Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 7-Day Trial for You or Your Team.

Learn More →

The ins and outs of signalling

The ins and outs of signalling The study of how cells communicate impinges on all aspects of biology, from development to disease. At first glance it's a horrendously complicated business, but some simple themes are emerging. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nature Springer Journals

The ins and outs of signalling

Downward, Julian
Nature , Volume 411 (6839) – Jun 14, 2001
Download PDF
4 pages

Loading next page...
 
/lp/springer-journals/the-ins-and-outs-of-signalling-c73Zcl3hGK

References (35)

  • J. Shields, Kevin Pruitt, Aidan McFall, A. Shaub, C. Der (2000)

    Understanding Ras: 'it ain't over 'til it's over'.

    Trends in cell biology, 10 4

  • (1998)

    Trans. R. Soc. Lond. B

  • D. Christophe, C. Christophe-Hobertus, B. Pichon (2000)

    Nuclear targeting of proteins: how many different signals?

    Cellular signalling, 12 5

  • S. Oliver, M. Winson, D. Kell, F. Baganz (1998)

    Systematic functional analysis of the yeast genome.

    Trends in biotechnology, 16 9

  • G. Plowman, S. Sudarsanam, J. Bingham, D. Whyte, T. Hunter (1999)

    The protein kinases of Caenorhabditis elegans: a model for signal transduction in multicellular organisms.

    Proceedings of the National Academy of Sciences of the United States of America, 96 24

  • A. Walhout, M. Vidal (2001)

    Protein interaction maps for model organisms

    Nature Reviews Molecular Cell Biology, 2

  • (1997)

    Bioessays

  • R. Kornberg (1999)

    Eukaryotic transcriptional control.

    Trends in cell biology, 9 12

  • (2001)

    Nature

  • J. Massagué, Ye-Guang Chen (2000)

    Controlling TGF-β signaling

    Genes & Development

  • (2000)

    Trends Cell Biol

  • D. Endy, R. Brent (2001)

    Modelling cellular behaviour

    Nature, 409

  • T. Pawson, John Scott (1997)

    Signaling through scaffold, anchoring, and adaptor proteins.

    Science, 278 5346

  • (1999)

    Proc. Natl Acad. Sci. USA 96

  • T. Pawson (1995)

    Protein modules and signalling networks

    Nature, 373

  • D. Schlaepfer, T. Hunter (1998)

    Integrin signalling and tyrosine phosphorylation: just the FAKs?

    Trends in cell biology, 8 4

  • (1998)

    Trends Biochem. Sci

  • S. Datta, A. Brunet, M. Greenberg (1999)

    Cellular survival: a play in three Akts.

    Genes & development, 13 22

  • Almut Schulze, Julian Downward (2000)

    Analysis of gene expression by microarrays : cell biologist ’ s gold mine or minefield ?

  • (2000)

    J. J. Cell Sci

  • A. Whitmarsh, R. Davis (1998)

    Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals.

    Trends in biochemical sciences, 23 12

  • E. Lander, L. Linton, B. Birren, C. Nusbaum, M. Zody, J. Baldwin, K. Devon, K. Dewar, M. Doyle, W. Fitzhugh, R. Funke, D. Gage, K. Harris, A. Heaford, J. Howland, L. Kann, J. Lehoczky, R. Levine, P. McEwan, K. McKernan, J. Meldrim, J. Mesirov, C. Miranda, W. Morris, J. Naylor, C. Raymond, M. Rosetti, R. Santos, A. Sheridan, C. Sougnez, Y. Stange-Thomann, N. Stojanovic, A. Subramanian, D. Wyman, J. Rogers, J. Sulston, R. Ainscough, S. Beck, D. Bentley, J. Burton, C. Clee, N. Carter, A. Coulson, R. Deadman, P. Deloukas, A. Dunham, I. Dunham, R. Durbin, L. French, D. Grafham, S. Gregory, T. Hubbard, S. Humphray, A. Hunt, M. Jones, C. Lloyd, A. McMurray, L. Matthews, S. Mercer, S. Milne, J. Mullikin, A. Mungall, R. Plumb, M. Ross, R. Shownkeen, S. Sims, R. Waterston, R. Wilson, L. Hillier, J. McPherson, M. Marra, E. Mardis, L. Fulton, A. Chinwalla, K. Pepin, W. Gish, S. Chissoe, M. Wendl, K. Delehaunty, T. Miner, A. Delehaunty, J. Kramer, L. Cook, R. Fulton, D. Johnson, P. Minx, S. Clifton, T. Hawkins, E. Branscomb, P. Predki, P. Richardson, S. Wenning, T. Slezak, N. Doggett, J. Cheng, A. Olsen, S. Lucas, C. Elkin, E. Uberbacher, M. Frazier, R. Gibbs, D. Muzny, S. Scherer, J. Bouck, E. Sodergren, K. Worley, C. Rives, J. Gorrell, M. Metzker, S. Naylor, R. Kucherlapati, D. Nelson, G. Weinstock, Y. Sakaki, A. Fujiyama, M. Hattori, T. Yada, A. Toyoda, T. Itoh, C. Kawagoe, H. Watanabe, Y. Totoki, T. Taylor, J. Weissenbach, R. Heilig, W. Saurin, F. Artiguenave, P. Brottier, T. Bruls, É. Pelletier, C. Robert, P. Wincker, D. Smith, L. Doucette-Stamm, M. Rubenfield, K. Weinstock, H. Lee, J. Dubois, A. Rosenthal, M. Platzer, G. Nyakatura, S. Taudien, A. Rump, H. Yang, J. Yu, J. Wang, G. Huang, J. Gu, L. Hood, L. Rowen, A. Madan, S. Qin, R. Davis, N. Federspiel, A. Abola, M. Proctor, R. Myers, J. Schmutz, M. Dickson, J. Grimwood, D. Cox, M. Olson, R. Kaul, N. Shimizu, K. Kawasaki, S. Minoshima, G. Evans, M. Athanasiou, R. Schultz, B. Roe, F. Chen, H. Pan, J. Ramser, H. Lehrach, R. Reinhardt, W. McCombie, M. Bastide, N. Dedhia, H. Blöcker, K. Hornischer, G. Nordsiek, R. Agarwala, L. Aravind, J. Bailey, A. Bateman, S. Batzoglou, E. Birney, P. Bork, D. Brown, C. Burge, L. Cerutti, H. Chen, D. Church, M. Clamp, R. Copley, T. Doerks, S. Eddy, E. Eichler, T. Furey, J. Galagan, J. Gilbert, C. Harmon, Y. Hayashizaki, D. Haussler, H. Hermjakob, K. Hokamp, W. Jang, L. Johnson, T. Jones, S. Kasif, A. Kaspryzk, S. Kennedy, W. Kent, P. Kitts, E. Koonin, I. Korf, D. Kulp, D. Lancet, Gwênlyn Glusman, T. Lowe, A. McLysaght, T. Mikkelsen, J. Moran, N. Mulder, V. Pollara, C. Ponting, G. Schuler, J. Schultz, G. Slater, A. Smit, E. Stupka, J. Szustakowki, D. Thierry-Mieg, J. Thierry-Mieg, L. Wagner, J. Wallis, R. Wheeler, A. Williams, Y. Wolf, K. Wolfe, S. Yang, R. Yeh, F. Collins, M. Guyer, J. Peterson, A. Felsenfeld, K. Wetterstrand, A. Patrinos, M. Morgan, P. Jong, J. Catanese, K. Osoegawa, H. Shizuya, S. Choi, Y. Chen, Vacslav Glukhov (2001)

    Initial sequencing and analysis of the human genome.

    Nature, 409 6822

  • J. Cortes, S. O'brien (1994)

    Chronic myelogenous leukemia.

    Current opinion in oncology, 6 1

  • J. Daniel, A. Reynolds (1997)

    Tyrosine phosphorylation and cadherin/catenin function

    BioEssays, 19

  • (2001)

    Curr. Opin. Oncol

  • D. Withers, M. White (2000)

    Perspective: The Insulin Signaling System-A Common Link in the Pathogenesis of Type 2 Diabetes.

    Endocrinology, 141 6

  • C. Marshall (1995)

    Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation

    Cell, 80

  • (2001)

    International Human Genome Sequencing Consortium Nature 409

  • J. Venter, M. Adams, E. Myers, Peter Li, R. Mural, G. Sutton, Hamilton Smith, M. Yandell, C. Evans, R. Holt, J. Gocayne, P. Amanatides, R. Ballew, D. Huson, J. Wortman, Qing Zhang, C. Kodira, Xiangqun Zheng, Lin Chen, M. Skupski, G. Subramanian, P. Thomas, Jinghui Zhang, George Miklos, C. Nelson, S. Broder, A. Clark, Joe Nadeau, V. McKusick, N. Zinder, A. Levine, R. Roberts, M. Simon, C. Slayman, M. Hunkapiller, Randall Bolanos, A. Delcher, I. Dew, D. Fasulo, M. Flanigan, L. Florea, A. Halpern, S. Hannenhalli, S. Kravitz, S. Levy, C. Mobarry, K. Reinert, K. Remington, J. Abu-Threideh, E. Beasley, Kendra Biddick, Vivien Bonazzi, R. Brandon, M. Cargill, Ishwar Chandramouliswaran, R. Charlab, Kabir Chaturvedi, Z. Deng, V. Francesco, P. Dunn, K. Eilbeck, C. Evangelista, A. Gabrielian, W. Gan, Wangmao Ge, F. Gong, Z. Gu, P. Guan, T. Heiman, Maureen Higgins, Rui-Ru Ji, Zhaoxi Ke, K. Ketchum, Z. Lai, Yi-Ting Lei, Zhenya Li, Jiayin Li, Yong Liang, Xiaoying Lin, Fu Lu, G. Merkulov, N. Milshina, Helen Moore, Ashwinikumar Naik, Vaibhav Narayan, Beena Neelam, D. Nusskern, D. Rusch, S. Salzberg, Wei Shao, B. Shue, Jingtao Sun, Zhen Wang, Aihui Wang, Xin Wang, Jian Wang, M. Wei, R. Wides, Chunlin Xiao, Chunhua Yan, Alison Yao, J. Ye, M. Zhan, Weiqing Zhang, Hongyu Zhang, Q. Zhao, Lian-rong Zheng, F. Zhong, W. Zhong, Shiaoping Zhu, Shaying Zhao, Dennis Gilbert, Suzanna Baumhueter, G. Spier, Christine Carter, A. Cravchik, T. Woodage, Feroze Ali, H. An, A. Awe, D. Baldwin, H. Baden, Mary Barnstead, I. Barrow, K. Beeson, D. Busam, Amy Carver, A. Center, Ming-Ming Cheng, Liz Curry, S. Danaher, L. Davenport, Raymond Desilets, S. Dietz, K. Dodson, L. Doup, S. Ferriera, Neha Garg, Andres Gluecksmann, Britney Hart, Jason Haynes, C. Haynes, C. Heiner, S. Hladun, D. Hostin, J. Houck, T. Howland, C. Ibegwam, Jeffery Johnson, F. Kalush, Lesley Kline, Shashi Koduru, Amy Love, Felecia Mann, D. May, Steven McCawley, T. McIntosh, Ivy McMullen, M. Moy, Linda Moy, B. Murphy, K. Nelson, C. Pfannkoch, Eric Pratts, V. Puri, Hina-Ur-Razaq Qureshi, Matt Reardon, Robert Rodriguez, Y. Rogers, Deanna Romblad, Bob Ruhfel, Richard Scott, Cynthia Sitter, Michelle Smallwood, Erin Stewart, R. Strong, Ellen Suh, R. Thomas, Ni Tint, S. Tse, C. Vech, Gary Wang, J. Wetter, Sherita Williams, Monica Williams, Sandra Windsor, E. Winn-Deen, Keriellen Wolfe, J. Zaveri, K. Zaveri, J. Abril, R. Guigó, M. Campbell, K. Sjolander, Brian Karlak, A. Kejariwal, H. Mi, B. Lazareva, Thomas Hatton, A. Narechania, Karen Diemer, A. Muruganujan, Nan Guo, Shinji Sato, V. Bafna, S. Istrail, R. Lippert, R. Schwartz, B. Walenz, Shibu Yooseph, D. Allen, A. Basu, J. Baxendale, L. Blick, Marcelo Caminha, John Carnes-Stine, Parris Caulk, Yen-Hui Chiang, My Coyne, C. Dahlke, A. Mays, M. Dombroski, Michael Donnelly, Dale Ely, Shiva Esparham, C. Fosler, Harold Gire, S. Glanowski, K. Glasser, A. Glodek, M. Gorokhov, K. Graham, Barry Gropman, M. Harris, Jeremy Heil, Scott Henderson, Jeffrey Hoover, D. Jennings, Catherine Jordan, J. Jordan, John Kasha, Leonid Kagan, C. Kraft, A. Levitsky, Mark Lewis, Xiangjun Liu, John Lopez, Daniel Ma, W. Majoros, J. McDaniel, Sean Murphy, Matthew Newman, Trung Nguyen, N. Nguyen, Marc Nodell, S. Pan, Jim Peck, Marshall Peterson, William Rowe, Robert Sanders, J. Scott, M. Simpson, Thomas Smith, A. Sprague, Timothy Stockwell, Russell Turner, E. Venter, Mei Wang, M. Wen, David Wu, Mitchell Wu, Ashley Xia, A. Zandieh, Xiaohong Zhu (2001)

    The Sequence of the Human Genome

    Science, 291

  • (2001)

    Science

  • (2000)

    Genes Dev

  • (1998)

    Annu. Rev. Biochem

  • T. Hunter (1998)

    The Croonian Lecture 1997. The phosphorylation of proteins on tyrosine: its role in cell growth and disease.

    Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 353 1368

  • P. Cohen (2000)

    The regulation of protein function by multisite phosphorylation--a 25 year update.

    Trends in biochemical sciences, 25 12

  • (2000)

    Cell Signal

Publisher
Springer Journals
Copyright
Copyright © 2001 by Nature Publishing Group
Subject
Science, Humanities and Social Sciences, multidisciplinary; Science, Humanities and Social Sciences, multidisciplinary; Science, multidisciplinary
ISSN
0028-0836
eISSN
1476-4687
DOI
10.1038/35081138
Publisher site
See Article on Publisher Site

Abstract

The study of how cells communicate impinges on all aspects of biology, from development to disease. At first glance it's a horrendously complicated business, but some simple themes are emerging.

Journal

Nature – Springer Journals

Published: Jun 14, 2001

There are no references for this article.