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DERMATITIS MEDICAMENTOSA: A TEN‐YEAR STUDY

DERMATITIS MEDICAMENTOSA: A TEN‐YEAR STUDY Hedvig Torok, M.D. The development and usage of many new drugs with profound effects on the body is a feature of modern medical science. These drugs which benefit mankind, however, are often the cause of undesirable side effects. Thus dermatoses caused by the use of powerful drugs have become a topic for study within the science of dermatology. The nomenclature describing these conditions varies widely. In French usage exanthema caused by drugs means the patient's intolerance to the drug,' Jadassohn"^ and Mayer^ use toxicoderma to distinguish skin conditions with allergic origin, rather than toxic origin, Perutz" combines the two usages and separates them according to means of contact with the irritant: either by ingestion or by skin contact. Miescher^ regards as drugexanthema flushing and edema of skin and mucous membranes caused by the drug as an allergen rather than as toxic agent. The cases studied at our institution involving skin have been divided into (1) exanthemata caused by drugs ingested and (2) contact dermatitis caused by skin contact with drugs. The majority of the causes were allergic, but in some patients toxic effects were also apparent. It is well known that the same drug can produce a gamut http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png International Journal of Dermatology Wiley

DERMATITIS MEDICAMENTOSA: A TEN‐YEAR STUDY

International Journal of Dermatology , Volume 8 (2‐4) – Apr 1, 1969

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References (18)

Publisher
Wiley
Copyright
Copyright © 1969 Wiley Subscription Services, Inc., A Wiley Company
ISSN
0011-9059
eISSN
1365-4632
DOI
10.1111/j.1365-4362.1969.tb05332.x
Publisher site
See Article on Publisher Site

Abstract

Hedvig Torok, M.D. The development and usage of many new drugs with profound effects on the body is a feature of modern medical science. These drugs which benefit mankind, however, are often the cause of undesirable side effects. Thus dermatoses caused by the use of powerful drugs have become a topic for study within the science of dermatology. The nomenclature describing these conditions varies widely. In French usage exanthema caused by drugs means the patient's intolerance to the drug,' Jadassohn"^ and Mayer^ use toxicoderma to distinguish skin conditions with allergic origin, rather than toxic origin, Perutz" combines the two usages and separates them according to means of contact with the irritant: either by ingestion or by skin contact. Miescher^ regards as drugexanthema flushing and edema of skin and mucous membranes caused by the drug as an allergen rather than as toxic agent. The cases studied at our institution involving skin have been divided into (1) exanthemata caused by drugs ingested and (2) contact dermatitis caused by skin contact with drugs. The majority of the causes were allergic, but in some patients toxic effects were also apparent. It is well known that the same drug can produce a gamut

Journal

International Journal of DermatologyWiley

Published: Apr 1, 1969

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