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Regional Lymphadenectomy Is Indicated in the Surgical Treatment of Pancreatic Neuroendocrine Tumors (PNETs)

Regional Lymphadenectomy Is Indicated in the Surgical Treatment of Pancreatic Neuroendocrine... FEATURE Regional Lymphadenectomy Is Indicated in the Surgical Treatment of Pancreatic Neuroendocrine Tumors (PNETs) ∗ ∗ ∗ Yassar M. Hashim, MD, Kathryn M. Trinkaus, PhD,† David C. Linehan, MD, Steven S. Strasberg, MD, ∗ ∗ Ryan C. Fields, MD, Dengfeng Cao, MD, PhD,‡ and William G. Hawkins, MD clinical outcomes of PNETs vary greatly, and although the majority Objective: To explore the prognostic importance and preoperative predictors are relatively benign, slow growing, and noninfiltrative, a subset is of lymph node metastasis in an effort to guide surgical decision making in aggressive, rapidly metastasizing, and locally invasive. PNETs can patients with pancreatic neuroendocrine tumors (PNETs). also be divided into functional and nonfunctional on the basis of Background: PNETs are uncommon, and the natural history of the disease hypersecretion of biologically active hormones, resulting in clinical is not well described. As a result, there remains controversy regarding the syndromes. The natural history of PNETs is consequently highly optimal management of regional lymph nodes during resection of the primary variable, with the majority having a more favorable outcome and tumor. longer overall survival (OS) after surgical resection than pancreatic Methods: A retrospective review of a prospectively maintained database of 5 6 adenocarcinoma. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Surgery Wolters Kluwer Health

Regional Lymphadenectomy Is Indicated in the Surgical Treatment of Pancreatic Neuroendocrine Tumors (PNETs)

Hawkins, William G.
Annals of Surgery , Volume 259 (2) – Feb 1, 2014
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References (40)

Copyright
© 2013 by Lippincott Williams & Wilkins
ISSN
0003-4932
eISSN
1528-1140
DOI
10.1097/SLA.0000000000000348
pmid
24253141
Publisher site
See Article on Publisher Site

Abstract

FEATURE Regional Lymphadenectomy Is Indicated in the Surgical Treatment of Pancreatic Neuroendocrine Tumors (PNETs) ∗ ∗ ∗ Yassar M. Hashim, MD, Kathryn M. Trinkaus, PhD,† David C. Linehan, MD, Steven S. Strasberg, MD, ∗ ∗ Ryan C. Fields, MD, Dengfeng Cao, MD, PhD,‡ and William G. Hawkins, MD clinical outcomes of PNETs vary greatly, and although the majority Objective: To explore the prognostic importance and preoperative predictors are relatively benign, slow growing, and noninfiltrative, a subset is of lymph node metastasis in an effort to guide surgical decision making in aggressive, rapidly metastasizing, and locally invasive. PNETs can patients with pancreatic neuroendocrine tumors (PNETs). also be divided into functional and nonfunctional on the basis of Background: PNETs are uncommon, and the natural history of the disease hypersecretion of biologically active hormones, resulting in clinical is not well described. As a result, there remains controversy regarding the syndromes. The natural history of PNETs is consequently highly optimal management of regional lymph nodes during resection of the primary variable, with the majority having a more favorable outcome and tumor. longer overall survival (OS) after surgical resection than pancreatic Methods: A retrospective review of a prospectively maintained database of 5 6 adenocarcinoma.

Journal

Annals of Surgery – Wolters Kluwer Health

Published: Feb 1, 2014

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