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Annexin 1 localisation in tissue eosinophils as detected by electron microscopy

Annexin 1 localisation in tissue eosinophils as detected by electron microscopy Research Communication Mediators of Inflammation, 11, 287– 292 (2002) BACKGROUND: Human and rodent leukocytes express Annexin 1 localisation in tissue high levels of the glucocorticoid-inducible protein annexin 1 (ANXA1) (previously referred to as lipo- eosinophils as detected by electron cortin 1). Neutrophils and monocytes have abundant microscopy ANXA1 levels. Aim: We have investigated, for the first time, ANXA1 ultrastructural expression in rat eosinophils and 1,2 2 compared it with that of extravasated neutrophils. Sonia M. Oliani , Amilcar S. Damazo and Mauro The effect of inflammation (carrageenin peritonitis) 3,CA Perretti was also monitored. Methods: Electron microscopy was used to define the sub-cellular localisation of ANXA1 in rat eosinophils Department of Biology, IBILCE – UNESP, Sa ˜ o Jose ´ and neutrophils extravasated in the mesenteric tis- sue. A pair of antibodies raised against the ANXA1 do Rio Preto, SP, Brazil; Department of Morphology, N-terminus (i.e. able to recognise intact ANXA1, UNIFESP – EPM, Sao ˜ Paulo, SP, Brazil; and The termed LCPS1) or the whole protein (termed LCS3) William Harvey Research Institute, Bart’s and The was used to perform the ultrastructural analysis. London, Queen Mary School of Medicine and Results: The majority of ANXA1 was localised in the Dentistry, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mediators of Inflammation Unpaywall

Annexin 1 localisation in tissue eosinophils as detected by electron microscopy

Oliani, Sonia M.; Damazo, Amilcar S.; Perretti, Mauro
Mediators of Inflammation – Jan 1, 2000
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Unpaywall
ISSN
0962-9351
DOI
10.1080/09629350210000015683
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Abstract

Research Communication Mediators of Inflammation, 11, 287– 292 (2002) BACKGROUND: Human and rodent leukocytes express Annexin 1 localisation in tissue high levels of the glucocorticoid-inducible protein annexin 1 (ANXA1) (previously referred to as lipo- eosinophils as detected by electron cortin 1). Neutrophils and monocytes have abundant microscopy ANXA1 levels. Aim: We have investigated, for the first time, ANXA1 ultrastructural expression in rat eosinophils and 1,2 2 compared it with that of extravasated neutrophils. Sonia M. Oliani , Amilcar S. Damazo and Mauro The effect of inflammation (carrageenin peritonitis) 3,CA Perretti was also monitored. Methods: Electron microscopy was used to define the sub-cellular localisation of ANXA1 in rat eosinophils Department of Biology, IBILCE – UNESP, Sa ˜ o Jose ´ and neutrophils extravasated in the mesenteric tis- sue. A pair of antibodies raised against the ANXA1 do Rio Preto, SP, Brazil; Department of Morphology, N-terminus (i.e. able to recognise intact ANXA1, UNIFESP – EPM, Sao ˜ Paulo, SP, Brazil; and The termed LCPS1) or the whole protein (termed LCS3) William Harvey Research Institute, Bart’s and The was used to perform the ultrastructural analysis. London, Queen Mary School of Medicine and Results: The majority of ANXA1 was localised in the Dentistry,

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Mediators of Inflammation – Unpaywall

Published: Jan 1, 2000

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