Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 7-Day Trial for You or Your Team.

Learn More →

Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression

Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family... Downloaded from genesdev.cshlp.org on November 30, 2021 - Published by Cold Spring Harbor Laboratory Press Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression 1 1,6 2,6 1 3,4 Don L. Gibbons, Wei Lin, Chad J. Creighton, Zain H. Rizvi, Philip A. Gregory, 3,4 1 5 2 Gregory J. Goodall, Nishan Thilaganathan, Liqin Du, Yiqun Zhang, 5 1,7 Alexander Pertsemlidis, and Jonathan M. Kurie Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, 2 3 Texas 77030, USA; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas 77030, USA; Division of Human Immunology, Centre for Cancer Biology, Hanson Institute, Adelaide, SA 5000 Australia; Discipline of Medicine, The University of Adelaide, Adelaide, SA 5005 Australia; Eugene McDermott Center for Human Growth and Development, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA Metastatic disease is a primary cause of cancer-related death, and factors governing tumor cell metastasis have not been fully elucidated. Here, we address this question by using tumor cell lines derived from mice that develop metastatic lung adenocarcinoma owing to expression of mutant K-ras and p53. Despite having widespread somatic genetic alterations, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Genes & Development Unpaywall

Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression

Download PDF
13 pages

Loading next page...
 
/lp/unpaywall/contextual-extracellular-cues-promote-tumor-cell-emt-and-metastasis-by-j2AKfP4OT4

References

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

Publisher
Unpaywall
ISSN
0890-9369
DOI
10.1101/gad.1820209
Publisher site
See Article on Publisher Site

Abstract

Downloaded from genesdev.cshlp.org on November 30, 2021 - Published by Cold Spring Harbor Laboratory Press Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression 1 1,6 2,6 1 3,4 Don L. Gibbons, Wei Lin, Chad J. Creighton, Zain H. Rizvi, Philip A. Gregory, 3,4 1 5 2 Gregory J. Goodall, Nishan Thilaganathan, Liqin Du, Yiqun Zhang, 5 1,7 Alexander Pertsemlidis, and Jonathan M. Kurie Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, 2 3 Texas 77030, USA; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas 77030, USA; Division of Human Immunology, Centre for Cancer Biology, Hanson Institute, Adelaide, SA 5000 Australia; Discipline of Medicine, The University of Adelaide, Adelaide, SA 5005 Australia; Eugene McDermott Center for Human Growth and Development, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA Metastatic disease is a primary cause of cancer-related death, and factors governing tumor cell metastasis have not been fully elucidated. Here, we address this question by using tumor cell lines derived from mice that develop metastatic lung adenocarcinoma owing to expression of mutant K-ras and p53. Despite having widespread somatic genetic alterations,

Journal

Genes & Development – Unpaywall

Published: Sep 15, 2009

There are no references for this article.