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Int J Legal Med (2015) 129:85–88 DOI 10.1007/s00414-014-0997-x CASE REPORT Sleep self-intoxication and sleep driving as rare zolpidem-induced complex behaviour Alexander Paulke & Cora Wunder & Stefan W. Toennes Received: 6 February 2014 /Accepted: 16 April 2014 /Published online: 27 April 2014 Springer-Verlag Berlin Heidelberg 2014 Abstract mood changes may indicate a zolpidem-induced Introduction The GABA receptor agonist zolpidem has been somnambulism-like state with sleep-related complex used for treatment of insomnia since years, but special side behaviour. effects have been reported. These side effects were called zolpidem-induced sleep-related complex behaviour. Such . . . complex behaviour is associated with somnambulism and Keywords Zolpidem Somnambulism Self-intoxication includes sleepwalking, sleep eating, sleep conversation and Complex behaviour sleep driving. Case presentation Two cases of zolpidem-induced sleep- related complex behaviour following self-intoxication, sleep driving and amnesia are presented. In both cases, Introduction the subjects reported the voluntary intake of only one zolpidem tablet of 10 mg and amnesia for the time Since more than two decades, the GABA receptor afterwards. Shortly after the onset of the drug’saction, agonist zolpidem has been used for the treatment of both individuals drifted into a somnambulism-like state insomnia. Epidemiological data indicate a lower inci- and toxicological blood
International Journal of Legal Medicine – Springer Journals
Published: Apr 27, 2014
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