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Modification of the action of pentagastrin on acid secretion by botulinum toxin

Modification of the action of pentagastrin on acid secretion by botulinum toxin I.v. botulinum toxin after 60–90 min abolished the dose-response relationship between pentagastrin and gastric acid secretion in anesthetized rats and guinea-pigs. The toxin reduced but did not abolish the acid stimulatory effect of histamine. As expected, the acid response to vagal stimulation was abolished and that to methacholine in rats was unaltered by the toxin. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Cellular and Molecular Life Sciences Springer Journals

Modification of the action of pentagastrin on acid secretion by botulinum toxin

Kondo, T.; Magee, D.
Cellular and Molecular Life Sciences , Volume 33 (6) – Jun 30, 2005
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References (5)

Publisher
Springer Journals
Copyright
Copyright © 1977 by Birkhäuser Verlag
Subject
Life Sciences; Cell Biology; Biomedicine, general; Life Sciences, general; Biochemistry, general
ISSN
1420-682X
eISSN
1420-9071
DOI
10.1007/BF01944169
Publisher site
See Article on Publisher Site

Abstract

I.v. botulinum toxin after 60–90 min abolished the dose-response relationship between pentagastrin and gastric acid secretion in anesthetized rats and guinea-pigs. The toxin reduced but did not abolish the acid stimulatory effect of histamine. As expected, the acid response to vagal stimulation was abolished and that to methacholine in rats was unaltered by the toxin.

Journal

Cellular and Molecular Life Sciences – Springer Journals

Published: Jun 30, 2005

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