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CONTROL DEFINITION IN CASE-CONTROL STUDIES OF THE EFFICACY OF SCREENING AND DIAGNOSTIC TESTING

CONTROL DEFINITION IN CASE-CONTROL STUDIES OF THE EFFICACY OF SCREENING AND DIAGNOSTIC TESTING AMERICAN Journal of Epidemiology Fomab AMERICAN JOURNAL OF HYGIENE © 1983 by Tlie Johns Hopkins University School of Hygiene and Public Health VOL. 118 OCTOBER 1983 NO. 4 Reviews and Commentary CONTROL DEFINITION IN CASE-CONTROL STUDIES OF THE EFFICACY OF SCREENING AND DIAGNOSTIC TESTING NOEL S. WEISS1 In his article, "Case Definition in Case- impact of breast cancer (2-7) chose women Control Studies of the Efficacy of with localized breast cancer against whom Screening," Morrison (1) recommended to compare women with more extensive that the "case" group in these studies involvement. comprise individuals whose disease is The purpose of this article is to provide "sufficiently advanced to ensure diag- a more complete justification for the use nosis even without screening." The use of of controls from the "source population," such cases, without further selection in and to show how the alternative choice, terms of the method by which their dis- cases with early-stage disease, will gen- ease was detected, allows for an evalua- erally provide a biased result. tion of screening efficacy that is properly uninfluenced by the presence of a "lead- LESSONS FROM EXPERIMENTAL STUDIES time" interval. OF SCREENING EFFICACY Morrison also recommended that con- Consider a study http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Epidemiology Oxford University Press

CONTROL DEFINITION IN CASE-CONTROL STUDIES OF THE EFFICACY OF SCREENING AND DIAGNOSTIC TESTING

American Journal of Epidemiology , Volume 118 (4) – Oct 1, 1983
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Publisher
Oxford University Press
Copyright
© Published by Oxford University Press.
ISSN
0002-9262
eISSN
1476-6256
DOI
10.1093/oxfordjournals.aje.a113650
Publisher site
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Abstract

AMERICAN Journal of Epidemiology Fomab AMERICAN JOURNAL OF HYGIENE © 1983 by Tlie Johns Hopkins University School of Hygiene and Public Health VOL. 118 OCTOBER 1983 NO. 4 Reviews and Commentary CONTROL DEFINITION IN CASE-CONTROL STUDIES OF THE EFFICACY OF SCREENING AND DIAGNOSTIC TESTING NOEL S. WEISS1 In his article, "Case Definition in Case- impact of breast cancer (2-7) chose women Control Studies of the Efficacy of with localized breast cancer against whom Screening," Morrison (1) recommended to compare women with more extensive that the "case" group in these studies involvement. comprise individuals whose disease is The purpose of this article is to provide "sufficiently advanced to ensure diag- a more complete justification for the use nosis even without screening." The use of of controls from the "source population," such cases, without further selection in and to show how the alternative choice, terms of the method by which their dis- cases with early-stage disease, will gen- ease was detected, allows for an evalua- erally provide a biased result. tion of screening efficacy that is properly uninfluenced by the presence of a "lead- LESSONS FROM EXPERIMENTAL STUDIES time" interval. OF SCREENING EFFICACY Morrison also recommended that con- Consider a study

Journal

American Journal of Epidemiology – Oxford University Press

Published: Oct 1, 1983

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