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- Publisher
- Springer Journals
- Copyright
- Copyright © Springer Nature America, Inc. 2011
- Subject
- Biomedicine; Biomedicine, general; Immunology; Infectious Diseases
- ISSN
- 1529-2908
- eISSN
- 1529-2916
- DOI
- 10.1038/ni.2005
- Publisher site
- See Article on Publisher Site
Abstract
The kinase mTOR has emerged as an important regulator of helper T cell differentiation. Powell and co-workers show that the mTOR complex mTORC1 selectively regulates TH1 and TH17 differentiation, whereas mTORC2 signaling is required for TH2 differentiation.
Journal
Nature Immunology – Springer Journals
Published: Apr 1, 2011