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Fetal and Pediatric Pathology, 26:61–62, 2007 Copyright # Informa Healthcare ISSN: 1551-3815 print/1551-3823 online DOI: 10.1080/15513810701394736 BOOK REVIEW Developmental Origins of Health and Disease, Peter Gluckman and Mark Hanson, editors Cambridge: Cambridge University Press, 521 pages, $150. This book contains 37 chapters devoted to the developmental and environ- mental origin of health and disease. It includes an overview, epidemiology, developmental origins, periconceptional and embryonic influences, epi- genetic mechanisms, mitochondrial component of developmental pro- gramming, environmental chemicals, maternal nutrition and fetal growth and development, placental mechanisms, control of fetal metabolism, lipid metabolism, prenatal hypoxia, endocrine factors, development of obesity, programming of the cardiovascular system, atherogenesis, renal function, fluid and electrolyte homeostasis, lung structure and function, develop- mental origins of asthma and related allergic disorders, the origins of neurological disorders, musculoskeletal system, skeletal development, the early origins of cancer, the developmental environments and its implica- tions for aging and life span, and finally public health perspectives, the implications for developing countries, ethical and social considerations, and past obstacles and future promise. This unique publication presents the first definitive account of how subtle influences on the fetus and during early life have such profound consequences for adult health and diseases. The scientific
Fetal & Pediatric Pathology – Taylor & Francis
Published: Jan 1, 2007
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