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THE BRITISH JOURNAL OF DERMATOLOGY AUGUST-SEPTEMBER 1964 R. B. SWEET. Tlymoiitli GoiK'i'a! Hospital. I N the course of the last fifteen years T liavo eneountered eight patients wlio liave had what seems to ho a distinttive and fairly severe ilhiess. It is accom- panied by a skin eruption whieh. although presumably reactive in nature and somewhat resomhling erythema multiforme in appearance and duration, is I believe elinically and histologi( ally distinctive. The four cardinal features, are fever, neutrophil ])olymorphonucloar leueotytosis of the blood, raised painful plaques on the limbs, face and neck and histologically a dense dermal infdtration with mature neutropliil ]>olymorj>hs. No evidence of infection is to be found. Response to corticosteroid drugs is rapid and complete. The object of this paper is to draw a composite picture of the condition and behaviour of these patients and to describe briefly their variations. I hope that thereby others who have seen similar cases may at least Iiave the intellectual satisfaction of heing able to classify them, oven tliougli they will remain as ignorant as ever about their essential nature. ClJNICAI, PiC'TUltE. All eight patients have been women between tlie ages of ^^2 an d 5;"). One or more erythematous
British Journal of Dermatology – Oxford University Press
Published: Aug 1, 1964
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