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Hyperlipidaemia in primary care — a randomized controlled trial on treatment information in Sweden: Design and methodology

Hyperlipidaemia in primary care — a randomized controlled trial on treatment information in... This paper presents the design and methodology of a large scale information dissemination experiment in Swedish primary care, executed in collaboration with policy makers and information pharmacists, and focused on the effects of an information package presented verbally by community pharmacists, with regard to the doctors' knowledge, attitudes, perceptions and practice in the treatment of hyperlipidaemia. The main study group comprised 570 doctors, belonging to 67 matched pairs of community health centres (CHCs), randomization being performed at group (i.e. CHC) level to minimize ethical and practical problems. The information derived from national expert guidelines, and was presented at four group sessions during six months at each of the intervention group CHCs, 79% of which fulfilled this requirement. Baseline and outcome data were collected from prescriptions, serum cholesterol test results, questionnaires on attitudes and case‐management evaluation. Moreover, interviews and field observations were conducted in a subsample of CHCs. We demonstrate ways of overcoming methodological problems such as minimizing the Hawthorne effect by introducing an extra, control group and the expectancy effect by not obtaining informed consent until the end of the study period. There was a non‐respondence rate of 21% which is similar to results in trials on drug efficacy. The acceptance rate vis‐à‐vis the study evaluation was 86%, but might have been higher had the ethical and methodological aspects special to experiments with treatment information been better understood. The information model has afterwards been used in Sweden for information campaigns focused on therapeutic guidelines. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Pharmacoepidemiology and Drug Safety Wiley

Hyperlipidaemia in primary care — a randomized controlled trial on treatment information in Sweden: Design and methodology

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References (62)

Publisher
Wiley
Copyright
Copyright © 1995 John Wiley & Sons, Ltd
ISSN
1053-8569
eISSN
1099-1557
DOI
10.1002/pds.2630040203
Publisher site
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Abstract

This paper presents the design and methodology of a large scale information dissemination experiment in Swedish primary care, executed in collaboration with policy makers and information pharmacists, and focused on the effects of an information package presented verbally by community pharmacists, with regard to the doctors' knowledge, attitudes, perceptions and practice in the treatment of hyperlipidaemia. The main study group comprised 570 doctors, belonging to 67 matched pairs of community health centres (CHCs), randomization being performed at group (i.e. CHC) level to minimize ethical and practical problems. The information derived from national expert guidelines, and was presented at four group sessions during six months at each of the intervention group CHCs, 79% of which fulfilled this requirement. Baseline and outcome data were collected from prescriptions, serum cholesterol test results, questionnaires on attitudes and case‐management evaluation. Moreover, interviews and field observations were conducted in a subsample of CHCs. We demonstrate ways of overcoming methodological problems such as minimizing the Hawthorne effect by introducing an extra, control group and the expectancy effect by not obtaining informed consent until the end of the study period. There was a non‐respondence rate of 21% which is similar to results in trials on drug efficacy. The acceptance rate vis‐à‐vis the study evaluation was 86%, but might have been higher had the ethical and methodological aspects special to experiments with treatment information been better understood. The information model has afterwards been used in Sweden for information campaigns focused on therapeutic guidelines.

Journal

Pharmacoepidemiology and Drug Safety – Wiley

Published: Mar 1, 1995

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