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- Publisher
- Springer Journals
- Copyright
- Copyright © 2011 by Springer-Verlag
- Subject
- Engineering; Industrial Chemistry/Chemical Engineering; Biomedical Engineering; Engineering Fluid Dynamics
- ISSN
- 1613-4982
- eISSN
- 1613-4990
- DOI
- 10.1007/s10404-011-0866-6
- Publisher site
- See Article on Publisher Site
Abstract
In this article, we present an optothermal analyte preconcentration method based on temperature gradient focusing. This approach offers a flexible, noninvasive technique for focusing and transporting charged analytes in microfluidics using light energy. The method uses the optical field control provided by a digital projector as established for particle manipulation, to achieve analogous functionality for molecular analytes for the first time. The optothermal heating system is characterized and the ability to control of the heated zone location, size, and power is demonstrated. The method is applied to concentrate a sample model analyte, along a microcapillary, resulting in almost 500-fold local concentration increase in 15 min. Optically controlled upstream and downstream transport of a focused analyte band is demonstrated with a heater velocity of ∼170 μm/min.
Journal
Microfluids and Nanofluids – Springer Journals
Published: Aug 12, 2011