Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/springer-journals/differential-influences-of-various-arsenic-compounds-on-glutathione-ZDwEjYUX7g
References (48)
-
Maurizio Giannı̀, Marcel Koken, M. Chelbi-alix, Gérard Benoit, Michel Lanotte, Zhu Chen (1998)
Combined arsenic and retinoic acid treatment enhances differentiation and apoptosis in arsenic-resistant NB4 cells.Blood, 91 11
-
S. Chouchane, E. Snow (2001)
In vitro effect of arsenical compounds on glutathione-related enzymes.Chemical research in toxicology, 14 5
-
(1986)
Antioxidant defense systems in endothelial cells : glutathione versus catalase -
C. Hopenhayn-Rich, M. Biggs, Allan Smith (1998)
Lung and kidney cancer mortality associated with arsenic in drinking water in Córdoba, Argentina.International journal of epidemiology, 27 4
-
K. Salnikow, M. Cohen (2002)
Backing into cancer: effects of arsenic on cell differentiation.Toxicological sciences : an official journal of the Society of Toxicology, 65 2
-
R. Zakharyan, H. Aposhian (1999)
Enzymatic reduction of arsenic compounds in mammalian systems: the rate-limiting enzyme of rabbit liver arsenic biotransformation is MMA(V) reductase.Chemical research in toxicology, 12 12
-
O. Griffith (1980)
Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine.Analytical biochemistry, 106 1
-
Allan Smith, C. Hopenhayn-Rich, M. Bates, H. Goeden, I. Hertz-Picciotto, H. Duggan, R. Wood, M. Kosnett, Martyn Smith (1992)
Cancer risks from arsenic in drinking water.Environmental Health Perspectives, 97
-
W. Habig, W. Jakoby (1981)
Assays for differentiation of glutathione S-transferases.Methods in enzymology, 77
-
M. Stýblo, L. Razo, E. LeCluyse, G. Hamilton, Changqing Wang, W. Cullen, D. Thomas (1999)
Metabolism of arsenic in primary cultures of human and rat hepatocytes.Chemical research in toxicology, 12 7
-
M. Delnomdedieu, M. Basti, J. Otvos, D. Thomas (1993)
Transfer of arsenite from glutathione to dithiols: a model of interaction.Chemical research in toxicology, 6 5
-
F. David, R. Steel, J. Torrie (1961)
Principles and procedures of statistics. -
(1995)
Increased prevalence of hypertension and long - term exposure -
Jie Dai, R. Weinberg, S. Waxman, Y. Jing (1999)
Malignant cells can be sensitized to undergo growth inhibition and apoptosis by arsenic trioxide through modulation of the glutathione redox system.Blood, 93 1
-
Mingjie Zhou, Z. Diwu, Nataliya Panchuk-Voloshina, R. Haugland (1997)
A stable nonfluorescent derivative of resorufin for the fluorometric determination of trace hydrogen peroxide: applications in detecting the activity of phagocyte NADPH oxidase and other oxidases.Analytical biochemistry, 253 2
-
A. Slivka, M. Spina, G. Cohen (1987)
Reduced and oxidized glutathione in human and monkey brainNeuroscience Letters, 74
-
H. Aposhian (1997)
Enzymatic methylation of arsenic species and other new approaches to arsenic toxicity.Annual review of pharmacology and toxicology, 37
-
C. Tseng, T. Tai, C. Chong, C. Tseng, M. Lai, B. Lin, H. Chiou, Y. Hsueh, K. Hsu, Chien-Jen Chen (2000)
Long-term arsenic exposure and incidence of non-insulin-dependent diabetes mellitus: a cohort study in arseniasis-hyperendemic villages in Taiwan.Environmental Health Perspectives, 108
-
C. Nebot, M. Moutet, P. Huet, Jinzhu Xu, J. Yadan, J. Chaudière (1993)
Spectrophotometric assay of superoxide dismutase activity based on the activated autoxidation of a tetracyclic catechol.Analytical biochemistry, 214 2
-
H. Ito, K. Okamoto, K. Kato (1998)
Enhancement of expression of stress proteins by agents that lower the levels of glutathione in cells.Biochimica et biophysica acta, 1397 2
-
M. Wei, H. Wanibuchi, Shinji Yamamoto, Wei Li, Shoji Fukushima (1999)
Urinary bladder carcinogenicity of dimethylarsinic acid in male F344 rats.Carcinogenesis, 20 9
-
Thomas Kraus, G. Quidenus, K. Schaller (2000)
Normal Values for Arsenic and Selenium Concentrations in Human Lung TissueArchives of Environmental Contamination and Toxicology, 38
-
A. Meister (1991)
Glutathione deficiency produced by inhibition of its synthesis, and its reversal; applications in research and therapy.Pharmacology & therapeutics, 51 2
-
J. Keen, W. Habig, W. Jakoby (1976)
Mechanism for the several activities of the glutathione S-transferases.The Journal of biological chemistry, 251 20
-
H. Towbin, T. Staehelin, J. Gordon (1979)
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.Proceedings of the National Academy of Sciences of the United States of America, 76 9
-
(1993)
via hydrogen peroxidasedependent pathway -
Y. Liu, D. Longfellow, H. Aposhian, B. Beck, Bruce, Fowler, R. Goyer, Robert Menzerl, Toby, Rossman, C. Thompson, M. Waalkes (1999)
Arsenic: health effects, mechanisms of actions, and research issues.Environmental Health Perspectives, 107
-
M. Stýblo, L. Razo, L. Vega, D. Germolec, E. LeCluyse, G. Hamilton, W. Reed, Changqing Wang, W. Cullen, D. Thomas (2000)
Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in rat and human cellsArchives of Toxicology, 74
-
M. Stýblo, M. Stýblo, D. Thomas, David Thomas (1995)
In vitro inhibition of glutathione reductase by arsenotriglutathione.Biochemical pharmacology, 49 7
-
N. Sharma, M. Davis (1994)
Mechanism of substance P-induced hyperpolarization of porcine coronary artery endothelial cells.The American journal of physiology, 266 1 Pt 2
-
M. Bradford (1976)
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.Analytical biochemistry, 72
-
B. Rosen (1999)
Families of arsenic transporters.Trends in microbiology, 7 5
-
A. Meister (1994)
Glutathione, ascorbate, and cellular protection.Cancer research, 54 7 Suppl
-
L. Kenney, J. Kaplan (1988)
Arsenate substitutes for phosphate in the human red cell sodium pump and anion exchanger.The Journal of biological chemistry, 263 17
-
N. Ballatori (1994)
Glutathione mercaptides as transport forms of metals.Advances in pharmacology, 27
-
W. Chang, Shu Chen, Hau-Lin Wu, Guey Shi, Sei-itsu Murota, I. Morita (1991)
Cytoprotective effect of reduced glutathione in arsenical-induced endothelial cell injury.Toxicology, 69 1
-
Shan‐Kuo Han, C. Mytilineou, G. Cohen (1996)
l‐DOPA Up‐Regulates Glutathione and Protects Mesencephalic Cultures Against Oxidative StressJournal of Neurochemistry, 66
-
D. Reed (1990)
Glutathione: toxicological implications.Annual review of pharmacology and toxicology, 30
-
J. Voyta, D. Via, C. Butterfield, B. Zetter (1984)
Identification and isolation of endothelial cells based on their increased uptake of acetylated-low density lipoproteinThe Journal of Cell Biology, 99
-
H. Chiou, Wei Huang, Che-Long Su, Shu-Feng Chang, Y. Hsu, Chien-Jen Chen (1997)
Dose-response relationship between prevalence of cerebrovascular disease and ingested inorganic arsenic.Stroke, 28 9
-
M. McCabe, K. Singh, S. Reddy, B. Chelladurai, J. Pounds, J. Reiners, J. States (2000)
Sensitivity of myelomonocytic leukemia cells to arsenite-induced cell cycle disruption, apoptosis, and enhanced differentiation is dependent on the inter-relationship between arsenic concentration, duration of treatment, and cell cycle phase.The Journal of pharmacology and experimental therapeutics, 295 2
-
F. Tietze (1969)
Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues.Analytical biochemistry, 27 3
-
U. Laemmli (1970)
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature, 227
-
S. Maiti, A. Chatterjee (2001)
Effects on levels of glutathione and some related enzymes in tissues after an acute arsenic exposure in rats and their relationship to dietary protein deficiencyArchives of Toxicology, 75
-
L. Oberley, G. Buettner (1979)
Role of superoxide dismutase in cancer: a review.Cancer research, 39 4
-
A. Santra, A. Maiti, Subhankar Das, S. Lahiri, Sushil Charkaborty, D. Mazumder, D. Mazumder (2000)
Hepatic Damage Caused by Chronic Arsenic Toxicity in Experimental AnimalsJournal of Toxicology: Clinical Toxicology, 38
-
D. Paglia, W. Valentine (1967)
Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase.The Journal of laboratory and clinical medicine, 70 1
-
Y. Jing, Jie Dai, R. Chalmers-Redman, W. Tatton, S. Waxman (1999)
Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide-dependent pathway.Blood, 94 6
- Publisher
- Springer Journals
- Copyright
- Copyright © 2002 by Birkhäuser Verlag,
- Subject
- Life Sciences; Cell Biology; Biomedicine, general; Life Sciences, general; Biochemistry, general
- ISSN
- 1420-682X
- eISSN
- 1420-9071
- DOI
- 10.1007/PL00012519
- Publisher site
- See Article on Publisher Site
Abstract
The cellular response and detoxification mechanisms in porcine endothelial cells (PAECs) to arsenic trioxide (As2O3), sodium arsenite (NaAsO2) and sodium arsenate (Na2HAsO4) were investigated. NaAsO2 at 20 μM for 72 h increased Cu/Zn superoxide dismutase activity resulting in elevated intracellular hydrogen peroxide levels, but As2O3 and Na2HAsO4 did not. Trivalent arsenic compounds increased intracellular oxidized glutathione (GSSG) and total glutathione (GSH) and cellular glutathione peroxidase (cGPX) and glutathione S-transferase (GST) activity, but not glutathione reductase activity. The increased cGPX activity resulted in an elevated cellular GSSG content. Na2HAsO4 increased the cellular GSSG level at 72 h compared to controls. These results imply that the increased GSH content responding to the oxidative stress by trivalent arsenic compounds may be mainly related to the regulation of GSH turnover. The increased GST activity implies that the elevated intracellular GSH level responding to the oxidative stress may be used to conjugate arsenic in PAECs and facilitate arsenic efflux.
Journal
Cellular and Molecular Life Sciences – Springer Journals
Published: Nov 1, 2002