camilli (2012)
Dynamin, a membrane-remodelling GTPaseNature Reviews Molecular Cell Biology, 13
Yanlin Zhao, D. Ferguson, Douglas Wilson, J. Howard, L. Sibley, G. Yap (2009)
Virulent Toxoplasma gondii Evade Immunity-Related GTPase-Mediated Parasite Vacuole Disruption within Primed Macrophages1The Journal of Immunology, 182
M. Fleckenstein, M. Reese, S. Könen-Waisman, J. Boothroyd, J. Howard, T. Steinfeldt (2012)
A Toxoplasma gondii Pseudokinase Inhibits Host IRG Resistance ProteinsPLoS Biology, 10
Takeshi Matsuzawa, B. Kim, A. Shenoy, S. Kamitani, M. Miyake, J. MacMicking (2012)
IFN-γ Elicits Macrophage Autophagy via the p38 MAPK Signaling PathwayThe Journal of Immunology, 189
Y. Shotland, H. Krämer, E. Groisman (2003)
The Salmonella SpiC protein targets the mammalian Hook3 protein function to alter cellular traffickingMolecular Microbiology, 49
Colicelli (2004)
RE13Sci. STKE, 2004
B. Kim, A. Shenoy, Pradeep Kumar, R. Das, S. Tiwari, J. MacMicking (2011)
A Family of IFN-γ–Inducible 65-kD GTPases Protects Against Bacterial InfectionScience, 332
B. Khor, A. Gardet, R. Xavier (2011)
Genetics and pathogenesis of inflammatory bowel diseaseNature, 474
P. Brest, Pierre Lapaquette, Mouloud Souidi, K. Lebrigand, Annabelle Cesaro, V. Vouret-Craviari, B. Mari, P. Barbry, J. Mosnier, X. Hébuterne, A. Harel-Bellan, B. Mograbi, A. Darfeuille‐Michaud, P. Hofman (2011)
A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's diseaseNature Genetics, 43
Song Gao, A. Malsburg, Susann Paeschke, J. Behlke, O. Haller, G. Kochs, O. Daumke (2010)
Structural basis of oligomerization in the stalk region of dynamin-like MxANature, 465
C. Kuijl, J. Neefjes (2009)
New insight into the everlasting host-pathogen arms raceNature Immunology, 10
Julia Hunn, Stephanie Koenen-Waisman, Natasa Papic, Nina Schroeder, N. Pawlowski, R. Lange, F. Kaiser, J. Zerrahn, Sascha Martens, J. Howard (2008)
Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondiiThe EMBO Journal, 27
I. Bernstein-Hanley, J. Coers, Zarine Balsara, G. Taylor, M. Starnbach, W. Dietrich (2006)
The p47 GTPases Igtp and Irgb10 map to the Chlamydia trachomatis susceptibility locus Ctrq-3 and mediate cellular resistance in miceProceedings of the National Academy of Sciences, 103
Agnidipta Ghosh, Revathy Uthaiah, J. Howard, C. Herrmann, E. Wolf (2004)
Crystal structure of IIGP1: a paradigm for interferon-inducible p47 resistance GTPases.Molecular cell, 15 5
Pardis Sabeti, S. Schaffner, B. Fry, J. Lohmueller, P. Varilly, O. Shamovsky, A. Palma, T. Mikkelsen, D. Altshuler, E. Lander (2006)
Positive Natural Selection in the Human LineageScience, 312
Illya Tietzel, C. El-Haibi, R. Carabeo (2009)
Human Guanylate Binding Proteins Potentiate the Anti-Chlamydia Effects of Interferon-γPLoS ONE, 4
Sudha Singh, Alexander Davis, G. Taylor, V. Deretic (2006)
Human IRGM Induces Autophagy to Eliminate Intracellular MycobacteriaScience, 313
N. Craddock, M. Hurles, Niall Cardin, R. Pearson, V. Plagnol, S. Robson, Damjan Vukcevic, Chris Barnes, D. Conrad, E. Giannoulatou, Chris Holmes, J. Marchini, K. Stirrups, M. Tobin, L. Wain, C. Yau, J. Aerts, T. Ahmad, T. Andrews, Hazel Arbury, A. Attwood, A. Auton, S. Ball, A. Balmforth, J. Barrett, I. Barroso, A. Barton, A. Bennett, S. Bhaskar, K. Błaszczyk, J. Bowes, O. Brand, P. Braund, F. Bredin, G. Breen, Morris Brown, I. Bruce, J. Bull, O. Burren, J. Burton, Jake Byrnes, S. Caesar, C. Clee, A. Coffey, J. Connell, J. Cooper, A. Dominiczak, K. Downes, H. Drummond, D. Dudakia, A. Dunham, Bernadette Ebbs, D. Eccles, S. Edkins, C. Edwards, Anna Elliot, P. Emery, David Evans, G. Evans, S. Eyre, A. Farmer, I. Ferrier, L. Feuk, Tomas Fitzgerald, E. Flynn, A. Forbes, L. Forty, J. Franklyn, R. Freathy, P. Gibbs, Paul Gilbert, O. Gokumen, K. Gordon-Smith, Emma Gray, E. Green, C. Groves, D. Grozeva, R. Gwilliam, A. Hall, Naomi Hammond, Matthew Hardy, Pille Harrison, N. Hassanali, H. Hebaishi, Sarah Hines, A. Hinks, G. Hitman, L. Hocking, E. Howard, Philip Howard, J. Howson, D. Hughes, S. Hunt, J. Isaacs, Mahim Jain, D. Jewell, T. Johnson, J. Jolley, I. Jones, L. Jones, G. Kirov, C. Langford, H. Lango-Allen, G. Lathrop, James Lee, Kate Lee, C. Lees, Kevin Lewis, C. Lindgren, Meeta Maisuria-Armer, J. Maller, J. Mansfield, Paul Martin, D. Massey, W. McArdle, P. McGuffin, K. McLay, A. Mentzer, M. Mimmack, A. Morgan, A. Morris, C. Mowat, S. Myers, W. Newman, E. Nimmo, M. O’Donovan, Abiodun Onipinla, Ifejinelo Onyiah, Nigel Ovington, M. Owen, Kimmo Palin, K. Parnell, D. Pernet, J. Perry, A. Phillips, D. Pinto, N. Prescott, I. Prokopenko, M. Quail, S. Rafelt, N. Rayner, R. Redon, D. Reid, Renwick, S. Ring, N. Robertson, E. Russell, D. Clair, J. Sambrook, J. Sanderson, Helen Schuilenburg, C. Scott, R. Scott, S. Seal, S. Shaw-Hawkins, B. Shields, M. Simmonds, D. Smyth, Elilan Somaskantharajah, Katarina Spanova, S. Steer, J. Stephens, H. Stevens, M. Stone, Z. Su, D. Symmons, J. Thompson, W. Thomson, M. Travers, C. Turnbull, A. Valsesia, M. Walker, N. Walker, C. Wallace, M. Warren-Perry, N. Watkins, J. Webster, M. Weedon, A. Wilson, Matt Woodburn, B. Wordsworth, A. Young, E. Zeggini, N. Carter, T. Frayling, Charles Lee, G. McVean, P. Munroe, A. Palotie, S. Sawcer, S. Scherer, D. Strachan, C. Tyler-Smith, M. Brown, P. Burton, M. Caulfield, Alastair Compston, M. Farrall, S. Gough, A. Hall, A. Hattersley, A. Hill, C. Mathew, M. Pembrey, J. Satsangi, M. Stratton, Jane Worthington, P. Deloukas, A. Duncanson, D. Kwiatkowski, M. McCarthy, W. Ouwehand, M. Parkes, N. Rahman, J. Todd, N. Samani, P. Donnelly (2010)
Genome-wide association study of copy number variation in 16,000 cases of eight common diseases and 3,000 shared controls
S. Tiwari, Han-Pil Choi, Takeshi Matsuzawa, M. Pypaert, J. MacMicking (2009)
Targeting of the GTPase Irgm1 to the phagosomal membrane via PtdIns(3,4)P2 and PtdIns(3,4,5)P3 promotes immunity to mycobacteriaNature Immunology, 10
O. Haller, G. Kochs (2011)
Human MxA protein: an interferon-induced dynamin-like GTPase with broad antiviral activity.Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 31 1
G. Taylor, M. Jeffers, D. Largaespada, N. Jenkins, N. Copeland, G. Woude (1996)
Identification of a Novel GTPase, the Inducibly Expressed GTPase, That Accumulates in Response to Interferon γ*The Journal of Biological Chemistry, 271
T. Steinfeldt, Stephanie Nen-Waisman, Lan Tong, N. Pawlowski, Tobias Lamkemeyer, L. Sibley, Julia Hunn, J. Howard, G. Ward (2010)
Phosphorylation of Mouse Immunity-Related GTPase (IRG) Resistance Proteins Is an Evasion Strategy for Virulent Toxoplasma gondiiPLoS Biology, 8
R. Medzhitov, David Schneider, M. Soares (2012)
Disease Tolerance as a Defense StrategyScience, 335
I. Miyairi, V. Tatireddigari, O. Mahdi, Lorne Rose, R. Belland, Luan-mei Lu, Robert Williams, G. Byrne (2007)
The p47 GTPases Iigp2 and Irgb10 Regulate Innate Immunity and Inflammation to Murine Chlamydia psittaci Infection1The Journal of Immunology, 179
Zijiang Zhao, B. Fux, Megan Goodwin, I. Dunay, D. Strong, Brian Miller, K. Cadwell, Mônica Delgado, Marisa Ponpuak, K. Green, R. Schmidt, N. Mizushima, V. Deretic, L. Sibley, H. Virgin (2008)
Autophagosome-Independent Essential Function for the Autophagy Protein Atg5 in Cellular Immunity to Intracellular PathogensCell Host & Microbe, 4
Sascha Martens, I. Parvanova, J. Zerrahn, G. Griffiths, Gudrun Schell, G. Reichmann, J. Howard (2005)
Disruption of Toxoplasma gondii Parasitophorous Vacuoles by the Mouse p47-Resistance GTPasesPLoS Pathogens, 1
Cell Host & Microbe – Unpaywall
Published: Oct 1, 2012
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